Navigation Links
Alzheimer’s Disease Drug Could Improve Quality Of Life After Radiatio

A new study in the March 17 issue of the Journal of Clinical Oncology says that a drug that is used to treat Alzheimer’s disease is also useful in improving cognitive function, mood and quality of life in brain tumor patients after they undergo radiation therapy.//

Researchers at the Wake Forest University Baptist Medical Center found that brain tumor patients who were treated for six months with donepezil (trade name: Aricept), showed a marked improvement in mental function and well as their symptoms. “Each year more than 15,000 Americans are diagnosed with a primary brain tumors, and as many as 200,000 with metastatic brain tumors, nearly all of whom receive radiation therapy,” said Edward G. Shaw, M.D. “For survivors of brain tumor radiation, symptoms of short-term memory loss and mood changes similar to those seen in Alzheimer’s disease, as well as fatigue, frequently occur, leading to a poor quality of life.” Stephen R. Rapp, Ph.D., professor of psychiatry and behavioral medicine and senior author on the paper said that donepezil, which belongs to a class of drugs called acetylcholinesterase (AChE) inhibitors, “has demonstrated efficacy in mild to severe Alzheimer’s disease and vascular dementia. The results of this initial study encourage continued investigation of donepezil and other AChE inhibitors.” The U.S. Food and Drug Administration has also approved the drug for this use. The researchers decided to go in for trying the drug since many of the symptoms after radiation for brain tumor resembled Alzheimer’s disease. “Additional research is needed to further evaluate donepezil and other AChE inhibitors in this population.” Rapp said. The drug increases the acetylcholine level in the brain, thus compensating for the loss of this chemical after radiation. Other authors include Robin Rosdhal, R.N., O.C.N., and Mike E. Robbins, Ph.D., both from radiation oncology, and Ralph B. D’Agostino Jr., Ph.D., James Lovato, M.S. and Michelle J. Naughton, Ph.D. , all from public health sciences. Contact: Robert Conn rconn@wfubmc.edu 336-716-4977 Wake Forest University Baptist Medical Center SourceEurekalert
'"/>




Related medicine news :

1. Miracle cure for Alzheimer’s around the corner
2. Vaccine for Alzheimer’s diseas
3. High Cholesterol linked to Alzheimer’s diseas
4. Further support for use of statins in Alzheimer’s disease
5. Catching Alzheimer’s Disease Earl
6. Alzheimer’s Continues to Ris
7. Midlife Brain Activity a Predictor Of Alzheimer’s Diseas
8. New Drug Combination Found To Improve Memory in Alzheimer’s Patient
9. Blood Pressure An Early Warning Sign Of Alzheimer’s Disease
10. Delaying The Progression Of Alzheimer’s Disease
11. Hope For Patient With Alzheimer’s Diseas
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the ... – Miles by Moonlight to raise money for the American Heart Association Heart Walk. ... , Teams will work together to keep their treadmills moving for 5 hours. Treadmills ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United States, single-family ... some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average ... extremely low property-tax rates, which contributes to the relatively lower cost of living ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... content management, presents its enhanced Pepper Flow promotional review platform at the ... Pepper Flow’s increased insight-driven capabilities help marketers streamline the medical, legal, and ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
Breaking Medicine Technology: