Navigation Links
African HIV strains more resistant to anti HIV drugs

Genetic variations in the HIV strains in Africa make it more difficult for the anti AIDS drugs to act on them according to researchers. This however does not mean that these drugs will be powerless against the virus but these drugs find it difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body.

If the drug attaches itself to the protease, then it is easier for the drug to deactivate the virus. This is difficult in two African strains called A and C subtypes of HIV, the researchers say.

Dr. Ernesto Freire of Johns Hopkins University in Baltimore, Maryland headed the team of researchers.

The commonest strain of HIV in the U.S. and other Western countries is HIV-B. But the majority of people infected with HIV live in sub-Saharan Africa. HIV-A is the dominant strain in the northern region of sub-Saharan Africa, and HIV-C is more common in southern parts of Africa.

Protease inhibitors, the drugs used in combination therapy to fight HIV infection, were all designed to treat HIV-B. These findings find a place in a report in the May 22nd issue of the journal - Proceedings of the National Academy of Sciences. Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock and hence it will be difficult to control the burgeoning AIDS situation in Africa. But he hopes that by adapting to the changes in the protease, a drug can be developed that would be effective against various subtypes of HIV as well as varieties that have become resistant to drug therapy.
'"/>




Page: 1

Related medicine news :

1. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
2. Hypertension Drug of Choice for African Americans
3. African Conference to Combat AIDS
4. Home Based HIV counseling in African Countries
5. Aspirin, Not Used By African Americans And Diabetics To Prevent Heat Problems
6. African American smokers are more prone to developing Lung cancer
7. The AIDS Pandemic May Orphan 18 Million African Children By 2010
8. African American Children More Pone to Develop Diabetes
9. African-American Women Need To Seek Advice On depression
10. Advance Funeral For AIDS-infected South African
11. Call To Protect Traditional Knowledge Of African Medicinal Plants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are ... for this recognition are considered among the top 2 percent of lawyers practicing within ... of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Comfort Keepers® of ... Cancer Society and the Road To Recovery® program to drive cancer patients to and ... other adults to ensure the highest quality of life and ongoing independence. Getting ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, ... Board will take whatever measures required to build a ... stock which is currently listed on the OTC Markets-pink ... Company Chairman and CEO, "We are seeing an anomaly ... to understand, not only by the Company, but shareholders ...
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, Inc., ... development and manufacturing of collagen and mineral based ... today that Bill Messer has joined ... to further leverage the growing portfolio of oral ... Bill joins the Collagen Matrix executive ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
Breaking Medicine Technology: