Navigation Links
Anaesthetics may Cause Brain Disorder in Elderly

Bhubaneswar: An Indian origin scientist in the US has reiterated that some general anaesthetics used in long operations may cause brain disorders// in elderly patients.

A study led by Pravat Mandal of the University of Pittsburgh Medical School, US, found that halothane and isoflurane - two anaesthetics that are inhaled - and the injected drug propofol cause symptoms of brain disorder.

These anaesthetics encourage the clumping of proteins in the brain that cause Alzheimer's, a progressive brain disorder that gradually destroys a person's memory and ability to reason and make judgments, said Mandal.

"I work on Alzheimer's, Parkinson's and dementia with Lewy body disease using the NMR scan and brain imaging. I do not know in particular what anaesthetics are used in India. However, the gaseous method is popular due to its cost," Mandal told IANS on e-mail.

"They may cause harm to elderly people," said Mandal, who is an assistant professor in the Department of Psychiatry at the university and did his Ph.D from the Indian Institute of Technology (IIT), Madras.

Anaesthetics are used to temporarily reduce or take away sensation so that surgical procedures can be performed without causing pain. They can be induced by drugs injected into a vein or through gases inhaled by the patient. These methods are often combined.

Mandal's study also found that halothane interacts directly with beta amyloid - the major constituent of amyloid plaques in the brains of people afflicted with Alzheimer's - to change its shape and increase the rate at which it binds with nearby proteins.

Just six hours of exposure to halothane was enough to trigger protein clumping similar to that seen in people with Alzheimer's, says the study that involved animals and laboratory tests.

"If the same thing occurs in humans, anaesthetics could lead to more amyloid plaques which may lead to earlier memory prob lems."

For long-term anaesthesia, physicians must pay attention to biophysical (non-clinical) research, he said.

While Parkinson's disease is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills and speech, dementia is progressive deterioration in intellectual function and other cognitive skills, leading to a decline in the ability to perform activities of daily living.

Similarly Lewy body disease is a kind of dementia caused by damage in the brain. It is similar to Alzheimer's.

The research by Mandal's team has also appeared in the New Scientist magazine.

Source-IANS
'"/>




Related medicine news :

1. Is Diabetes the Leading Cause of Kidney Failure in India
2. Antibiotics Dangerous for Diarrhoea in Children Caused by E.Coli
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Breast Cancer Surgery Causes Psychological problems
5. Arthritis Drug May Cause Liver Damage
6. Causes of weakness in the aged
7. Gene Mutation Causes Ovarian Failure
8. Does Radiation Cause Lung Cancer?
9. Chronic Diseases said to Cause Falls in the Elderly
10. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
11. Low Testosterone Levels the Cause Of Depression In Men
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded daily by environmental and ... with these stressors is to adopt a more healthful diet, but too many people ... a certified Holistic Nutritionist and the creator of the Newport Beach Cleanse and 14-Day ...
(Date:4/29/2016)... ... 29, 2016 , ... The White House announced efforts yesterday ... information about their loan terms and accounts, and more protections for borrowers. The ... and private loans, has reached $1.3 trillion, with 43 million Americans holding student ...
(Date:4/29/2016)... ... ... Spine Team Texas, a comprehensive spine physician group specializing in the treatment of ... invited to be a featured speaker at the Texas Society of the American College ... , Dr. R. Scott McPherson, a physical medicine and rehabilitation specialist, will speak ...
(Date:4/29/2016)... ... April 29, 2016 , ... The ... (CCA), is pleased to announce the launch of the GFCP Scoop ... and more. The purpose of the GFCP Scoop site is to ...
(Date:4/29/2016)... ... 29, 2016 , ... Reltok Nasal Products proudly announces that Boston Medical Products, ... nose and throat specialty, has added the KOTLER NASAL AIRWAY™ to its diverse product ... a newly patented safety device secured by nasal surgeons onto the floor of the ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... , April 29, 2016  In the ... projected to shift from systems dependent on CRTs monitors ... types of modality CRT Medical monitors and will ... are a host of foreseeable benefits to this ... will existing modalities have to be replaced in ...
(Date:4/29/2016)... , April 29, 2016 ... H1 2016" market research report that provides an ... comparative analysis at various stages, therapeutics assessment by ... administration (RoA) and molecule type, along with latest ... also reviews key players involved in the therapeutic ...
(Date:4/29/2016)... New Jersey , April 29, 2016 /PRNewswire/ ... Software Suite for Life Sciences, Product Development Capabilities ... Global Life Science Customer Base . ... solutions provider, today announced the acquisition of Skura ... a global leader in adaptive sales enablement technology ...
Breaking Medicine Technology: