Navigation Links
Anti-Cancer Drug Shows Early Promise in Pulmonary Hypertension

A drug used to treat kidney cancer can prevent the development of pulmonary hypertension (high blood pressure in the lungs) in rodents, report researchers //from the University of Chicago at the 2006 annual meeting of the American Heart Association, Nov. 12-15 in Chicago. There is no curative therapy for this condition.

'We are excited about this finding because there are so few treatment options for pulmonary hypertension,' said study author Mardi Gomberg-Maitland, M.D., M.Sc., assistant professor of medicine at the University of Chicago. 'We have drugs that can slow progression of the disease but nothing that can stop or reverse the process. This is a ray of hope.'

Pulmonary hypertension and cancer share certain features. Both diseases involve abnormal cellular growth. These abnormal cells – in the case of pulmonary hypertension, those that line the blood vessels leading to the lungs – release signals that stimulate the growth of small new blood vessels to feed the renegade cells, allowing further proliferation, and thickening of the vessel walls. Sorafenib appears to interfere with that process.

Although originally designed to fight colon cancer, the drug, sorafenib (Nexavar?), proved much more effective against kidney cancer. Sorafenib inhibits an enzyme, known as Raf kinase, which plays a role in tumor-cell growth. Researchers eventually realized it also hit other targets. After clinical trials in kidney cancer patients demonstrated improved survival, it won FDA approval in December 2005.

Now, in a surprise finding, it appears to have a use in treating this cardiovascular disease.

In pulmonary hypertension, the vessels that carry blood from the heart to the lungs constrict. Their walls thicken, which narrows the opening and reduces blood flow. Pressures within the arteries build up, requiring the heart to pump harder to push blood through the narrowed tubes to the lungs. Eventually the heart can no lo
'"/>




Page: 1 2

Related medicine news :

1. Anti-Cancer Drug Restores Normal Cell Growth
2. FDA Approves Anti-Cancer Cell Drug - Zevalin
3. Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties
4. Premature Aging Can Be Managed With Anti-Cancer Drugs In Future
5. Antidepressant Drug Found To Have Anti-Cancer Effects
6. Colgate To Develop Anti-Cancer Toothpastes And Mouthwashes
7. Clinical Trials Of New Anti-Cancer Drug To Be Initiated In New Zealand
8. Small Cars, Anti-AIDS And Anti-Cancer Drugs Would Be Cheaper
9. Anti-Cancer Treatment Promises Hope in Bird Flu Treatment
10. Exercise Has An Anti-Cancer Effect
11. A New Anti-Cancer Drug Keeps Resistance Out
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Anti Cancer Drug Shows Early Promise Pulmonary Hypertension

(Date:7/9/2014)... in Russia might contribute to HIV transmission and ... researchers from Boston University Schools of Medicine and ... State University, sought to discover the effect police ... cohort of HIV-positive people with lifetime of injection ... police were more likely to share needlesincreasing HIV ...
(Date:7/9/2014)... news release is available in French . ... factors in 14 year old teens, including brain structure and ... 70% accuracy who will go on to develop binge drinking ... of conscientiousness, and other variables such as life events and ... of binge drinking. Whether or not the child had ...
(Date:7/9/2014)... extinctions around the world have been linked to ... research from the National Institute for Mathematical and ... may also contribute. , In a series ... causes severe hemorrhage of internal organs in frogs, ... frogs if they are exposed to the virus ...
(Date:7/9/2014)... Allergy and Infectious Diseases (NIAID), part of the ... clinical trial of CRS3123, an investigational oral antibiotic ... C. difficile ) infection. CRS3123 (previously known as ... difficile growth while sparing normal intestinal bacteria. , ... 30 healthy men and women ages 18 to ...
(Date:7/9/2014)... poor printing on prescription labels handed out by ... errors in taking medication, according to new research ... National Institute for the Blind)., The study, published ... found that labels on prescription medications dispensed by ... for legibility. , By simply following recommended guidelines ...
Breaking Medicine News(10 mins):Health News:BU researchers relate arrests with HIV risk environment 2Health News:What drives a child to abuse alcohol? 2Health News:Study predicts ranavirus as potential new culprit in amphibian extinctions 2Health News:NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection 2Health News:Most prescription labels fail to meet guidelines, risking dosage errors 2
... Services Outside of Houston PHOENIX, May 6 ... M. D. Anderson Cancer Center announced they will create the ... Arizona,s leading provider of health care and the nation,s leading ... unprecedented level of cancer care in Arizona.Located at US 60 ...
... May 6 The healthcare industry in ... inequalities in access to care. The public ... of the population, yet accounts for around ... http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )Public-private partnerships offer an innovative means ...
... wife Ellen honored for generous contribution to New York University College ... ... Dr. Jan Linhart, D.D.S. and his wife, Ellen Linhart, have established ... Program at Dr. Linhart’s alma mater. In honor of this act ...
... with a humanitarian award at a glittering ceremony in London last night. ... ... of the world,s largest hospital ship charity were honored with a humanitarian ... , , ,The annual Variety Club International Humanitarian Award , whose ...
... Max Muscle Sports Nutrition,s newest product innovation is L-Tox, for advanced ... along with protective and regenerative factors. , ... Anaheim, ... Administration (FDA) www.fda.gov issued a stop product use directive ...
... small non-profit Ohio Biotech firm, has confirmed that they have decoded ... currently reported Swine Flu outbreak. , ... Albany, Ohio ... of infection and the first reported American death from the new ...
Cached Medicine News:Health News:Banner Health, M. D. Anderson Announce Cancer Care Facility for Arizona 2Health News:Banner Health, M. D. Anderson Announce Cancer Care Facility for Arizona 3Health News:South Africa not Gaining the Full Benefit of PPPs in the Healthcare Sector, Says Frost & Sullivan 2Health News:South Africa not Gaining the Full Benefit of PPPs in the Healthcare Sector, Says Frost & Sullivan 3Health News:Manhattan Dentist Inducted Into The Sir Harold Acton Society 2Health News:Mercy Ships Founders Receive Humanitarian of the Year Award From Variety Club 2Health News:Mercy Ships Founders Receive Humanitarian of the Year Award From Variety Club 3Health News:Mercy Ships Founders Receive Humanitarian of the Year Award From Variety Club 4Health News:Max Muscle Sports Nutrition Offers Support for Hydroxycut Recall 2Health News:Max Muscle Sports Nutrition Offers Support for Hydroxycut Recall 3Health News:BioTech Firm Decodes Current Swine Flu BioMarkers 2Health News:BioTech Firm Decodes Current Swine Flu BioMarkers 3
(Date:1/15/2014)... WORTH, Texas , Jan. 15, 2014  Humberto C. ... Dermatology Achievement Award" from the Journal of Drugs ... Aesthetic & Clinical Conference (ODAC). The event is January 17-20, ... Florida . The ODAC ...
(Date:1/15/2014)... MultiCell Technologies, Inc. (OTC Bulletin Board: MCET.OB ... composition of matter, biological targets, mechanism of action, methods ... This patent application describes a novel class ... which interfere with the basic homeostatic cellular processes in ...
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com announces ... available in its catalogue: ... Forecast and Market Analysis to 2022 ... Atopic Dermatitis - India Drug Forecast and ...
Breaking Medicine Technology:Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 2PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 4PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 5
... YORK, Oct. 26, 2011 One week after a ... most serious of skin cancers, which causes 8,000 U.S. ... Skin Association (ASA), a collaboration of patients, families, advocates, ... scientists who have made groundbreaking discoveries and unique contributions ...
... Perrigo Company (Nasdaq: PRGO;TASE) today announced that its ... $0.08 per share, payable on December 13, 2011 ... Perrigo Company is a leading global ... and generic prescription (Rx) pharmaceuticals, infant formulas, nutritional ...
Cached Medicine Technology:American Skin Association Honors Leading Physicians and Scientists; Journalist Deborah Norville 2American Skin Association Honors Leading Physicians and Scientists; Journalist Deborah Norville 3
Full Handle Laseredge Implant Blade Knife, 5.2 mm straight. Blade dimension: 16.5 mm x 5.2 mm x 4.2 mm x 1.6 mm....
Full Handle Laseredge Crescent Blade Knife, angled bevel down. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Full Handle Laseredge Crescent Blade Knife, angled bevel up. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Full Handle Laseredge Stab Blade Knife, 22.5 blade. Blade tip dimension: 10.7 mm x 1.8 mm x 4.2 mm....
Medicine Products: