Navigation Links
A new contraceptive

A unique protein that only occurs in sperm could be the key to a new contraceptive for both the sexes.The protein, named CatSper, is an ion channel protein that controls the flow of calcium into sperm tails. Calcium is crucial in enabling sperm to swim, so a drug designed to block the channel would immobilise sperm and prevent fertilisation.

The discovery is reported by Dr David Clapham, from the Howard Hughes Medical Institute, and colleagues from Harvard Medical School."This is the only protein// I've ever seen that localises to only one tissue," said Dr Clapham. "We looked carefully through at least fifty human tissues, and the only place it turned up was in the testes."

"Futhermore, the only place it turned up within the testes was in sperm. And within sperm, it is found only in the principal piece of the tail." It is also specific to mature sperm and does not appear to be expressed in sperm precursor cells, or in immature sperm.The very specific role of the protein means that a contraceptive designed to disrupt it would have far fewer side effects than a hormone-based contraceptive. Hormones are found in many different tissues.

Working with mice, the researchers discovered that the sperm of mice without the CatSper gene were unable to penetrate the outer covering of the egg, the zona pellucida. But when the researchers mixed the sperm with eggs that had the covering removed, they fertilised normally.

A contraceptive designed to prevent fertilisation would not interfere with the gene but simply inhibit the ion channel protein, so that calcium could not pass through. "If a drug could be designed to block this ion channel specifically, it could be taken by men or women.It would not have to be taken for a very long period to block fertilisation, perhaps only just before or after intercourse", said Dr Chapman.


'"/>




Page: 1

Related medicine news :

1. Another injectable contraceptive Pill approved by FDA
2. Male contraceptive in trial
3. Hormone contraceptives lead to bone problems
4. A new male contraceptive
5. Spray on contraceptive clears Phase I trial
6. Indian Health Ministry approves sale of Emergency contraceptives as over the counter drug
7. Lower doses of oral contraceptives helpful in treating acne
8. Dermaseptins: Potent vaginal contraceptives
9. Oral contraceptives safe for women with Lupus erythematosus
10. Islamic Medical Ethics opposes Irreversible contraceptive and surrogate motherhood.
11. The conception of Anya, a period-free contraceptive pill
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try ... Clay” the health benefits of integrating clay into a daily diet are numerous, as ... motivational speaker, Perry A~ has since dedicated her life to learning about the benefits ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... wide variety of organizations. DocuSyst provides a cloud hosted environment for FileHold ... installations include integration with various 3rd party applications using the FileHold web services ...
(Date:2/8/2016)... ... February 08, 2016 , ... GrassrootsHealth published data from its ... 2 diabetes in the GrassrootsHealth cohort with substantially higher vitamin D levels than ... public health,” states Carole Baggerly, Director of GrassrootsHealth, “the safety and benefits ...
(Date:2/8/2016)... KS (PRWEB) , ... February 08, 2016 , ... TopConsumerReviews.com ... leader in Mole removal products. , Moles are derived from a cluster of melanin ... in all the wrong places and create a lifetime of embarrassment. Historically, mole ...
(Date:2/8/2016)... ... 2016 , ... Guruji Mahendra Kumar Trivedi is offering 3 days of accelerated ... his birthday on February 10th. During this time, people can achieve better health, ... 250,000 people from over 40 different countries as an “ordinary man with an extraordinary ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 Nueterra, ... formerly specialized in the development of equity ... that it has divided its interests between ... Nueterra Capital will continue the founding company,s ... will operate a national system of integrated ...
(Date:2/8/2016)... , Feb. 8, 2016   HighPoint Solutions ... Group (NRG),s pharmacovigilance technology services division.  NRG ... services and an Oracle Argus Specialized partner, providing ... Life Sciences companies. --> ... HighPoint,s life sciences capabilities and provides a global ...
(Date:2/8/2016)... --  Intarcia Therapeutics, Inc. today announced the appointment ... newly created role of Vice President, Head of Global ... decades of leadership experience at leading pharmaceutical, biotechnology, and ... center. Most recently Dr. Yee served as VP, Head ... Medical Officer at AstraZeneca, where he led medical affairs ...
Breaking Medicine Technology: