Navigation Links
African HIV strains more resistant to anti HIV drugs

Genetic variations in the HIV strains in Africa make it more difficult for the anti AIDS drugs to act on them according to researchers. This however does not mean that these drugs will be powerless against the virus but these drugs find it difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body.

If the drug attaches itself to the protease, then it is easier for the drug to deactivate the virus. This is difficult in two African strains called A and C subtypes of HIV, the researchers say.

Dr. Ernesto Freire of Johns Hopkins University in Baltimore, Maryland headed the team of researchers.

The commonest strain of HIV in the U.S. and other Western countries is HIV-B. But the majority of people infected with HIV live in sub-Saharan Africa. HIV-A is the dominant strain in the northern region of sub-Saharan Africa, and HIV-C is more common in southern parts of Africa.

Protease inhibitors, the drugs used in combination therapy to fight HIV infection, were all designed to treat HIV-B. These findings find a place in a report in the May 22nd issue of the journal - Proceedings of the National Academy of Sciences. Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock and hence it will be difficult to control the burgeoning AIDS situation in Africa. But he hopes that by adapting to the changes in the protease, a drug can be developed that would be effective against various subtypes of HIV as well as varieties that have become resistant to drug therapy.

Page: 1

Related medicine news :

1. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
2. Hypertension Drug of Choice for African Americans
3. African Conference to Combat AIDS
4. Home Based HIV counseling in African Countries
5. Aspirin, Not Used By African Americans And Diabetics To Prevent Heat Problems
6. African American smokers are more prone to developing Lung cancer
7. The AIDS Pandemic May Orphan 18 Million African Children By 2010
8. African American Children More Pone to Develop Diabetes
9. African-American Women Need To Seek Advice On depression
10. Advance Funeral For AIDS-infected South African
11. Call To Protect Traditional Knowledge Of African Medicinal Plants
Post Your Comments:

(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. ... his M.D from the David Geffen School of Medicine at UCLA. He trained in ... to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... Francisco, CA (PRWEB) , ... June 24, 2016 ... ... CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive ... self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the ... (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, ... Global Forecast to 2021" report to their offering. ... pharmaceutical excipients market is projected to reach USD 8.1 ... the forecast period 2016 to 2021. ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, 2016 ... Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, the ... announced today online at by the ... diabetes stand in the way of academic and community ... Foundation,s scholarship program since 2012, and continues to advocate ...
Breaking Medicine Technology: