Navigation Links
A Synthetic Molecule Instigates Cancer Cells To Self-Harm

Scientists have devised a method to outwit cancer cells and instigate them to self-harm, ultimately causing death of cancer cells. This novel discovery could unlock reliable// treatments for cancer.

This discovery works on the known principle that involves the activation of the body’s many defenses, to check the abnormal growth of cells; the way to achieve this is to get the faulty cells to kill themselves. This natural process, termed as apoptosis, involves he role of a protein called procaspase-3. When triggered, procaspase-3 changes into an enzyme called caspase-3, that causes the cells to die.

During cancer, this mechanism in the body is rendered defective, which is why the abnormal growth of cells carries on unchecked. Often the cancers are pretty strong to combat the natural defense forces in the body, and are stronger than the chemotherapy drugs.

But Paul Hergenrother, a chemist at the University of Illinois at Urbana-Champaign, has discovered a method to get the natural biological process, to go on unimpeded, which is to have a synthetic molecule that actually triggers apoptosis. For this, the team scrutinized 20,000 different compounds that portrayed the abilities to change procaspase-3 into caspase-3. This potent molecule was termed as PAC -1

PAC-1 was found to be able to obliterate many types of cancer cells, but its efficacy was based upon the levels of procaspase-3 in the body.

Quoting the words of Prof Hergenrother, "As such, the potential effectiveness of a compound such as PAC-1 could be assessed ... with a high degree of accuracy, and people with cancer could be pre-selected for treatment with a procaspase-3 activator based on the concentration of procaspase-3 in their tumor cells."
'"/>




Page: 1

Related medicine news :

1. New Study Will The Look Into The Effects Of Synthetic Steroids
2. Synthetic protein found to relieve arthritis symptoms in animal model
3. Synthetic Bone Tissue Could Be the Answer to Disfigurement Caused by Oral Cancer
4. Synthetic DNA Makes Better Hydrogels for Drug Delivery
5. Super Chow, Laced With Semi-Synthetic Vitamin E, Inhibited Spread of Cancer
6. Synthetic Chemicals May Trigger Breast Cancer
7. Synthetic Cannabinoid Could Improve Fertility in Smokers
8. Chemicals Used To Make Synthetic Color Can Cause Cancer And Permanent Blindness
9. New Molecule that can stop the growth of Viruses
10. Puberty may be due to GPR54 gene and KiSS-1 Molecule
11. Molecule responsible for muscle repair identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/22/2017)... ... May 22, 2017 , ... Faithfully following pop culture, people today are ... toned and shaped through fitness programs. It carries on to skin nourished, pampered and ... an irresistible, radiant smile. CDA has found that just like a perfectly ...
(Date:5/21/2017)... ... May 19, 2017 , ... HealthSmart, the largest independent ... (Jim) Vertino as Chief Information Officer (CIO). He will be joining HealthSmart at ... and business performance. He defines strategic roadmaps by reimagining business processes—bridging the gap ...
(Date:5/21/2017)... Amarillo, Texas (PRWEB) , ... May 21, 2017 ... ... Feminism International Conference has brought together a cross-disciplinary group of scholars, policymakers, and ... Breastfeeding, Social Justice, and Equity is the third book from a ...
(Date:5/21/2017)... ... May 21, 2017 , ... ... been longer than six months since you've seen a dentist, it's time for ... year and getting x-rays once per year. , Dental checkups are a relatively ...
(Date:5/19/2017)... ... May 19, 2017 , ... When Kyle Busch graduates from ... will already appear on two major research studies that could impact the health of ... Matt Daggett, KCU alumnus and an orthopedic surgeon, alongside an international team trying to ...
Breaking Medicine News(10 mins):
(Date:5/18/2017)...  Bayer announced today that the latest research from ... the 53 rd Annual Meeting of the American ... in Chicago . ... liver and thyroid cancers, as well as lymphomas, and ... trial of copanlisib in patients with relapsed or refractory ...
(Date:5/10/2017)... May 10, 2017 Hologic, Inc. (Nasdaq: ... for the fiscal second quarter ended April 1, 2017 ... $1.84 increased 666.7% compared to the prior year period ... in a significant gain, while non-GAAP diluted EPS of ... or 3.8% in constant currency terms.  Excluding the effects ...
(Date:5/9/2017)... , May 9, 2017 Zimmer Biomet ... in musculoskeletal healthcare, today announced it has earned a ... of 2017" list. The Company was ranked among 500 ... Large Employers and Healthcare Equipment and Services. ... based on an anonymous, independent survey of over 30,000 ...
Breaking Medicine Technology: