Navigation Links
Amrubicin Shows Encouraging Results for Small Cell Lung Cancer Treatment

CHICAGO, Pharmion Corporation today released interim findings from its Phase II, multi-center clinical study of Amrubicin, the company's third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer.

These findings indicate favorable interim results in terms of response rate and safety when comparing Amrubicin to the current treatment standard, topotecan, in second-line treatment of platinum-sensitive small-cell lung cancer patients with extensive disease (ED-SCLC). The early results of this study were published online on the ASCO website during the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Ill.

"Oncologists have very limited treatment options available for patients with extensive-disease small cell lung cancer, and regrettably, patients with this disease still have an exceptionally poor prognosis," said Andrew R. Allen, chief medical officer of Pharmion. "We are encouraged by these initial results which suggest Amrubicin's potential to improve the treatment landscape for small cell lung cancer."

The trial compares Amrubicin and topotecan in patients with ED-SCLC that initially responded to first-line platinum-based therapy but recurred or progressed at least 90 days after completion of first-line treatment. Study participants are randomized 2:1 to receive either Amrubicin (40 mg/m2 via 5- min.infusion daily x 3 days) or topotecan (1.5 mg/m2 via 30-min. infusion daily x 5 days), both starting on Day 1 of a 21-day cycle.

Response data from 24 evaluable patients have been analyzed, 15 treated with Amrubicin and nine with topotecan. Of the 15 Amrubicin patients, 40 percent showed an objective tumor response, including two complete responses and four partial responses. All responses are confirmed. None of the nine topotecan patients showed a response to the drug. The median duration of progression free survival at the interim
'"/>




Page: 1 2

Related medicine news :

1. Experimental treatment for Ebola Virus Shows promising results in mice
2. New Prostate Cancer Vaccine Shows Promise
3. Ebola Treatment Shows Promise
4. New Drug Shows Significant Improvement In HIV-related Heart Condition
5. Greek Study Shows Living In The Hills May Be Healthier
6. Research Shows Carbon Monoxide Prevents Inflammations
7. Latest Research Shows That Multivitamins Might Not Prevent Infections In All Elderly
8. Novartis MS Drug Shows Promising Results
9. MRI Shows Emotional Changes During Menstrual Cycle
10. Bronchiolo-alveolar Carcinoma Shows Sonographic Pattern Of Pneumonia
11. AIDS drug GS 9137 Shows Promise
Post Your Comments:
(Date:7/23/2014)... patients arriving at the emergency department, the drug ... for rapid, life-saving intubation, despite decades-old studies that ... of a systematic review of 10 recent studies ... "wonder drug" are published online in Annals ... Ketamine on Intracranial and Cerebral Perfusion Pressure and ...
(Date:7/23/2014)... 23, 2014 AidJoy is delighted to announce ... Zen on September 5, 2014 from 7:00 to ... supporters are expected to attend this semi-formal event. , "We ... the past six years," says Jess Dennis, Director of Operations ... reflect on this moment in AidJoy’s history before we launch ...
(Date:7/23/2014)... Dallas, Texas (PRWEB) July 23, 2014 ... to 2020?, provides key market data on the ... provides value, in millions of US dollars, and ... US dollars), within market categories Cardiac Valve Repairs ... company shares and distribution shares data for each ...
(Date:7/23/2014)... (July 23, 2014) Statins, a class of drugs ... patient,s risk of developing Barrett,s esophagus, according to a ... , the official journal of the American Gastroenterological Association. ... with statin use. , "Patients who received statins had ... Barrett,s esophagus compared to non-users," said study author Hashem ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 With ... the leasing and financing company LeaseQ announced that ... server based software sector, they still see robust ... , To learn more about technology equipment leasing, ... and CEO of LeaseQ was quoted as saying, ...
Breaking Medicine News(10 mins):Health News:Ketamine can be a wonder drug for ER patients and their physicians 2Health News:AidJoy’s Inaugural Gala to be Held September 5, 2014 2Health News:Cardiovascular Prosthetic Devices Market in North America to 2020 Report Available at MarketOptimizer.org 2Health News:Cardiovascular Prosthetic Devices Market in North America to 2020 Report Available at MarketOptimizer.org 3Health News:Cardiovascular Prosthetic Devices Market in North America to 2020 Report Available at MarketOptimizer.org 4Health News:Cardiovascular Prosthetic Devices Market in North America to 2020 Report Available at MarketOptimizer.org 5Health News:Statin use decreases the risk of Barrett's esophagus 2Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 2Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 3
... Osteoporosis Foundation has estimated that nearly 55 percent of ... a disease of porous and brittle bones// that causes ... among Americans has been found to contribute to lower ... conducted by Katherine Tucker, PhD, director of the Epidemiology ...
... lasting modifications in the brain metabolism and blood flow ... confusion in several cancer survivors. , ,The ... Los Angeles, revealed inferior metabolism in the important region ... chemotherapy 5-10 years ago.,A spike in blood flow to ...
... declared as Breast Cancer Awareness Month and with that ... shops//. The campaign for raising funds towards breast ... cosmetics and teddy bears, as well as major charity ... ,The Boobie-Thon that has been running annually for ...
... against polio is far from over in Bihar with the ... covered in the June-July immunisation drive this year//. ,Eight ... the drive.Two new polio cases were detected in Jehanand, while ... district has also four new cases of polio, an official ...
... cancer, such as radiotherapy, surgery and drugs as well ... vary throughout the EU, according to a study published ... 3 October 2006. Access to information is also said ... survey published in Medical OncologyStatus in Europe is a ...
... children need an hour of daily physical exercise for their ... at Glasgow University studied 545 children at 36 nurseries in ... the recommended adult level of exercise - 30 minutes, three ... ,But this activity was not enough to affect ...
Cached Medicine News:Health News:Consumption of Colas Increase Risk of Osteoporosis in Older Women 2Health News:Consumption of Colas Increase Risk of Osteoporosis in Older Women 3Health News:Chemotherapy causes mental fog 2Health News:All in the Name of ‘Breast Cancer Awareness 2
(Date:7/23/2014)... WASHINGTON , July 23, 2014  Nearly 8,000 ... for Cardinal Health,s annual Retail Business Conference (RBC), ... & Convention Center. This year,s event encourages pharmacists to ... in their communities and for their future. ... pharmacy owners to network with their peers and learn ...
(Date:7/23/2014)... July 23, 2014  The management team at ... will hold a conference call on July 31, ... quarter ended June 30, 2014.  The call details ... , 8:30 am EDTDial-in numbers: , Toll free: ... 317-0790Webcast (live & archive): , www.columbialabs.com , ...
(Date:7/23/2014)... , July 23, 2014 This September ... in Las Vegas for ... by educator, author, forward thinker and private practitioner Dr. ... experts together to candidly discuss clinical and practice management ... event is a unique opportunity to welcome fresh thinking ...
Breaking Medicine Technology:Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 2Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 3Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 4Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 5Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 6Columbia Laboratories to Discuss Second Quarter 2014 Financial Results on July 31st Conference Call 22014 DOCtalk Registration Now Open 22014 DOCtalk Registration Now Open 3
... FOUNTAIN HILLS, Ariz., Sept. 23 Sunridge International ... today that it has shipped its first order ... for several Middle Eastern countries.  AME plans to ... throughout the region, while simultaneously conducting a short ...
... 23 Reportlinker.com announces that a new market ... Bayer Schering Pharma AG: PharmaVitae Profile ... Introduction This analysis examines the historical ... prescription pharma sector. The profile encompasses global company ...
Cached Medicine Technology:Sunridge Ships First Order to the Middle East 2Reportlinker Adds Bayer Schering Pharma AG: PharmaVitae Profile 2Reportlinker Adds Bayer Schering Pharma AG: PharmaVitae Profile 3Reportlinker Adds Bayer Schering Pharma AG: PharmaVitae Profile 4Reportlinker Adds Bayer Schering Pharma AG: PharmaVitae Profile 5Reportlinker Adds Bayer Schering Pharma AG: PharmaVitae Profile 6
Coronary angiographic catheter...
The entirely open modular system is especially suitable for stereotactic microsurgical procedures....
Used to negotiate tortuous vessels....
The Emerald Guidewire is intended for percutaneous introduction of catheters....
Medicine Products: