Navigation Links
A gene(Y) linked to blindness (AMD)!

It has bugged researchers for long to detect the cause of blindness-inducing neurodegenerative diseases such as age-related macular// degeneration (AMD) and retinitis pigmentosa (RP).

The only thing known was that they are genetic, but the problem was that AMD and RP belong to a complex family of disorders and further there are many forms of that disorder encoded by a distinct genetic form.

University of Wisconsin-Madison researchers worked with fruit flies and discovered a common gene, calnexin that causes the degenerative disease.

Calnexin-found in both fruit flies and humans-functions as a cellular chaperone. It makes sure that proteins "fold” properlyand reach the destination cell. Modulating calcium levels, which is critical for proper vision, is also its function.

"Understanding the basic mechanisms of how proteins are folded holds the key to finding treatments for not only retinal degenerative diseases but also other neurodegenerative diseases such as Alzheimer's, Huntington's and Parkinson's.", was the researchers statement to say that future work would now become easier.

To detect the calnexin mutation, the UW-Madison team used genetic mapping to zero in on the exact region harbouring the mutant. "The more mutations we identify the easier it will be to step back and look at the big picture of the general principles of neurodegeneration.” was what the researcher had to say.
'"/>




Page: 1

Related medicine news :

1. El Ni?o cycles linked to cholera outbreaks
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Gene linked to early puberty in girls
4. Maternal alcohol consumption linked to behavioral problems in children
5. Gene HPA-2 Met linked to cardiac arrest
6. Early puberty linked to nutrition
7. Alcohol linked to brain activity
8. Cement injections linked to osteoporosis
9. Asthma linked to obesity
10. Miscarriage linked to late embryos
11. Cirrhosis linked to genes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... Wethersfield, Conn. (PRWEB) , ... March 28, 2017 ... ... company based in Wethersfield, Conn., has relocated its corporate headquarters to a new, ... and clients. , In October 2016, Qualidigm purchased a distressed office building ...
(Date:3/28/2017)... Petersburg Florida (PRWEB) , ... March 28, 2017 , ... ... Marine Corp to raise money to for the Toys for Tots Literacy Campaign at ... federal budget in excess of $70 billion, the U.S. ranks at number 14 internationally ...
(Date:3/28/2017)... ... March 28, 2017 , ... Public relations pros work hard to earn placements ... channels. , While many results are clear, much of PR is hard to quantify. ... it comes to measurement, firms should always take an all-inclusive approach that takes both ...
(Date:3/28/2017)... ... , ... Thank you to all who attended Capio Partners Winter 2017 Healthcare ... exclusive to providers and offered an opportunity to collaborate and network with healthcare colleagues ... Hyatt where attendees gathered for a lively discussion on trends and issues that healthcare ...
(Date:3/27/2017)... ... March 27, 2017 , ... The respected dental team at ... teeth without the extensive time commitment and aesthetic disadvantages of traditional braces can ... A custom-designed series of virtually invisible aligners are created for each patient and ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... 2017  Akcea Therapeutics, a subsidiary of Ionis Pharmaceuticals, Inc. ... of directors: Christopher Gabrieli ... serve as chairman of the board of Akcea Therapeutics. ... of Forest Laboratories. Sandford D. Smith ... "We are excited to announce this expansion to ...
(Date:3/28/2017)... SAN FRANCISCO , March 28, 2017 ... market  is expected to reach a value of USD ... by Grand View Research, Inc. Proper closure of injured ... tissue,s structure and function. Postoperative leakages occur in 3% ... serious complication. They are responsible for one third of ...
(Date:3/27/2017)... The National University of Singapore (NUS) ... company, signed a Memorandum of Understanding (MOU) recently ... the region. Under this MOU, ... Technology (BIGHEART) at NUS and Holmusk will establish ... healthcare IT and medical device development. These include ...
Breaking Medicine Technology: