Navigation Links
Adult and Children Have Varied Drug Metabolism

A new study led by Ronald Hines, professor of pediatrics at the Medical College of Wisconsin said that adult and children have very different drug metabolism. //

Both have different levels of chemicals (enzymes) in their body for the processing of the drug. These enzymes vary in concentration with age.

Hence this study suggests that more research is needed to understand how medicines affect the young.

This plays a vital role because certain drugs have to be tested specifically on children. Drug companies do not do these tests as they dislike the extra cost that has to be spent for these tests.

But the companies and drug manufacturers has to keep this in mind when it comes to certain issues such as drug effectiveness and safety during early life stages. The team studied about 14 different enzymes in children and adults.

They findings were very surprising because several of the enzymes varied in concentration at different ages.

One such is the protein CYP3A4, which helps to oxidize chemicals in the body. It was found that children in the age group of two years have around 20-50 % of the CYP3A4 when compared to the adults.

This has increased the growing concern about the lack of understanding of the effects of medicines on children.

A report by Lords select committee said that 90 % of medicines used in the treatment of newborn babies had not been tested on infants. Some of them are morphine and many anti-epileptic agents.

Hence in conclusion more number of studies has to be directed in the better understanding of the drug metabolism in children.


'"/>




Page: 1

Related medicine news :

1. Baby Talk Better Than Adult Speech
2. A question on study of Adult Stem Cell
3. Adult COPD or asthma could be effectively treated with Xopenex
4. Adult stem cells in treatment for Multiple sclerosis (MS)
5. The Key To Prevention Of Heart Disease In Adults
6. The Harmful Effects Of Stress in Young Adults
7. Abuse in Childhood Could Result In Heart Disease in Adulthood
8. Adult bone health is dependent on lifestyle we live
9. Adult Stem Cells From Fat Tissues For Healing
10. Obese Adults Undergo Less Medical Tests And More Vulnerable To Diseases
11. A New Technique For Prediction Of Adult Height
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... , ... June 24, 2016 , ... National recruitment firm ... life sciences executive with extensive sequencing and genomics experience, as Vice President of North ... Ms. Hill will be responsible for leading the sales team in the commercialization of ...
(Date:6/24/2016)... ... 2016 , ... Today, MTI-GlobalStem, a provider of optimized transfection ... to transfect cells, announces its launch of the PluriQ™ G9™ Gene Editing System ... is a complete system for culturing and transfecting human pluripotent stem cells for ...
(Date:6/24/2016)... ... , ... Finally, a bruise cream that really works. Originally designed to ... the post-surgical treatment plans of a variety of other procedures including, but not limited ... for bruising and causes a rapid resolution of bruising and inflammatory changes compared to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Southern Illinois University ... co-chairs for the Illinois State Dental Society (ISDS) Foundation’s Mission of Mercy (MOM). ... Convention Center in Collinsville. , They expect to treat approximately 2,000 ...
(Date:6/24/2016)... AZ (PRWEB) , ... June 24, 2016 , ... SpiritQuest ... the heart of West Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, ... from partner properties – the Lodge at Sedona as well as the Sedona Rouge, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Analysis 2016 - Forecast to 2022" report to their ... contains up to date financial data derived from varied research ... trends with potential impact on the market during the next ... which comprises of sub markets, regional and country level analysis. ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
Breaking Medicine Technology: