Navigation Links
A Synthetic Molecule Instigates Cancer Cells To Self-Harm

Scientists have devised a method to outwit cancer cells and instigate them to self-harm, ultimately causing death of cancer cells. This novel discovery could unlock reliable// treatments for cancer.

This discovery works on the known principle that involves the activation of the body’s many defenses, to check the abnormal growth of cells; the way to achieve this is to get the faulty cells to kill themselves. This natural process, termed as apoptosis, involves he role of a protein called procaspase-3. When triggered, procaspase-3 changes into an enzyme called caspase-3, that causes the cells to die.

During cancer, this mechanism in the body is rendered defective, which is why the abnormal growth of cells carries on unchecked. Often the cancers are pretty strong to combat the natural defense forces in the body, and are stronger than the chemotherapy drugs.

But Paul Hergenrother, a chemist at the University of Illinois at Urbana-Champaign, has discovered a method to get the natural biological process, to go on unimpeded, which is to have a synthetic molecule that actually triggers apoptosis. For this, the team scrutinized 20,000 different compounds that portrayed the abilities to change procaspase-3 into caspase-3. This potent molecule was termed as PAC -1

PAC-1 was found to be able to obliterate many types of cancer cells, but its efficacy was based upon the levels of procaspase-3 in the body.

Quoting the words of Prof Hergenrother, "As such, the potential effectiveness of a compound such as PAC-1 could be assessed ... with a high degree of accuracy, and people with cancer could be pre-selected for treatment with a procaspase-3 activator based on the concentration of procaspase-3 in their tumor cells."
'"/>




Page: 1

Related medicine news :

1. New Study Will The Look Into The Effects Of Synthetic Steroids
2. Synthetic protein found to relieve arthritis symptoms in animal model
3. Synthetic Bone Tissue Could Be the Answer to Disfigurement Caused by Oral Cancer
4. Synthetic DNA Makes Better Hydrogels for Drug Delivery
5. Super Chow, Laced With Semi-Synthetic Vitamin E, Inhibited Spread of Cancer
6. Synthetic Chemicals May Trigger Breast Cancer
7. Synthetic Cannabinoid Could Improve Fertility in Smokers
8. Chemicals Used To Make Synthetic Color Can Cause Cancer And Permanent Blindness
9. New Molecule that can stop the growth of Viruses
10. Puberty may be due to GPR54 gene and KiSS-1 Molecule
11. Molecule responsible for muscle repair identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/19/2017)... ... August 18, 2017 , ... ... a transparent, verifiable database to help the cannabis industry move towards greater legitimacy. ... to deliver a faster technology with lower fees. Paragon will build a fully ...
(Date:8/19/2017)... ... August 19, 2017 , ... Yesterday, the President of the ... there are two sides. There are not two sides to hatred, bigotry, discrimination, and ... and prejudice, and the NPEIV stands against all forms of such hatred and discrimination ...
(Date:8/18/2017)... , ... August 18, 2017 , ... More than 20,000 ... Republic of Congo (DRC) thanks to an ambitious venture that conjoined the passions of ... the generous support of the Liberty community. These shoes will save lives from the ...
(Date:8/18/2017)... ... 18, 2017 , ... Mediaplanet today announces the launch of ... and highlighting the importance of proactive eye and ear health. The campaign focuses ... innovations in hearing aid technology. , In this issue, the American Speech-Language-Hearing ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... services to communities in east Texas, is launching a regional charity effort to ... Founded in 1991, the Pediatric Brain Tumor Foundation (PBTF) has raised nearly $30 ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... , Aug. 17, 2017 Bio-Ess Laboratories, LLC Chief Science ... antibody titer and present new data on Cell-Ess® Universal Titer ... Boston, MA August 21-25.  The Bioprocessing Summit convenes ... bioprocess challenges. ... Optimizer ...
(Date:8/15/2017)... OCEANSIDE, Calif. , Aug. 15, 2017  AOTI Inc. announced ... Advanced Oxygen Therapy Inc., has recently opened a New York City ... the ever-increasing usage of its unique Topical Wound Oxygen (TWO 2 ... approved by the Accreditation Commission for Health Care (ACHC) under the ... ...
(Date:8/8/2017)... 2017   Second-quarter ... (GAAP) loss per share from continuing operations ... increased 16 percent to $110 million ... percent to $161 million ... continuing operations increased 8 percent to $0.93 ...
Breaking Medicine Technology: