Navigation Links
African HIV strains more resistant to anti HIV drugs

Genetic variations in the HIV strains in Africa make it more difficult for the anti AIDS drugs to act on them according to researchers. This however does not mean that these drugs will be powerless against the virus but these drugs find it difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body.

If the drug attaches itself to the protease, then it is easier for the drug to deactivate the virus. This is difficult in two African strains called A and C subtypes of HIV, the researchers say.

Dr. Ernesto Freire of Johns Hopkins University in Baltimore, Maryland headed the team of researchers.

The commonest strain of HIV in the U.S. and other Western countries is HIV-B. But the majority of people infected with HIV live in sub-Saharan Africa. HIV-A is the dominant strain in the northern region of sub-Saharan Africa, and HIV-C is more common in southern parts of Africa.

Protease inhibitors, the drugs used in combination therapy to fight HIV infection, were all designed to treat HIV-B. These findings find a place in a report in the May 22nd issue of the journal - Proceedings of the National Academy of Sciences. Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock and hence it will be difficult to control the burgeoning AIDS situation in Africa. But he hopes that by adapting to the changes in the protease, a drug can be developed that would be effective against various subtypes of HIV as well as varieties that have become resistant to drug therapy.
'"/>




Page: 1

Related medicine news :

1. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
2. Hypertension Drug of Choice for African Americans
3. African Conference to Combat AIDS
4. Home Based HIV counseling in African Countries
5. Aspirin, Not Used By African Americans And Diabetics To Prevent Heat Problems
6. African American smokers are more prone to developing Lung cancer
7. The AIDS Pandemic May Orphan 18 Million African Children By 2010
8. African American Children More Pone to Develop Diabetes
9. African-American Women Need To Seek Advice On depression
10. Advance Funeral For AIDS-infected South African
11. Call To Protect Traditional Knowledge Of African Medicinal Plants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... ... May 24, 2016 , ... Physical therapy ... focuses on repairing the musculoskeletal and neuromuscular systems of the human body without ... NYDNRehab began providing treatments for physical therapy in New York, including dynamic ...
(Date:5/24/2016)... , ... May 24, 2016 , ... ... choose the perfect data logger for each job, ensuring the best suited solution ... calibrations of MadgeTech data loggers at their lab in Istanbul. , Metroloji Okulu ...
(Date:5/24/2016)... , ... May 24, 2016 , ... ... freezing, today announced the official relaunch of its community and education hub for ... eggs. Eggsurance's mission is to create a safe and welcoming place for women ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... ... advancing the science and clinical practice of radiosurgery, is recognizing five medical residents ... radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). The awards will be presented at ...
(Date:5/24/2016)... ... May 24, 2016 , ... The number of health insurance ... 10% over last year, according to data in the forthcoming AIS’s Directory of ... stable, with a slight decrease in risk-based groups and a slight increase in ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... -- NxStage Medical, Inc. (Nasdaq: NXTM ), a ... today announced that Jeffrey H. Burbank , Chief ... of investor conferences. Where applicable, a webcast of the ...   ... Friday, June 10, 2016 1:30 p.m. ET ...
(Date:5/24/2016)... -- Joe Marziani has joined VMS BioMarketing as senior vice president of sales, announced ... role, Marziani will lead the company,s business development and sales team, exploring new opportunities ... Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... Los innovadores de COMBO[TM], ... introduce catéteres para la intervención de extremidades inferiores ... global especializada en el suministro de soluciones vasculares ... incluyendo productos para tratar la enfermedad arterial periférica. ... los dispositivos de primera entrada de la compañía ...
Breaking Medicine Technology: