Navigation Links
A glowing energy measure for heart cells

A team of scientists from Bristol University has developed a technique, using luciferase, to measure energy levels in living heart cells that will aid in detecting// damage to heart cells after a heart attack.

The scientists expect this technique to pave way for rapid recovery from cardiac arrests and heart surgery. This study was published in the Friday’s issue of the Journal of Biological Chemistry.

Dr Elinor Griffiths and her team carried out a detailed investigation on cell mitochondria - the powerhouse of cells. Energy from food is converted into ATP chemical energy by mitochondria.
In order to study the working of a heart cell mitochondria, the researchers used the protein; luciferase, usually present in the tails of fireflies. Luciferase glows in the presence of ATP. Thus, the intensity of light serves as a meter to measure the amount of ATPs generated by the mitochondria.

"Exactly how mitochondria tailor the supply of ATP to demand is not fully known. But being able to directly measure cellular ATP levels should aid understanding," said Dr. Griffiths.

Generally, heart cells have the capacity to produce energy rapidly. But, the researchers have discovered an energy lag when the cells have to begin beating suddenly from a state of rest, like after a cardiac arrest. This pause could possibly alter the normal beating of heart and sequentially deteriorate the patient’s condition.

"We know already during cardiac surgery these energy levels within the heart will drop because surgeons have to stop the heart when they operate on it. Eventually, we hope to find a way to either prevent the energy levels from dropping or enable them to recover very quickly," she said.

"Drugs are already in existence to help protect mitochondria from damage and preserve their function. If we can get those into the heart at the right time then we could protect the mitochondria and get them to produce more ene rgy," she added.

Prof. Peter Weissberg, Medical Director of the British Heart Foundation, which funded the research, said, "This work is at the cutting edge of molecular imaging and allows scientists to follow, in real time, what is happening to the energy supply inside heart cells."
GY
'"/>




Related medicine news :

1. For better mood and energy!! Work-up in short span
2. Should we avoid energy drinks to protect our teeth?
3. Burning energy and its impact on health during exercise can be of genetic origin
4. Lactic acid a potent energy giver if used properly!
5. Multiple Low-energy Plasma Skin Treatments Beneficial in Reducing Facial Wrinkles
6. A better way to measure cholesterol
7. Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time
8. Effective family control measures and stem cell research focus of Indian Government
9. India should increase precautionary measures against Bird flu
10. eGFR Diagnostic Test -A reliable and understandable measure of kidney impairment
11. Severity of heart failure in elderly can be measured with a seven-point system
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
(Date:6/23/2016)... PRINCETON, N.J. , June 23, 2016  Guerbet ... of Premier Inc.,s Supplier Horizon Award . ... this year, Guerbet was recognized for its support of ... value creation through clinical excellence, and commitment to lower ... delighted to receive this recognition of our outstanding customer ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
Breaking Medicine Technology: