Navigation Links
Allergic reaction to DTaP vaccine persists in children

It is a must for every child to be vaccinated against diphtheria-tetanus-pertussis. The fifth and last vaccine (DTaP) given to children causes a red splotch to develop on the area.

This reaction can last a few days and the problem is that// neither of two common drugs--ibuprofen (Advil) and acetaminophen (Tylenol)--help prevent this side effect. A Group Health Cooperative study appearing in the March issue of Paediatrics features this report.

Lisa A. Jackson, MD, MPH, a senior investigator at Group Health's Center for Health Studies and the study's lead investigator said, "Often children don't notice they have it. But it can concern parents, leading to medical visits or even needless antibiotic treatment, so we'd like to make it rarer."

372 children from 4 to 6 years old who were due for their fifth DTaP dose after getting 4 doses of this vaccine since age 2 months were observed. Four in 10 children were randomly assigned to receive ibuprofen; 4 in 10, acetaminophen; and 2 in 10, placebo.

The medication was given preventively 3 times: at 2 hours before, and 6 and 12 hours after, the vaccination. About a third of each group had local reactions at least 2 inches wide. The placebo and treatment groups did not differ significantly in their proportions of children whose reactions lasted at least 3 days or whose vaccinated limb swelled by about 1 inch or more.

As an explanation by Jackson, "Acetaminophen is an effective anti-pyretic (fever reducer). But it isn't an anti-inflammatory (inflammation reducer). We certainly thought that ibuprofen, through its anti-inflammatory effect, might make the local reactions less common or severe. We all want to decrease discomfort in children, so we were disappointed not to show a prevention effect for ibuprofen; but on the other hand we got a fairly definitive answer, and that's why we do research."

The acellular vaccine, licensed in 1997, contains only those parts of the dip htheria (whooping cough) bacteria that are critical to providing immunity. The previous version--whole cellular DTP vaccine--contained whole bacteria. The newer acellular shot results in less fever in 2- and 4-month-old babies than did the older whole-cell shot. This is significant because fever can lead to seizures--rare, but serious, adverse events associated with the DTP shot.
'"/>




Related medicine news :

1. Diet Can Influence Allergic Skin Reactions
2. New Treatment For People Allergic To Cats
3. Red Color Causes The Allergic Reaction To Strawberries
4. New Insight Gained For Allergic Reactions
5. Anthroposophical Lifestyle Reduces Risk Of Allergic Disease In Children
6. Number of Allergic Anaphylaxis Episodes Are Far More Than Those Recorded
7. Eye Drug Macugen Shows Allergic Reactions
8. Allergic to Kisses?
9. Preventive Measures Proved Ineffective in Allergic Children
10. New Cooperative Research Center for Allergic Disease
11. Allergic Symptoms on the Rise in Britain
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... ... 2016 , ... W.S. Badger Co. Inc ., the maker of certified ... as one of the best small businesses for new dads by Fatherly, the digital ... businesses providing progressive benefits to new parents on the organization’s 2016 Best Places ...
(Date:5/27/2016)... ... ... This campaign aims to provide a path to improved education and awareness ... change. , As nearly 795,000 Americans suffering from a new or recurrent stoke each ... an estimated 129,000 of these people dying from stroke, it’s become our nation’s fifth-leading ...
(Date:5/27/2016)... Texas (PRWEB) , ... May 27, 2016 , ... ... satisfying Army body fat composition regulations. This is the first time that Coolsculpting ... normally screened at least every six months to ensure they meet the prescribed body-fat ...
(Date:5/27/2016)... ... 2016 , ... Each year Standard Process Inc. ... this year’s Life University winner of a $2,500 scholarship from Standard ... Awards ceremony. , Outerbridge is approaching her last quarter at Life University in ...
(Date:5/26/2016)... ... 26, 2016 , ... There are many ways to cook a hot dog, ... that Americans prefer their dogs straight off the grill. Of the 90 percent of ... way to cook a hot dog, far outpacing other cooking methods such as steaming ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... Amarantus BioScience Holdings, Inc. (OTCQX: AMBS), ... and Orphan Diseases, today announced that President & CEO Gerald ... SeeThru Equity MicroCap Conference   Where: ... , NY When: Tuesday, May 31 st , ... Where: Grand Hyatt Hotel, 109 East 42 nd St, ...
(Date:5/26/2016)... 2016   Change Healthcare , a ... solutions and technology-enabled services designed to enable ... a strategic channel partnership with SourceMed, the ... and revenue cycle management services that empower ... clinics to optimize revenue, operational efficiency and ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May ... QGEN ; Frankfurt Prime Standard: QIA) today announced that ... with Therawis Diagnostics GmbH to develop and commercialize predictive assays ... market PITX2 as a marker to predict effectiveness of anthracycline ... "We are pleased to partner with Therawis, which ...
Breaking Medicine Technology: