Navigation Links
A three-dimensional Culture System ensures Female Fertility

In women who are at risk for infertility and needing cancer therapy, it was difficult to attain follicular maturation in vitro when immature follicles were removed from their normal environment//.

But a group of researchers at the Northwestern University have created a new technology (i.e.) a three-dimensional culture system that encloses follicles, allowed normal follicular maturation in vitro and helped maintain a normal connection between follicle and egg leading to birth of a live mice.

The results are published online this month by the journal Tissue Engineering.

The study shows that follicles grown individually in a three-dimensional biomaterial called alginate maintain normal connections between follicle and egg, resulting in the development of eggs, which can be fertilized and ultimately lead to healthy embryos and the birth of live mice. Previously developed methods of growing follicles or eggs outside of the body do not provide the three-dimensional support to maintain the follicle structure in which the egg must grow.

‘While the research is in its early stages, this work has implications for the preservation of fertility for women and girls with cancer,’ said Teresa K. Woodruff, Professor of Neurobiology and Physiology who led the study together with Lonnie D. Shea, Associate Professor of Chemical and Biological Engineering. ‘This system establishes a core technology for human egg banks for preservation of fertility.’

The technology mimics the ovary and its environment. Follicles (each follicle has one egg) from mice were grown in vitro until fully matured by providing the follicles and eggs with the necessary hormones for development while maintaining their normal architecture. The eggs were then used for in vitro fertilization. The fertilized eggs were implanted into a foster mother that was of a different strain than the donor egg and sperm, resulting in babies with a different coat color, proving that the births were the result of the cultured embyros. Both male and female offspring were fertile.

Source: Eurekalet
'"/>




Related medicine news :

1. Low Cost Tissue Culture Vaccine For Encephalitis
2. Resident Physicians Need More Preparations To Treat Patients From Different Cultures
3. DNA Underwent Changes Due To Culture
4. Functional Taste Cells Cultured In Vitro
5. Study IDs Protein That Inhibits HIV From Growing In Cell Cultures
6. Scientists Re-grow Dental Enamel from Cultured Cells
7. Early Warning System For Breast Cancer
8. Gene connected to Multi-System disorder discovered
9. Reviving the Immune System
10. Painkilling Patch As Effective As Intravenous Delivery Systems
11. Wrestling found To Be Good for the Immune System
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016  American Respiratory ... testing company, is now able to perform sophisticated lung assessments in ... Medical Technologies , Inc. Patients are no longer ... to ndd,s EasyOne PRO ® , ARL patients like Jeanne R. ... testing done in the comfort of her own home. ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
Breaking Medicine Technology: