Navigation Links
A new contraceptive

A unique protein that only occurs in sperm could be the key to a new contraceptive for both the sexes.The protein, named CatSper, is an ion channel protein that controls the flow of calcium into sperm tails. Calcium is crucial in enabling sperm to swim, so a drug designed to block the channel would immobilise sperm and prevent fertilisation.

The discovery is reported by Dr David Clapham, from the Howard Hughes Medical Institute, and colleagues from Harvard Medical School."This is the only protein// I've ever seen that localises to only one tissue," said Dr Clapham. "We looked carefully through at least fifty human tissues, and the only place it turned up was in the testes."

"Futhermore, the only place it turned up within the testes was in sperm. And within sperm, it is found only in the principal piece of the tail." It is also specific to mature sperm and does not appear to be expressed in sperm precursor cells, or in immature sperm.The very specific role of the protein means that a contraceptive designed to disrupt it would have far fewer side effects than a hormone-based contraceptive. Hormones are found in many different tissues.

Working with mice, the researchers discovered that the sperm of mice without the CatSper gene were unable to penetrate the outer covering of the egg, the zona pellucida. But when the researchers mixed the sperm with eggs that had the covering removed, they fertilised normally.

A contraceptive designed to prevent fertilisation would not interfere with the gene but simply inhibit the ion channel protein, so that calcium could not pass through. "If a drug could be designed to block this ion channel specifically, it could be taken by men or women.It would not have to be taken for a very long period to block fertilisation, perhaps only just before or after intercourse", said Dr Chapman.


'"/>




Page: 1

Related medicine news :

1. Another injectable contraceptive Pill approved by FDA
2. Male contraceptive in trial
3. Hormone contraceptives lead to bone problems
4. A new male contraceptive
5. Spray on contraceptive clears Phase I trial
6. Indian Health Ministry approves sale of Emergency contraceptives as over the counter drug
7. Lower doses of oral contraceptives helpful in treating acne
8. Dermaseptins: Potent vaginal contraceptives
9. Oral contraceptives safe for women with Lupus erythematosus
10. Islamic Medical Ethics opposes Irreversible contraceptive and surrogate motherhood.
11. The conception of Anya, a period-free contraceptive pill
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2016)... ... 25, 2016 , ... TransactRx announces the release of enhanced ... service claims by Pharmacy Benefit Managers that were submitted by Retail Clinics and ... Cross Benefit Clearinghouse receives standard professional medical claims submitted from the retail clinic’s ...
(Date:5/25/2016)... ... May 25, 2016 , ... The University of San Francisco ... Professions. She will lead a team of more than 100 full-time faculty and staff, ... role as dean in late August. , Baker comes to USF from the University ...
(Date:5/25/2016)... FLA (PRWEB) , ... May 25, 2016 , ... ... technology to help turn back the hands of time of female aging. The ... and childbirth. Women with symptoms such as leakage, laxity, itchiness and pain have ...
(Date:5/25/2016)... Pine Brook, NJ (PRWEB) , ... May 25, 2016 , ... ... at the 2016 Annual COVD Meeting for their work on visual evoked potential and ... , summarizes recent studies that used the Diopsys® NOVA™ ERG and VEP Vision ...
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... ... builder, has announced that it will join America's leading engineers at the American ... held at the Georgia World Congress Center. , Engineers, speakers and exhibitors ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 Los innovadores ... del mundo, introduce catéteres para la intervención de ... una compañía global especializada en el suministro de ... su cartera incluyendo productos para tratar la enfermedad ... PTA son los dispositivos de primera entrada de ...
(Date:5/23/2016)... India , May 23, 2016 ... report "Patient Handling Equipment Market by Product (Wheelchair, ... of Care (Bariatric Care, Critical Care, Wound), Accessories ... - Forecast to 2021", published by MarketsandMarkets, the ... USD 17.18 Billion by 2021 at a CAGR ...
(Date:5/23/2016)... Clarifying Vision - Prospects and ... Vision Care What can be expected from ... grow at the fastest rates? This visiongain ... trends, opportunities and prospects. ,Our 190-page ... most lucrative areas in the industry and the future ...
Breaking Medicine Technology: