Navigation Links
A Novel approach in Malaria treatment

A new treatment for malaria has been developed with the help of British scientists that could save several thousand of young lives in Africa. A system based on fluid// replacement for children suffering from malaria, has been developed by the Imperial College in London in collaboration with the Wellcome Trust Kenya Medical Research Institute Centre.

Approximately 80% of the lives of millions of kids, who die every year due to malaria, could be saved. 98% survival after treatment was reported in a trial of 88 children with malaria.

The treatment developed in an 8-year collaborative study is published in the journal PLOS Clinical Trials. The study revealed that fluid depletion was the major cause of occurrence of serious symptoms in Kenyan kids with malaria.

Previously, kids with severe malaria were not given extra fluids due to the fear of aggravation of brain swellings linked with the disease. The new treatment incorporates albumin, a protein that retains water inside the blood vessel, in resuscitation fluids given to children. In the two initial studies, less than 5% of the kids died who received albumin when compared to nearly 40% dying after receiving conventional treatment.

A new trial was carried out on 88 kids with severe malaria, in which, the kids were given either albumin solution or a plasma substitute called gelofusin. Though reduction in shock was seen in both the cases, only 2% of the kids who received albumin died when compared to 16% receiving gelofusion.

Researcher Dr Kathryn Maitland said: "The observation that treating very sick children with severe malaria with albumin infusion can reduce the mortality rate by over 80%, represents a major breakthrough towards improved treatment of this devastating illness.

"However, administration of fluid to children critically ill with malaria is contrary to prevailing practice, and albumin is currently not available in most African hospitals.
"It is absolutely essential that the results are reproduced in larger studies before we advise on any change in practice."

"The results of this trial support have gone some way to answering the question of whether this sort of supportive treatment saves lives and we are now seeking funding to set up a larger trial involving over 1,000 children in Ghana, Gambia and Kenya to confirm these findings," Maitland said.

Professor Brian Greenwood, of the London School of Hygiene and Tropical Medicine, said: "There was still much confusion about whether or not to give children with malaria fluids. The numbers in the trial are small, but this is an encouraging result which certainly should be followed up."
GYT
'"/>




Related medicine news :

1. Novel "CYCLOSPORINE CAPSULE FORMULATION" to be launched
2. Novel biopsy technique for prostate cancer
3. Novel computer model for breast cancer
4. Novel research on liver cancer
5. Novel way to fight cancer
6. Novel test for bowel cancer
7. Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
8. Novel Therapy for Chronic Problem
9. Blood Sugar Kept In Control By Novel Protein
10. Novel antibiotic dressing developed for improved wound healing
11. United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and Nutrition ... the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market ... can be easily incorporated into liquid products, while reducing costs to end users. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , ... mock evacuation of the facility as part of a disaster drill on October 3rd. ... EMS and Shelton City Emergency Manager, as well as the Connecticut Long Term ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob Lowe, ... in a new episode of "Success Files," which is an award-winning educational program ... investigates each subject in-depth with passion and integrity. , Sciatica occurs when the ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “America On ... Christian identity. “America On The Brink” is the creation of published author, William ... several great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)...  Commended for their devotion to personalized service, SMP Pharmacy ... one in the South Florida Business Journal,s 50 Fastest-Growing Companies, ... list, the national specialty pharmacy has found its niche.  To ... soon be honored by SFBJ as the 2017 Power Leader ... to receive his award in October, Bardisa said of the ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
Breaking Medicine Technology: