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American Cancer Society Launches Major New Study

ortant factor is the fact that people in other countries are often willing to be enrolled in a study, historically a serious challenge in the U.S., said Dr. Calle.

Enrollment in CPS-3 will take place at 64 of the 4,800 Relay For Life events taking place across the U.S. in 2007, and continue at select Relay events through 2011 (a pilot program enrolled participants at a handful of Relay events in 2006). Relay For Life is a fun-filled overnight event designed to celebrate survivorship and raise money for research and programs of the American Cancer Society. During the event, teams of people gather at schools, fairgrounds, or parks and take turns walking or running laps. Each team tries to keep at least one team member on the track at all times.

CPS-3 will enroll men and women between the ages of 30 and 65 who have never been diagnosed with cancer (important in studies that focus on the causes of cancer), and who are willing to make a long-term commitment to the study. Enrollees spend 20 to 30 minutes at a Relay For Life event, where after consenting to participate they complete a brief study questionnaire, get a simple waist measurement, and provide a small blood sample (similar to a doctors visit).

For the next 20 or more years, Society researchers will track CPS-3 participants through questionnaires mailed every few years, identifying and studying factors associated with cancer occurrence or prevention in the study cohort.

Researchers will use the data from CPS-3 to build on evidence from a series of American Cancer Society studies that began in the 1950s and involved hundreds of thousands of volunteer participants. The Hammond-Horn study and the first Cancer Prevention Studies (CPS-I and CPS-II) have played a major role in understanding cancer prevention and risk, and have contributed significantly to the scientific literature and to the development of public health guidelines and recommendations. Those studie
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