Navigation Links
A new contraceptive

A unique protein that only occurs in sperm could be the key to a new contraceptive for both the sexes.The protein, named CatSper, is an ion channel protein that controls the flow of calcium into sperm tails. Calcium is crucial in enabling sperm to swim, so a drug designed to block the channel would immobilise sperm and prevent fertilisation.

The discovery is reported by Dr David Clapham, from the Howard Hughes Medical Institute, and colleagues from Harvard Medical School."This is the only protein// I've ever seen that localises to only one tissue," said Dr Clapham. "We looked carefully through at least fifty human tissues, and the only place it turned up was in the testes."

"Futhermore, the only place it turned up within the testes was in sperm. And within sperm, it is found only in the principal piece of the tail." It is also specific to mature sperm and does not appear to be expressed in sperm precursor cells, or in immature sperm.The very specific role of the protein means that a contraceptive designed to disrupt it would have far fewer side effects than a hormone-based contraceptive. Hormones are found in many different tissues.

Working with mice, the researchers discovered that the sperm of mice without the CatSper gene were unable to penetrate the outer covering of the egg, the zona pellucida. But when the researchers mixed the sperm with eggs that had the covering removed, they fertilised normally.

A contraceptive designed to prevent fertilisation would not interfere with the gene but simply inhibit the ion channel protein, so that calcium could not pass through. "If a drug could be designed to block this ion channel specifically, it could be taken by men or women.It would not have to be taken for a very long period to block fertilisation, perhaps only just before or after intercourse", said Dr Chapman.


'"/>




Page: 1

Related medicine news :

1. Another injectable contraceptive Pill approved by FDA
2. Male contraceptive in trial
3. Hormone contraceptives lead to bone problems
4. A new male contraceptive
5. Spray on contraceptive clears Phase I trial
6. Indian Health Ministry approves sale of Emergency contraceptives as over the counter drug
7. Lower doses of oral contraceptives helpful in treating acne
8. Dermaseptins: Potent vaginal contraceptives
9. Oral contraceptives safe for women with Lupus erythematosus
10. Islamic Medical Ethics opposes Irreversible contraceptive and surrogate motherhood.
11. The conception of Anya, a period-free contraceptive pill
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... ... 28, 2017 , ... AutismOne announced the Board Certified in ... Medicine and available for application on Saturday, May 27, 2017, following Thursday, Friday, ... Springs. , Ed Arranga, president of AutismOne, stated: "Many of the modalities termed ...
(Date:3/28/2017)... ... 2017 , ... Public relations pros work hard to earn placements and ... While many results are clear, much of PR is hard to quantify. Goal-setting and ... to measurement, firms should always take an all-inclusive approach that takes both traditional and ...
(Date:3/28/2017)... ... 2017 , ... With expansion and efficiency in mind, Patten Seed Company completed ... processing plant opened in Marshallville in 2006, and a bagging and shipping facility has ... transition of Patten Seed operations to the Middle Georgia location from their previous home ...
(Date:3/28/2017)... ... 2017 , ... Oily skin is a common and unwelcomed occurrence in people of all ages, ... to offer to the discussion of dealing with excess skin oil. “Oily skin is a ... remedies that can help remove the oily shine while keeping the skin fresh and clean,” ...
(Date:3/28/2017)... ... 28, 2017 , ... Nurse practitioners and physician assistants are ... in the healthcare workforce, according to a survey recently released by PracticeMatch ... candidate leads to healthcare employers of physicians and advanced practice clinicians. , Only ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... Calif. , March 27, 2017  Cryoport, Inc. ... that it intends to offer shares of common stock ... registration statement on file with the Securities and Exchange ... and other conditions, and there can be no assurance ... completed, or as to the actual size or terms ...
(Date:3/27/2017)... , March 27, 2017 ... attendees and more than 600 exhibitors from 70 ... opportunities and solutions that will advance the medical ... 2017 at the Messe Stuttgart, Stuttgart, ... medical technology platform showcasing the key trends and ...
(Date:3/27/2017)... , March 27, 2017  Sanderling Ventures, ... by Ethicon, a division of Johnson & Johnson. Torax ... for the treatment of gastro-esophageal reflux disease (GERD). ... augmentation (MSA) technology and the procedure is currently ... Torax Medical was founded by Sanderling ...
Breaking Medicine Technology: