Navigation Links
A gene(Y) linked to blindness (AMD)!

It has bugged researchers for long to detect the cause of blindness-inducing neurodegenerative diseases such as age-related macular// degeneration (AMD) and retinitis pigmentosa (RP).

The only thing known was that they are genetic, but the problem was that AMD and RP belong to a complex family of disorders and further there are many forms of that disorder encoded by a distinct genetic form.

University of Wisconsin-Madison researchers worked with fruit flies and discovered a common gene, calnexin that causes the degenerative disease.

Calnexin-found in both fruit flies and humans-functions as a cellular chaperone. It makes sure that proteins "fold” properlyand reach the destination cell. Modulating calcium levels, which is critical for proper vision, is also its function.

"Understanding the basic mechanisms of how proteins are folded holds the key to finding treatments for not only retinal degenerative diseases but also other neurodegenerative diseases such as Alzheimer's, Huntington's and Parkinson's.", was the researchers statement to say that future work would now become easier.

To detect the calnexin mutation, the UW-Madison team used genetic mapping to zero in on the exact region harbouring the mutant. "The more mutations we identify the easier it will be to step back and look at the big picture of the general principles of neurodegeneration.” was what the researcher had to say.
'"/>




Page: 1

Related medicine news :

1. El Ni?o cycles linked to cholera outbreaks
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Gene linked to early puberty in girls
4. Maternal alcohol consumption linked to behavioral problems in children
5. Gene HPA-2 Met linked to cardiac arrest
6. Early puberty linked to nutrition
7. Alcohol linked to brain activity
8. Cement injections linked to osteoporosis
9. Asthma linked to obesity
10. Miscarriage linked to late embryos
11. Cirrhosis linked to genes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is ... vendors and unique items from across the nation, this holiday-themed event will raise funds ... by the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... CA (PRWEB) , ... October 12, 2017 , ... ... Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent technology. ... a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances can ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
(Date:9/22/2017)... AVACEN Medical (AVACEN) announced that its CE-Marked ... those with the widespread pain associated with fibromyalgia in ... Essex, England commented, "I had ... no sleep at all, tremendous pain, with every movement ... [the AVACEN 100] enough, how this has and is ...
(Date:9/19/2017)... Ky. , Sept. 19, 2017   ZirMed Inc ... predictive analytics, today announced that it has been ranked #1 ... Black Book™ Rankings 2017 User Survey. ZirMed was ... solution for large hospitals and medical centers over 200 beds ... Black Book,s healthcare technology user survey history. ...
Breaking Medicine Technology: