Navigation Links
A glowing energy measure for heart cells

A team of scientists from Bristol University has developed a technique, using luciferase, to measure energy levels in living heart cells that will aid in detecting// damage to heart cells after a heart attack.

The scientists expect this technique to pave way for rapid recovery from cardiac arrests and heart surgery. This study was published in the Friday’s issue of the Journal of Biological Chemistry.

Dr Elinor Griffiths and her team carried out a detailed investigation on cell mitochondria - the powerhouse of cells. Energy from food is converted into ATP chemical energy by mitochondria.
In order to study the working of a heart cell mitochondria, the researchers used the protein; luciferase, usually present in the tails of fireflies. Luciferase glows in the presence of ATP. Thus, the intensity of light serves as a meter to measure the amount of ATPs generated by the mitochondria.

"Exactly how mitochondria tailor the supply of ATP to demand is not fully known. But being able to directly measure cellular ATP levels should aid understanding," said Dr. Griffiths.

Generally, heart cells have the capacity to produce energy rapidly. But, the researchers have discovered an energy lag when the cells have to begin beating suddenly from a state of rest, like after a cardiac arrest. This pause could possibly alter the normal beating of heart and sequentially deteriorate the patient’s condition.

"We know already during cardiac surgery these energy levels within the heart will drop because surgeons have to stop the heart when they operate on it. Eventually, we hope to find a way to either prevent the energy levels from dropping or enable them to recover very quickly," she said.

"Drugs are already in existence to help protect mitochondria from damage and preserve their function. If we can get those into the heart at the right time then we could protect the mitochondria and get them to produce more ene rgy," she added.

Prof. Peter Weissberg, Medical Director of the British Heart Foundation, which funded the research, said, "This work is at the cutting edge of molecular imaging and allows scientists to follow, in real time, what is happening to the energy supply inside heart cells."
GY
'"/>




Related medicine news :

1. For better mood and energy!! Work-up in short span
2. Should we avoid energy drinks to protect our teeth?
3. Burning energy and its impact on health during exercise can be of genetic origin
4. Lactic acid a potent energy giver if used properly!
5. Multiple Low-energy Plasma Skin Treatments Beneficial in Reducing Facial Wrinkles
6. A better way to measure cholesterol
7. Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time
8. Effective family control measures and stem cell research focus of Indian Government
9. India should increase precautionary measures against Bird flu
10. eGFR Diagnostic Test -A reliable and understandable measure of kidney impairment
11. Severity of heart failure in elderly can be measured with a seven-point system
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... MD (PRWEB) , ... October 12, 2017 , ... The ... of Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual ... – 8. , In honor of Morris F. Collen, a pioneer in the field ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., ... analytics, today announced that it has been ranked #1 by ... Black Book™ Rankings 2017 User Survey. ZirMed was recognized ... for large hospitals and medical centers over 200 beds and ... Book,s healthcare technology user survey history. ...
(Date:9/13/2017)... ATLANTA , Sept. 13, 2017   OrthoAtlanta ... to the Atlanta Football Host Committee (AFHC) for the 2018 ... Monday, Jan. 8, 2018, at Mercedes-Benz Stadium in ... part of the AFHC "I,m In" campaign, participating in many ... ...
(Date:9/12/2017)... FRANCISCO , Sept. 12, 2017  ValGenesis ... Management Solutions (VLMS), is pleased to announce the ... a member of its Board of Directors and ... ValGenesis VLMS enables life science companies to manage ... the use of paper in this process. Furthermore, ...
Breaking Medicine Technology: