Navigation Links
African HIV strains more resistant to anti HIV drugs

Genetic variations in the HIV strains in Africa make it more difficult for the anti AIDS drugs to act on them according to researchers. This however does not mean that these drugs will be powerless against the virus but these drugs find it difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body.

If the drug attaches itself to the protease, then it is easier for the drug to deactivate the virus. This is difficult in two African strains called A and C subtypes of HIV, the researchers say.

Dr. Ernesto Freire of Johns Hopkins University in Baltimore, Maryland headed the team of researchers.

The commonest strain of HIV in the U.S. and other Western countries is HIV-B. But the majority of people infected with HIV live in sub-Saharan Africa. HIV-A is the dominant strain in the northern region of sub-Saharan Africa, and HIV-C is more common in southern parts of Africa.

Protease inhibitors, the drugs used in combination therapy to fight HIV infection, were all designed to treat HIV-B. These findings find a place in a report in the May 22nd issue of the journal - Proceedings of the National Academy of Sciences. Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock and hence it will be difficult to control the burgeoning AIDS situation in Africa. But he hopes that by adapting to the changes in the protease, a drug can be developed that would be effective against various subtypes of HIV as well as varieties that have become resistant to drug therapy.
'"/>




Page: 1

Related medicine news :

1. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
2. Hypertension Drug of Choice for African Americans
3. African Conference to Combat AIDS
4. Home Based HIV counseling in African Countries
5. Aspirin, Not Used By African Americans And Diabetics To Prevent Heat Problems
6. African American smokers are more prone to developing Lung cancer
7. The AIDS Pandemic May Orphan 18 Million African Children By 2010
8. African American Children More Pone to Develop Diabetes
9. African-American Women Need To Seek Advice On depression
10. Advance Funeral For AIDS-infected South African
11. Call To Protect Traditional Knowledge Of African Medicinal Plants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/27/2017)... MD (PRWEB) , ... July 27, 2017 , ... ... Teams of entrepreneurs will compete to form startup companies around 117 breakthrough inventions ... Heart, Lung, and Blood Institute, and National Institute of Biomedical Imaging and Bioengineering), ...
(Date:7/27/2017)... ... July 27, 2017 , ... Cremations recently surpassed traditional burials ... Association, this trend is expected to continue with over 70% of Americans projected to ... demand for new innovations that enable families to celebrate the life of a lost ...
(Date:7/26/2017)... ... 2017 , ... An inventor from Salisbury, N.C., knows the difficulties involved with ... and dignified way to keep leeches in place during therapy," she said. "That’s why ... an effective way to keep a leech in place on the skin during therapy. ...
(Date:7/26/2017)... ... July 26, 2017 , ... Written By: ... a major advancement in drug therapy for patients living with relapsing and primary ... a novel B cell targeted therapy that has been proven to significantly reduce ...
(Date:7/26/2017)... , ... July 26, 2017 , ... ... Management Solutions as part of their continued efforts to provide innovative offerings to ... the best IT resources and build dynamic, high-performing teams to address healthcare IT’s ...
Breaking Medicine News(10 mins):
(Date:7/20/2017)... -- Prime Therapeutics LLC (Prime) released this statement from its Chief ... for Clinical and Economic Review,s (ICER) public meeting ... of abuse-deterrent formulations (ADF) of opioids. Prime was the sole ... "The ICER data ... use of abuse-deterrent formulations (ADF) in opioids in terms of ...
(Date:7/14/2017)... 14, 2017 Endo International plc (NASDAQ: ENDP ... 8, 2017.  Members of its senior management team will host a ... 8:30 a.m. ET. The dial-in number to access ... (678) 509-7598, and the passcode is 45397076. Please dial in 10 ... A replay of the call will be available ...
(Date:7/13/2017)...  New York City-based market research firm Kalorama Information notes ... of.  From new products to new costs, to the threat ... completed study, Potential Pipeline Disruptors . Among ... 1.  Age-Driven Growth - True Impact Moment Arriving   ... impact the growing population and, to a more extreme extent, ...
Breaking Medicine Technology: