Navigation Links
Abnormal Abeta - Protein Level in Human Brain Trigger Alzheimer's Risk

ery slow. But the initial test of the new technique, applied to six healthy volunteers, suggests the opposite.

'Abeta has the second-fastest production rate of any protein whose production rate has been measured so far,' says lead author Randall Bateman, M.D., assistant professor of neurology. 'In a time span of about six or seven hours, you make half the amyloid beta found in your central nervous system.'

Ideally, the production and clearance rates stay balanced, causing the overall amount of Abeta in the central nervous system to remain constant. In the healthy volunteers who were the first test subjects, Bateman found the production and clearance rates were the same. He is now applying the technique to individuals with Alzheimer's disease.

Researchers are developing Alzheimer's drugs that either decrease Abeta production or increase its clearance, Bateman notes, and the new test could be very important in determining which approach is most effective.

Prior to the new test, the only way to assess the effectiveness of a new Alzheimer's drug was to follow the mental performance of patients receiving the treatment over many months or years.

'This new test could let us directly monitor patients in clinical trials to see if the drug is really doing what we want it to do in terms of Abeta metabolism,' Bateman says. 'If further study confirms the validity of our test, it could be very valuable for determining which drugs go forward in clinical trials and at what doses.'

The test also may be useful in diagnosis of Alzheimer's prior to the onset of clinical symptoms, which occurs after Alzheimer's has inflicted widespread and largely irreversible damage to the brain.

'We hope to study whether we can develop ways to identify potential Alzheimer's patients on the basis of a metabolic imbalance between Abeta synthesis and clearance rates,' Bateman says.

The test combines technologies that h
'"/>




Page: 1 2 3

Related medicine news :

1. Early Detection Of Facial Abnormalities in a Fetus
2. Abnormal Brain Structure One Of The Reasons For Depression in Adolescents
3. Antidepressants Could Lead To Abnormal Bleeding
4. Abnormal heart rate and depression may increase death risk
5. Opioids And Abnormal Pain Perception
6. Cancer Causing Proteins Trigger Abnormal Biochemical Reactions In Cells
7. Neglect In Childhood Could Cause Abnormal Behaviour In Adults
8. Detecting Brain Abnormalities in Babies Using New Brain Scanners.
9. New Abnormal Karyotypes Discovered in China
10. Brain Abnormalities Raise the Risk of PTSD
11. Medication Abuse In Chronic Migraine May Cause Hormonal Abnormalities
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Abnormal Abeta Protein Level Human Brain Trigger Alzheimer Risk

(Date:7/10/2014)... 2014 Up to 70% of Parkinson,s disease ... their quality of life. Some patients have disturbed ... staying asleep, while other patients may be subject ... the extreme, PD patients may exhibit REM-sleep behavior ... dream re-enactment, even before motor symptoms appear. A ...
(Date:7/10/2014)... of Huddersfield could help to improve the quality of ... such as butter, mayonnaise, yoghurt and fruit drinks ... for her work. , Katerina gained her MSc degree ... now she has embarked on research for a PhD. ... is investigating the potential of carbohydrates extracted from the ...
(Date:7/10/2014)... 2014) A research review identifying the clinical indicators ... step in the process of developing evidence-based guidelines for ... report published by Neurosurgery , official ... . The journal is published by Lippincott Williams ... Kluwer Health . , Based on analysis of ...
(Date:7/10/2014)... decades, health-conscious people around the globe have taken antioxidant ... was one of the paths to good health and ... of antioxidant supplements have repeatedly dashed the hopes of ... risk. Virtually all such trials have failed to ... in several trials antioxidant supplementation has been linked with ...
(Date:7/10/2014)... the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan ... patients a new therapeutic combination to combat resistant sarcomas. ... treatment could stabilize the growth of these tumors have ... of Cancer ., Sarcomas , Sarcomas are a ... several subtypes. It can affect from children to older ...
Breaking Medicine News(10 mins):Health News:Sleep disturbances, common in Parkinson's disease, can be early indicator of disease onset 2Health News:World interest in research work on the benefits of the Okra plant 2Health News:What's a concussion? Review identifies four evidence-based indicators 2Health News:What's a concussion? Review identifies four evidence-based indicators 3Health News:How antioxidants can accelerate cancers, and why they don't protect against them 2Health News:New therapeutic combination to slow resistant sarcomas 2
... five-year international clinical study shows that acyclovir, a commonly prescribed ... not affect HIV transmission by people with both viruses. ... Transmission Study, was released by the New England Journal ... will follow in the print edition Feb. 4. ...
... ... Second Wave of H1N1 Flu: No Waiting in Long Lines , ... San Diego, Calif. (Vocus) January 25, 2009 -- U.S. ... nation, announced today that they are offering H1N1 vaccine shots for $15 per shot for ...
... for surgery than county hospitals, research shows , MONDAY, ... received by prostate cancer patients is influenced by the ... a new U.S. study has found. , Surgery was ... while patients in private facilities were more likely to ...
... , ROCHESTER, Minn. , Jan. ... the brain is the aim of a new Mayo Clinic project ... The new method uses analytics technology developed by the Mayo and ... 95 percent accuracy rate in detecting aneurysms, compared with 70 percent ...
... , NEW YORK , ... of the 25 largest PR firms ( http://www.5wpr.net/ ) in the U.S., today ... its versatile roster of fashion and lifestyle clients. Launched in 2002, the luxury ... lifestyle products using proprietary natural frequency technology. , " Philip Stein is ...
... CHESAPEAKE, Va. , Jan. 25 U.S.-based, Maison ... Haiti -based Maison Fortune Orphanage. The strategic expansion plans ... after the recent devastating earthquakes. The Orphanage, located near the ... in a sea of unimaginable turmoil. , This planned expansion ...
Cached Medicine News:Health News:Control of herpes symptoms does not reduce HIV transmission, international study found 2Health News:U.S. HealthWorks in San Diego Region Offering $15 H1N1 Vaccinations for both Walk-Ins and On-Site 2Health News:Prostate Cancer Care Varies By Hospital Type 2Health News:Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms 2Health News:Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms 3Health News:Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms 4Health News:5W Public Relations Adds Philip Stein Watches to Its Fashion & Lifestyle Client Roster 2Health News:5W Public Relations Adds Philip Stein Watches to Its Fashion & Lifestyle Client Roster 3Health News:Haitian Orphanage Takes Quick Action to Fill Void after Devastating Earthquakes 2Health News:Haitian Orphanage Takes Quick Action to Fill Void after Devastating Earthquakes 3
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and ... be able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because of the ... steadfastly remains one of the most litigious industry ...
(Date:1/15/2014)... 2014 Tegra Medical is very pleased to announce the ... new Chief Executive Officer.  Mark was promoted from his current ... the company,s four facilities in Massachusetts , ... joined Tegra Medical in 2012 with 20+ years of broad-based ...
(Date:1/15/2014)... Therapeutics, Inc. (Nasdaq: ECTE ) ("Echo"), a ... a non-invasive, wireless continuous glucose monitoring system, today announced ... Interim CEO of Echo Therapeutics, will present at "TEN", ... Mr. Doman will make a corporate presentation ...
Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... 31, 2011 Leading events organiser UBM Live ... details of a new Logistics and Supply Chain Zone ... to pharmaceutical contract services and outsourcing. ICSE will take ... Germany and is part of the world,s leading platform ...
... (NASDAQ: UPI ), announced today that the ... (NICE) issued guidance on percutaneous tibial nerve stimulation (PTNS) ... NICE issued similar guidance on PTNS treatment for overactive ... in the UK and Europe to use our Urgent® ...
Cached Medicine Technology:Logistics and Supply Chain Zone Introduced at ICSE 2011 Event 2Logistics and Supply Chain Zone Introduced at ICSE 2011 Event 3United Kingdom's National Institute for Health and Clinical Excellence Issues Guidance on Percutaneous Tibial Nerve Stimulation for Faecal Incontinence 2
Provides immediate access to comprehensive coverage of more than 325 I.V. drugs, blood products, and solutions....
... a comprehensive, authoritative drug reference to ... overdose management, Canadian drug names, OTC ... drug references and tools is included ... (ED, PRIMARY CARE PLUS, CRC, RN, ...
... patients and health consumers from the trusted ... in MedMaster includes why the medication is ... side effects and warning signs of adverse ... information on what to do if a ...
Provides reliable information on the most commonly prescribed drugs, their side effects, interactions and cost of therapy....
Medicine Products: