Navigation Links
Acne drug may cause depression

A drug extensively used to treat acne can cause depression. This has been supported by several tests conducted on animals.//

Recently, the drug- Roaccutane, which effectively cures serious cases of acne, has been associated with severe side-effects like suicidal behaviour. Though the packaging of the drug mentions these risks, the reason for the occurrence of such side-effects is not known. It has not been proven so far that the drug is responsible for depression; moreover, teenagers with severe acne may feel depressed being concerned about their appearance.

The effect of Roaccutane on mice was studied by a team of researchers from the University of Bath and the University of Texas in Austin. The findings were reported in Neuropsychopharmacology.

"You can't ask a mouse if it is depressed," Sarah Bailey, of the University of Bath, said yesterday. "So we used two tests to model behaviour.

"Both involved putting the mice under stress. In one, they were put in water and forced to swim; in the other, suspended by their tails. Under these circumstances mice will normally swim, climb or thrash around to try to escape, interspersed with periods of immobility when they appear to be resigned. A mouse that is depressed will spend longer in the immobile state than one that is healthy. "

The adolescent mice were given Roaccutane in doses equivalent to that given to human adolescents. The team found drastic increase in the periods of immobility in mice.

"The conclusion is that Roaccutane tends to increase depression-related behaviour in adolescent mice, " Dr Bailey said.

Retinoids is a class of chemicals that affect the manner in which genes are "read" by the body and also decrease the rate of generation of new brain cells. Roaccutane belongs to this class of chemicals. Its damaging effects on fetus have been revealed and safety measures are taken to see that women who are likely to become pregnan t do not use it.

According to new findings, brain-cell generation is essential in adolescents and adults too. There is an assumption that Roaccutane may affect the system involved in mood hormone, serotonin, production, thereby, reducing the levels. The study on the effect of Roaccutane reveals that only 5-10% are susceptible to the effect. However, retinoids may be concerned with Alzheimer's disease and schizophrenia.

Roche, the makers of Roaccutane, said in a statement: "While no causal link has been established between Roaccutane and either depression or suicide, we are constantly monitoring all available safety databases on Roaccutane worldwide."

Roaccutane hit the markets in the early 1980s to treat severe acne. Over 13 million people worldwide have been treated with the drug. The World Health Organisation reports that the use of Roaccutane has resulted in 720 cases of psychiatric problems with 84 suicides and suicide attempts.
GYT
'"/>




Related medicine news :

1. Kissing can cause Kaposi’s Sarcoma in AID
2. Kidney Stones - Interesting New Research implicates bacteria as its cause
3. Roller coasters – cause “Chronic Headache?
4. Starvation in pregnant women can cause heart disease to their children
5. And now they say infections can cause heart disease!!!!
6. And now they say infections can cause heart disease!!!!
7. Ticks may cause more diseases
8. Depression may cause delayed wound healing
9. Analgesic abuse - cause for chronic headache in children
10. Strong pain killers likely to cause miscarriage
11. Pressure on spine cause problems
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... ... patient payment industry today announced its strategic partnership with Connance, a healthcare ... , The two companies’ proven, proprietary technology combine to provide health systems, ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced ... Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality ... - Global Forecast to 2021" report to their ... global pharmaceutical excipients market is projected to reach USD ... in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
Breaking Medicine Technology: