Navigation Links
A Synthetic Molecule Instigates Cancer Cells To Self-Harm

Scientists have devised a method to outwit cancer cells and instigate them to self-harm, ultimately causing death of cancer cells. This novel discovery could unlock reliable// treatments for cancer.

This discovery works on the known principle that involves the activation of the body’s many defenses, to check the abnormal growth of cells; the way to achieve this is to get the faulty cells to kill themselves. This natural process, termed as apoptosis, involves he role of a protein called procaspase-3. When triggered, procaspase-3 changes into an enzyme called caspase-3, that causes the cells to die.

During cancer, this mechanism in the body is rendered defective, which is why the abnormal growth of cells carries on unchecked. Often the cancers are pretty strong to combat the natural defense forces in the body, and are stronger than the chemotherapy drugs.

But Paul Hergenrother, a chemist at the University of Illinois at Urbana-Champaign, has discovered a method to get the natural biological process, to go on unimpeded, which is to have a synthetic molecule that actually triggers apoptosis. For this, the team scrutinized 20,000 different compounds that portrayed the abilities to change procaspase-3 into caspase-3. This potent molecule was termed as PAC -1

PAC-1 was found to be able to obliterate many types of cancer cells, but its efficacy was based upon the levels of procaspase-3 in the body.

Quoting the words of Prof Hergenrother, "As such, the potential effectiveness of a compound such as PAC-1 could be assessed ... with a high degree of accuracy, and people with cancer could be pre-selected for treatment with a procaspase-3 activator based on the concentration of procaspase-3 in their tumor cells."
'"/>




Page: 1

Related medicine news :

1. New Study Will The Look Into The Effects Of Synthetic Steroids
2. Synthetic protein found to relieve arthritis symptoms in animal model
3. Synthetic Bone Tissue Could Be the Answer to Disfigurement Caused by Oral Cancer
4. Synthetic DNA Makes Better Hydrogels for Drug Delivery
5. Super Chow, Laced With Semi-Synthetic Vitamin E, Inhibited Spread of Cancer
6. Synthetic Chemicals May Trigger Breast Cancer
7. Synthetic Cannabinoid Could Improve Fertility in Smokers
8. Chemicals Used To Make Synthetic Color Can Cause Cancer And Permanent Blindness
9. New Molecule that can stop the growth of Viruses
10. Puberty may be due to GPR54 gene and KiSS-1 Molecule
11. Molecule responsible for muscle repair identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... centers in the U.S., announced today its plans to open a flagship location in ... will occupy the former Rooms To Go store next to Office Depot in the ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... Wesley Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... Chapel is holding a treadmill relay – Miles by Moonlight to raise money for ... by donating $300 or more. , Teams will work together to keep their ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United ... year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and ... havens have extremely low property-tax rates, which contributes to the relatively lower cost ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... Oct. 5, 2017  In response to the ... and Maxillofacial Surgeons (AAOMS) released prescribing recommendations that ... be used as a first-line therapy to manage ... Recognizing the value and ... Paper "Opioid Prescribing: Acute and Postoperative Pain Management" ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... Fla. , Oct. 2, 2017  AllianceRx Walgreens ... company formed by Walgreens and pharmacy benefit manager Prime ... its new brand, which included the unveiling of new ... , as well as at a few other ... the new brand to patients, some of whom will ...
Breaking Medicine Technology: