Navigation Links
A novel vaccine proves a shot in the arm for colorectal cancer patients

7 with a powder to help absorb the vaccine, 105AD7 along with BCG (a bacteria used to stimulate the immune system in cancer patients) during the first immunization and the powder in subsequent vaccinations, or no treatment.

The patients, who had varying degrees of disease, averaged age 66. Twenty-eight patients had colon cancer while in 39 patients the primary tumor was located in the rectum.

Patients were immunized before surgery on the day they were recruited for the study, and again two weeks later if surgery had not yet been performed. The vaccines were continued three, six and 12 weeks after surgery, and then at three monthly intervals up to a maximum of 24 months after surgery. Blood samples were collected from the patients during recruitment, at surgery, and at the time of the three-, six- and 12-week post-operative immunizations. Additional blood samples were acquired one month after each subsequent immunization.

Laboratory tests of the blood samples indicated that a T-cell response against the vaccine was recorded in the majority of patients. The responses tended to have two peaks: one following the start of the immunization schedule and another several months later, after additional immunizations. About 70 percent of patients produced both TNF-alpha and GM-CSF – a protein that stimulates white blood cell production – in response to both the vaccine and to CD55.

"The immune responses to both the vaccine and CD55 were measurable, adding support to the use of CD55 as a target in cancer treatment," Durrant said.

Nineteen of the patients died during the follow-up period. Durrant and colleagues noted that the trial was not designed to study the effect of the vaccines on survival.



Source-Eurekalert
SV
'"/>




Page: 1 2

Related medicine news :

1. A novel augmentation
2. Gene enchances radiation therapy - A novel approach to fight cancer
3. Cessation of blood supply to cancer cells may curtail spread, novel research
4. Lice now dried to death by novel dryer
5. New hope for cancer victims – will vaccine cure the deadly bug
6. New vaccine helps allergy and asthma patients
7. Man against HIV – new vaccine ready for human trials
8. New vaccine helps allergy and asthma patients
9. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
10. HIV did not arise from polio vaccine
11. Double impact vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: novel vaccine proves shot the arm for colorectal cancer patients

(Date:10/19/2014)... Having been working in the garment industry ... customer needs. According to James, one of the company’s top ... or with high-low skirts that add beauty to them. Chiffon ... LunaDress has unveiled its new selection of 2014 long prom ... brand new items are available in over 20 popular designs. ...
(Date:10/19/2014)... Recently, Fancyflyingfox.com, an innovative company that provides many kinds ... designs of 2014 mother of the bride dresses ... offered with big discounts, up to 70% off. All ... enjoy this special offer. , Owing to the ... one of the leading brands in the global market. ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 Visual ... program has just been released to the public ... online body building and fitness community. The commotion ... of DietsAndFitnessGuides.com's Vin Delmonico prompting an investigative review. ... of hitting what is commonly known as a ...
(Date:10/19/2014)... News) -- New stem cell-based research could improve understanding ... a new study suggests. Scientists used stem cells ... a lab dish. They then transplanted the organoids into ... according to the researchers. "This provides a new ... can cause intestinal failure, from genetic disorders appearing at ...
(Date:10/19/2014)... CHICAGO, OCTOBER 20, 2014 – The U.S. Government ... effectively treat Alzheimer,s disease by 2025. However, a ... says the research milestones in the U.S. Government,s ... broadened in scope, increased in scale, and adequately ... A series of proposals by the workgroup to ...
Breaking Medicine News(10 mins):Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2Health News:Scientists Grow, Implant Human Intestinal Tissue in Mice 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6
... on the Indian front has run into rough weather ... Parke-Davis (India). A local court in Hyderabad has ... city. ,The vacation court of the Ranga Reddy ... machinery of Parke-Davis (India) following a petition filed by ...
... has found a new treatment - Vedic vibration technology. ... Vedic Vibration Technology in subjects with arthritis,' revealed that scientists ... in 36 per cent of the patients treated and at ... cent cases. ,The study was recently conducted in Berlin ...
... certain cancers, hepatitis and multiple sclerosis with interferon therapy ... can seriously spoil its quality. Alpha interferon a ... depression. ,A new research now shows that the ... avoid this problem. Almost 50% of people on ...
... Bank, whose website (www.worldbank.org) declares "Our dream is a ... private hospital in Mumbai, India, a move which some ... assistance for projects that will mainly benefit the rich. ... state an International Development Association loan of $134m (89m), ...
... says that women with low risk pregnancies, who live in the ... during pregnancy to 3 - 6 times during pregnancy instead of ... ,However, these women are not more at risk than women ... baby, or have anemia during pregnancy, or spend longer in the ...
... Genetic variations in the HIV strains in Africa make it more ... to researchers. This however does not mean that these drugs will ... to latch on to the protease, which is an enzyme useful ... the drug attaches itself to the protease, then it is easier ...
Cached Medicine News:Health News:The World Bank funds private Hospital in India 2
(Date:10/17/2014)... Conn. , Oct. 17, 2014  UBM Medica ... online community for endocrinologists and other clinicians who treat ... comprehensive coverage on effective use of insulin .  ... eventually require insulin replacement therapy – daily ... for the progressive decline in the function of pancreatic ...
(Date:10/17/2014)...  Ameritox SM , the nation,s leader in medication ... Smith , M.D., as Chief Medical Officer. In this ... resources for healthcare providers, patients and managed care plans. ... a variety of healthcare companies that have provided him ... behavioral health sides of Ameritox,s business. He most recently ...
(Date:10/17/2014)... Oct. 17, 2014   ndd Medical Technologies , ... employing precise ultrasound technology, announced that its EasyOne Pro® ... Healthcare Center , a 140,000 square foot, 44-bed hospital ... hospital serves a large number of Native ... Oklahoma and beyond. A portion of its ...
Breaking Medicine Technology:Endocrinology Network Features Special Coverage on Effective Use of Insulin 2Endocrinology Network Features Special Coverage on Effective Use of Insulin 3Ameritox Appoints New Chief Medical Officer 2EasyOne Pro Mobile Respiratory Testing from ndd Medical Technologies Chosen by Choctaw Nation 2
... are available in 14 configurations including the ... Microgenics Antibody Technology, the SureStep MDMA (Ecstasy) ... immunoassay targeted to detect MDMA that has ... but no cross-reactivity to any isomer of ...
... Tests are available in 14 configurations including ... using Microgenics Antibody Technology, the SureStep™ MDMA ... care immunoassay targeted to detect MDMA that ... MDEA but no cross-reactivity to any isomer ...
AccuSign DOA Series tests include tests for Amphetamines, Barbituates, Benzodiazepines, Cocaine, Methadone, Methamphetamines, Nicotine (Cotinine), Opiates, Phencyclidine, THC, Tricyclic Antidepressan...
... The InstaCheck® multi-drug test device ... and easily. Negative results can ... as 3 minutes; positive results ... simple, one-time urine sample application ...
Medicine Products: