Navigation Links
Acne drug may cause depression

A drug extensively used to treat acne can cause depression. This has been supported by several tests conducted on animals.//

Recently, the drug- Roaccutane, which effectively cures serious cases of acne, has been associated with severe side-effects like suicidal behaviour. Though the packaging of the drug mentions these risks, the reason for the occurrence of such side-effects is not known. It has not been proven so far that the drug is responsible for depression; moreover, teenagers with severe acne may feel depressed being concerned about their appearance.

The effect of Roaccutane on mice was studied by a team of researchers from the University of Bath and the University of Texas in Austin. The findings were reported in Neuropsychopharmacology.

"You can't ask a mouse if it is depressed," Sarah Bailey, of the University of Bath, said yesterday. "So we used two tests to model behaviour.

"Both involved putting the mice under stress. In one, they were put in water and forced to swim; in the other, suspended by their tails. Under these circumstances mice will normally swim, climb or thrash around to try to escape, interspersed with periods of immobility when they appear to be resigned. A mouse that is depressed will spend longer in the immobile state than one that is healthy. "

The adolescent mice were given Roaccutane in doses equivalent to that given to human adolescents. The team found drastic increase in the periods of immobility in mice.

"The conclusion is that Roaccutane tends to increase depression-related behaviour in adolescent mice, " Dr Bailey said.

Retinoids is a class of chemicals that affect the manner in which genes are "read" by the body and also decrease the rate of generation of new brain cells. Roaccutane belongs to this class of chemicals. Its damaging effects on fetus have been revealed and safety measures are taken to see that women who are likely to become pregnan t do not use it.

According to new findings, brain-cell generation is essential in adolescents and adults too. There is an assumption that Roaccutane may affect the system involved in mood hormone, serotonin, production, thereby, reducing the levels. The study on the effect of Roaccutane reveals that only 5-10% are susceptible to the effect. However, retinoids may be concerned with Alzheimer's disease and schizophrenia.

Roche, the makers of Roaccutane, said in a statement: "While no causal link has been established between Roaccutane and either depression or suicide, we are constantly monitoring all available safety databases on Roaccutane worldwide."

Roaccutane hit the markets in the early 1980s to treat severe acne. Over 13 million people worldwide have been treated with the drug. The World Health Organisation reports that the use of Roaccutane has resulted in 720 cases of psychiatric problems with 84 suicides and suicide attempts.
GYT
'"/>




Related medicine news :

1. Kissing can cause Kaposi’s Sarcoma in AID
2. Kidney Stones - Interesting New Research implicates bacteria as its cause
3. Roller coasters – cause “Chronic Headache?
4. Starvation in pregnant women can cause heart disease to their children
5. And now they say infections can cause heart disease!!!!
6. And now they say infections can cause heart disease!!!!
7. Ticks may cause more diseases
8. Depression may cause delayed wound healing
9. Analgesic abuse - cause for chronic headache in children
10. Strong pain killers likely to cause miscarriage
11. Pressure on spine cause problems
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized ... have expanded their existing home health joint venture through an agreement, effective October ... a joint venture home health company with Asante, delivering clinically integrated care, for ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... HMP ... the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare ... City on October 11, 2017. , The annual award competition recognizes editorial and design ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand ... Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be ... Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection ...
(Date:10/12/2017)... ... 12, 2017 , ... Vohra Chief Medical Officer Dr. Shark ... skilled nursing facility medical directors and other clinicians at various events in October. ... "At many of these conferences we get to educate other physicians, facility nurses, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO ) ... , and named its founder as Diplomat,s chief information ... Tennessee , will operate under Diplomat subsidiary Envoy ... for health care partners to include IT outsourcing, consulting, ... "In an interoperable world, technology delivers comprehensive insight and ...
(Date:9/28/2017)... 28, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), ... call and webcast on Friday, November 3, 2017, beginning ... ending at approximately 8:30 a.m. (CDT) / 9:30 a.m. ... 2017 financial performance and guidance for 2018, Hill-Rom executives ... enhance operational performance, and long-range financial outlook through 2020. ...
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
Breaking Medicine Technology: