Navigation Links
Alzheimer's a new type of diabetes: Study

Recent research demonstrates that Alzheimer's disease represents a neuro-endocrine disorder that resembles a unique form of diabetes mellitus and progresses // with severity of neuro-degeneration.

In their study, to be published in the Journal of Alzheimer's Disease, researchers demonstrate that insulin and its receptors drop significantly in the brain during the early stages of Alzheimer's disease, and that levels decline progressively as the disease becomes more severe, leading to further evidence that Alzheimer's is a new type of diabetes.

Previous studies have shown that reduced glucose utilization and energy metabolism occur early in the course of Alzheimer's disease (AD) and correlate with impaired cognition. Glucose utilization and energy metabolism are regulated by insulin and insulin-like growth factor I (IGF-I), and correspondingly, studies have shown that cognitive impairment may be improved by glucose or insulin administration.

Researchers from the Rhode Island Hospital and Brown Medical School analyzed postmortem brain tissue of 45 patients with a diagnosis of either normal aging or different degrees of Alzheimer's neurodegeneration, termed "Braak Stages."

The study mainly characterizes the abnormalities in insulin and IGF gene expression and receptor binding in brains with different Braak stage severities of AD.

Researchers analyzed insulin and insulin receptor function in the frontal cortex, a major area affected by Alzheimer's, and discovered that with increasing severity of the disease, levels of insulin receptors and the brain's ability to respond to insulin decreased markedly.

The two parallel abnormalities related to insulin in Alzheimer's found were that insulin levels decline as the disease progresses, and, that insulin and its related protein IGF-I lose their ability to bind to corresponding cell receptors, creating a resistance to the growth factors and thus causing cells t
'"/>




Page: 1 2

Related medicine news :

1. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
2. Decrease in testosterone levels lead to Alzheimers
3. Smokers are prone to Alzheimers
4. Over-The-Counter Drugs May Prevent Alzheimers
5. Alzheimers followed by head injury
6. Vitamin E useful for Alzheimers
7. Staying mentally energitic prevents Alzheimers
8. Researchers trick Alzheimers Enzyme
9. Drug Offers Hope for Alzheimers disease
10. Alzheimers with psychosis runs in families
11. Blood test may aid foretell Alzheimers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Alzheimer new type diabetes Study

(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... Stigma Associated with Mental ... Health Concerns, ... currently being recognized on TIME.com as,one of the best Web Sites ... TIME.com cites Psych Central,s simple quizzes, "Ask the,Therapist" area, and prescription ...
... a dainty, quill-like sea creature called a lancelet provides the ... million years through a four-fold duplication of the genes of ... argued in 1970 that gene duplication was the most important ... was the basis for original estimates that the human genome ...
... natural Hyaluronic Acid ... LEXINGTON, Ky., June 18 Renowned surgeon and co-founder,of ... Joseph E. Kutz has,specialized in hand and reconstructive microsurgery ... number of patients, from youths to seniors,suffering from arthritis ...
... of Data into Valid,Accurate and Consumer-Friendly Information, ... new five-star rating system for nursing facilities announced ... (CMS), the Alliance for,Quality Nursing Home Care noted ... and timely quality information and its desire,to work ...
... Inc.,(Nasdaq: HOLX ) today announced that Glenn Muir, ... Annual Healthcare Conference being,held June 24 - 26, 2008, ... Interested parties are invited to listen to a ... 25, 2008, at 12:30 PM.,Eastern Time on the investor ...
... YORK (June 18, 2008) -- Could injecting a gene ... disabling and life-threatening condition? Physician-scientists are setting out to ... gene therapy to treat severe heart failure. , ... in the New York City area where the therapy ...
Cached Medicine News:Health News:Psych Central Selected by TIME Magazine as Top 50 Web Site in 2008 for Its Top Mental Health Content and Social Media Platform 2Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 2Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 3Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 4Health News:World Renowned Hand Surgeon Helps Patients 'Conquer' Joint Discomfort Naturally 2Health News:Alliance Expresses Support for Concept Underlying New CMS 'Five-Star' Rating System for Nursing Facilities 2Health News:Alliance Expresses Support for Concept Underlying New CMS 'Five-Star' Rating System for Nursing Facilities 3Health News:Hologic to Present at the Jefferies 2nd Annual Healthcare Conference 2Health News:First gene therapy for heart failure offered at NewYork-Presbyterian/Columbia 2
(Date:12/22/2014)... 22, 2014  CytoSorbents Corporation (OTCQB:CTSOD), a critical ... purification technology to help fight deadly inflammation in ... worldwide, today announced the appointment of Dr. ... its Senior Vice President of Clinical Development, effective ... Di Russo is an accomplished pediatric cardiothoracic ...
(Date:12/22/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/h3xm6q/us ... Self-monitoring Blood Glucose Market" report to their offering. ... This market insight focuses on the developments in the ... States . Reimbursement analysis and the effects of ... more than 73 SMBG meters have been performed, based ...
(Date:12/22/2014)... LUXEMBOURG , Dec. 22, 2014  ConvaTec, a ... Paul Moraviec has been appointed Interim Chief Executive Officer ... Mr. Moraviec succeeds Ken Berger .  "The Board ... service in leading ConvaTec over the past three years," ... Board of Directors.  "We are confident that the company ...
Breaking Medicine Technology:CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5US Self-monitoring Blood Glucose Market 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... Mich. , May 4 Stryker‘s Communications ... have signed an agreement to integrate both companies’ technologies ... this collaboration, operating rooms containing the da ... System will provide surgeons and OR staff more flexibility ...
... Two Roche employees were recognized for their significant ... TWIN Awards Dinner held April 29 , 2010.  Honored were ... M. Fieldstad , Pharm.D., global head, Safety Compliance, Pharmaceutical Development Safety and ... "These women ...
Cached Medicine Technology:Stryker Enters Strategic Marketing Agreement With Intuitive Surgical 2Stryker Enters Strategic Marketing Agreement With Intuitive Surgical 3Roche Women Honored as 2010 TWIN Awardees 2Roche Women Honored as 2010 TWIN Awardees 3Roche Women Honored as 2010 TWIN Awardees 4Roche Women Honored as 2010 TWIN Awardees 5
... Size: 5.0 x 2.5 x 80 mm. Half ... by Harvey A. Lincoff, M.D. has been modified ... design. The material is a closed cell sponge ... with rounded edges to minimize scleral intrusion. These ...
... mm. Storz offers the original Scleral ... A. Lincoff, M.D. The material is ... non-toxic and non-antigenic. Implants are soft ... intrusion. These implants are packaged sterile ...
For use under curved implants. Indications: When additional buckling is required in the meridional direction. Overall length: 15.0 mm....
For use under silicone strips E5381 610, E5381 611 and E5381 710. Indications: When higher buckle is required. Overall length: 6.1 mm....
Medicine Products: