Navigation Links
A gene(Y) linked to blindness (AMD)!

It has bugged researchers for long to detect the cause of blindness-inducing neurodegenerative diseases such as age-related macular// degeneration (AMD) and retinitis pigmentosa (RP).

The only thing known was that they are genetic, but the problem was that AMD and RP belong to a complex family of disorders and further there are many forms of that disorder encoded by a distinct genetic form.

University of Wisconsin-Madison researchers worked with fruit flies and discovered a common gene, calnexin that causes the degenerative disease.

Calnexin-found in both fruit flies and humans-functions as a cellular chaperone. It makes sure that proteins "fold” properlyand reach the destination cell. Modulating calcium levels, which is critical for proper vision, is also its function.

"Understanding the basic mechanisms of how proteins are folded holds the key to finding treatments for not only retinal degenerative diseases but also other neurodegenerative diseases such as Alzheimer's, Huntington's and Parkinson's.", was the researchers statement to say that future work would now become easier.

To detect the calnexin mutation, the UW-Madison team used genetic mapping to zero in on the exact region harbouring the mutant. "The more mutations we identify the easier it will be to step back and look at the big picture of the general principles of neurodegeneration.” was what the researcher had to say.
'"/>




Page: 1

Related medicine news :

1. El Ni?o cycles linked to cholera outbreaks
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Gene linked to early puberty in girls
4. Maternal alcohol consumption linked to behavioral problems in children
5. Gene HPA-2 Met linked to cardiac arrest
6. Early puberty linked to nutrition
7. Alcohol linked to brain activity
8. Cement injections linked to osteoporosis
9. Asthma linked to obesity
10. Miscarriage linked to late embryos
11. Cirrhosis linked to genes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/21/2017)... ... July 21, 2017 , ... The Karen ... services to communities in the greater Birmingham area, is joining the Chris Hammond ... young people in the region. , The Chris Hammond Youth Foundation maintains athletic ...
(Date:7/21/2017)... ... July 21, 2017 , ... Bernard R. Bach, Jr., MD, orthopaedic surgeon ... American Orthopaedic Society of Sports Medicine (AOSSM) , received the 2017 Robert E. Leach ... in Toronto, Canada. This prestigious award is given annually to honor those who have ...
(Date:7/21/2017)... LOUIS, MO (PRWEB) , ... July 21, 2017 , ... ... born knowing how to tie their shoes,” says Suzanne Tucker, Founder of St. Louis-based ... the Time-In Toolkit, which launches on Kickstarter on Monday, July 21st. , The ...
(Date:7/21/2017)... CANADA (PRWEB) , ... July 21, 2017 , ... ... insight into why concussion rates are on the rise, say researchers presenting their ... today in Toronto, Ontario, Canada. , “The combination of evaluating the patterns of ...
(Date:7/20/2017)... ... July 20, 2017 , ... Coats Rose, ... pleased to announce their expansion to the Midwest with the establishment of the ... and Ronald Bell, and of counsels, John Peck and Robert Bruns, will establish ...
Breaking Medicine News(10 mins):
(Date:7/17/2017)... Fla. , July 17, 2017  MedX Holdings, ... branded medical testing, strengthening and rehabilitation equipment, today announced ... Machine Program. MedX is considered the gold standard for ... leader in specialized medical strengthening equipment. ... a lease with the physician or practice who prescribe ...
(Date:7/14/2017)... plc (NASDAQ: ENDP ) will announce its second-quarter 2017 ... management team will host a conference call and webcast before the ... The dial-in number to access the call is U.S./ Canada ... 45397076. Please dial in 10 minutes prior to the scheduled start ... the call will be available from August 8, 2017 at 11:30 ...
(Date:7/13/2017)... Medical Products, a leader in medical product innovation and global patient ... for hospice patient care. ... Centurion Medical Products ... pain management and emotional comfort are part of a hospice,s primary ... preventing unneeded emergency department admission due to severe fecal impaction. One ...
Breaking Medicine Technology: