Navigation Links
A glowing energy measure for heart cells

A team of scientists from Bristol University has developed a technique, using luciferase, to measure energy levels in living heart cells that will aid in detecting// damage to heart cells after a heart attack.

The scientists expect this technique to pave way for rapid recovery from cardiac arrests and heart surgery. This study was published in the Friday’s issue of the Journal of Biological Chemistry.

Dr Elinor Griffiths and her team carried out a detailed investigation on cell mitochondria - the powerhouse of cells. Energy from food is converted into ATP chemical energy by mitochondria.
In order to study the working of a heart cell mitochondria, the researchers used the protein; luciferase, usually present in the tails of fireflies. Luciferase glows in the presence of ATP. Thus, the intensity of light serves as a meter to measure the amount of ATPs generated by the mitochondria.

"Exactly how mitochondria tailor the supply of ATP to demand is not fully known. But being able to directly measure cellular ATP levels should aid understanding," said Dr. Griffiths.

Generally, heart cells have the capacity to produce energy rapidly. But, the researchers have discovered an energy lag when the cells have to begin beating suddenly from a state of rest, like after a cardiac arrest. This pause could possibly alter the normal beating of heart and sequentially deteriorate the patient’s condition.

"We know already during cardiac surgery these energy levels within the heart will drop because surgeons have to stop the heart when they operate on it. Eventually, we hope to find a way to either prevent the energy levels from dropping or enable them to recover very quickly," she said.

"Drugs are already in existence to help protect mitochondria from damage and preserve their function. If we can get those into the heart at the right time then we could protect the mitochondria and get them to produce more ene rgy," she added.

Prof. Peter Weissberg, Medical Director of the British Heart Foundation, which funded the research, said, "This work is at the cutting edge of molecular imaging and allows scientists to follow, in real time, what is happening to the energy supply inside heart cells."
GY
'"/>




Related medicine news :

1. For better mood and energy!! Work-up in short span
2. Should we avoid energy drinks to protect our teeth?
3. Burning energy and its impact on health during exercise can be of genetic origin
4. Lactic acid a potent energy giver if used properly!
5. Multiple Low-energy Plasma Skin Treatments Beneficial in Reducing Facial Wrinkles
6. A better way to measure cholesterol
7. Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time
8. Effective family control measures and stem cell research focus of Indian Government
9. India should increase precautionary measures against Bird flu
10. eGFR Diagnostic Test -A reliable and understandable measure of kidney impairment
11. Severity of heart failure in elderly can be measured with a seven-point system
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... ... Kasmer, a legally blind and certified personal trainer is helping to develop a weight loss ... plans to fix the two major problems leading the fitness industry today:, ... , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) reported today ... to build a strong and stable market for trading ... the OTC Markets-pink current trading platform. Explains ... seeing an anomaly in market trading activities that may ... Company, but shareholders and market players as well. I ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... Va. , June 24, 2016 The ... set of recommendations that would allow biopharmaceutical ... (HCEI) with entities that make formulary and coverage decisions, ... the "value" of new medicines. The recommendations ... does not appear on the drug label, a prohibition ...
Breaking Medicine Technology: