Navigation Links
Amniocentesis Safer for Pregnant Women

Amniocentesis is the most commonly prescribed invasive test performed during pregnancies in the United States. Most women fear them while doctors// recommend them based on guidelines from the American College of Obstetricians and Gynecologists. These guidelines stem from past research studies and recommendations by the CDC that were based only on maternal age. Studies that are decades old have suggested that amniocentesis increases the rate of miscarriage by 0.5% or 1 in 200 pregnancies.
However, researchers at Mount School of Medicine in conjunction with other institutions involved in the First and Second Trimester Evaluation of Risk for Aneuploidy trial (FASTER trial) have just reported in the November issue of the journal Obstetrics & Gynecology, that pregnancy miscarriage rates after routine midtrimester amniocentesis are significantly lower than rates previously published years ago in the 1970s and 1980s. This study reports that the amniocentesis procedure- related loss risk is approximately 1 in 1,600 pregnancies.M

Lead author of the study, “Pregnancy Loss Rates After Midtrimester Amniocentis”, Dr. Keith E. Eddleman, MD, Associate Professor of Obstetrics, Gynecology and Reproductive Sciences at Mount Sinai School of Medicine has found that this new study now refutes the typically quoted 0.5% pregnancy loss rate and suggests it may be even lower than 0.1%.“Women should be counseled that this older loss rate is archaic and their decision about whether or not to have an amniocentesis should be based on contemporary information about miscarriage rates with newer screening techniques, rather than just relying on general age based risks,” said Eddleman. “This new research breakthrough will have a significant effect on how women are counseled about amniocentesis by their doctors and the information they have when deciding about screening for their unborn child.”

One of the purposes of the FASTER trial was to calculate the contemporary pro cedure-related loss rate after midtrimester amniocentesis using patients who were recruited for aneuploidy screening. A total of 35,003 unselected patients were enrolled between 10 3/7 and 13 6/7 weeks of pregnancy and followed until the end of pregnancy. Two groups were derived- those who did or did not undergo amniocentesis. The rate of fetal loss was compared between these groups and the fetal loss rate less than 6 months of gestation was 1.0% and was not statistically different from the control group.

According to researchers, the procedure related loss rate after amniocentesis was 0.06%. Women undergoing amniocentesis were only 1.1 times more likely to have a spontaneous loss. Researchers concluded that the procedure related loss rate after midtrimester amniocentesis performed on patients in a contemporary clinical trial was 0.06%. There was no significant difference in loss rates between those undergoing amniocentesis and those not undergoing amniocentesis.

Aneuploidy is a chromosomal imbalance of one or a few chromosomes above or below the normal human chromosomal number of 46, which may lead a child to have abnormalities including Down Syndrome. Amniocentesis is the standard prenatal detection procedure for aneuploidy. It has been a standard clinical practice to test women using this procedure who are 35 years or older as well as women who are genetically predisposed for certain disorders.


Related medicine news :

1. Heart Surgery Is Getting Safer for the Old
2. Estrogen Patch is Safer than Pills for Heart
3. Traffic Violations Result in Safer Drivers
4. British company developing ‘Safer Cigarettes
5. Surgery Simulators Offer Better Surgeons And Safer Surgeries
6. Mapping Of Brain Highly Beneficial For Safer Brain Tumor Surgery
7. Doppler USG-Safer Technique For Detection Of Rh Diseases In Fetus
8. Enbrelr Enters Safer Zone After Recent Research
9. Child-Proof: Brain Mapping Safer for Children than Previously Thought
10. Laser Surgery Safer Than Contact Lenses?
11. Consumers, Caregivers Taking Steps to Safer Surgery
Post Your Comments:

(Date:12/1/2015)... ... December 01, 2015 , ... Baptist ... the U.S. and is the only hospital in the region providing what is ... presentation of transcatheter pacing patients were revealed recently at a medical conference and ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... however, there are professionals who believe that with innovative technologies and under the ... the patient to get the benefit of a dual-approach to his or her ...
(Date:12/1/2015)... ... December 01, 2015 , ... December 1, ... vast improvements in scientific research and discoveries, leading us to better understand the ... relief to those affected by HIV/AIDS. Mediaplanet’s cross-platform edition of “World AIDS Day” ...
(Date:12/1/2015)... ... December 01, 2015 , ... The workstation boundaries for imaging ... Information Systems launches MED-TAB™ -- the world’s first portable DICOM-calibrated medical image display, ... to December 4, 2015. , MED-TAB is expected to change teleradiology because ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... radiographic technicians must mark the film for accurate interpretation by the radiologist. The ... Fortunately, an inventor from Sacramento, Calif., has found a way to alleviate this ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Va. , Dec. 1, 2015 As ... Drug Supply Chain Security Act (DSCSA) approaches, ... small and independent pharmacies comply with looming FDA ... InfiniTrak is entering endorsement agreements with State ... pharmacy services administration organization (PSAO) to exclusively provide ...
(Date:12/1/2015)... 2015  CytoSorbents Corporation (NASDAQ: CTSO ), ... blood purification technology to reduce deadly uncontrolled inflammation ... that Dr. Phillip Chan , President & ... the LD Micro Main Event 2015 and the ... which will be held in December. ...
(Date:12/1/2015)... A federal court has denied the state of ... filed by the Pharmaceutical Care Management Association (PCMA) challenging the ... law that forces employers and consumers to pay drugstores higher ... must now defend a law that raises health care ... Mark Merritt . --> Arkansas ...
Breaking Medicine Technology: