Navigation Links
A New Pill to Burn Away Unwanted Fat

US scientists claim to have devised a drug that can switch on a gene to burn body fat, offering hope of an exercise pill. //

And now pop a pill and burn away all the unwanted fat. The latest achievement of the scientists at The Salk Institute for Biological Studies, California in the US points in that direction.

Mice given the drug devised by them burned off fat, even when they did not exercise, and were resistant to weight gain despite a high-fat diet.

The Salk scientists assert though that the ultimate use of their drug would be to treat people at risk of obesity-related diseases like diabetes, rather than offer a "no-work six-pack" pill.

The drug mimics normal fat and chemically triggers a gene switch called PPAR-delta. Turning on this switch activates the same fat-burning process that occurs during exercise.

Lead researcher Dr Ronald Evans believes the same will occur in humans.

UK expert Dr Fredrik Karpe, from the Oxford Centre for Diabetes, Endocrinology and Metabolism, is hoping to test this in the near future.

Commenting on the work, he said: "There has never been a method to 'medically' switch on fat burning before.

"The finding that PPAR-delta co-ordinates this process, not only by switching on fat burning, but also to rebuild the muscle in a way making it more fit for fat burning, is of major interest, not least as a completely novel approach for the treatment of the metabolic derangements accompanying obesity."

Many teams have been studying the genetic pathways controlling how muscle builds up and is broken down in the body.

Tests on rodents earlier too had showed that manipulating these pathways can halt muscle wastage from disuse or disease.

At least three research groups said they had identified some of the genes responsible.

Alfred Goldberg and colleagues at Harvard University in the US and a phar maceutical company Regeneron said they had found genes called atrogin1 and muRF1 that were active during muscle wasting.

A team at Purdue University, Indiana, has been looking at a gene called erg1.

The drugs might mean that people with broken bones could avoid long and painful physiotherapy sessions to rebuild muscle strength.

Weaning people off respirators would also become easier as doctors could prevent wasting of the diaphragm.

National Aeronautics and Space Administration (NASA) of the US is also interested in the medicines because astronauts lose muscle mass on long missions.

Experts warn that although the drugs would maintain muscle size, they would not provide any of the other health benefits of regular exercise.

Professor Paul Greenhaff at Nottingham University in the UK who has been conducting similar research into muscle growth and wasting warned of the inherent potential for abuse in such drugs.

He said that the role of exercise had been underplayed.

"Contraction of the muscle itself is important. Exercise itself is the most highly potent stimulus of muscle growth. We must also look closer at nutrition as well."

Dr Julia Thomas at the Muscular Dystrophy Campaign said: "In order for this treatment to be truly beneficial it is important that muscle strength is also increased and future trials and research will be key in determining whether this is the case."

She said a pill to prevent muscle loss would unfortunately not be able to change the genetic cause of muscular dystrophy, but might slow down the disease progression.

"It is our hope that if this research becomes a workable drug the concentration of its use will be on serious medical conditions, such as muscular dystrophy, rather than for those desiring a 'gym in a bottle'."

Related medicine news :

1. Humans Found To Have The Ability To Block Unwanted Memories
2. Morning-After Pill At The Local Pharmacy Could Prevent Unwanted Pregnancies
3. U.S. Doctors Order Unwanted Medical Tests
4. Teenage Girls are Forced To Have Unwanted Sex
Post Your Comments:

(Date:11/29/2015)... ... November 29, 2015 , ... NewsWatch featured X-wing as ... available to consumers. Amanda Forstrom, a technology expert and special reporter for NewsWatch, conducted ... reality in the future. , It’s the future because flying cars are about to ...
(Date:11/29/2015)... ... , ... Effective immediately, every single IguanaMed scrub style will be available at ... offering a “Buy One Scrub Set, Get the 2nd Scrub Set 50% Off” for ... a discounted price. , IguanaMed’s mission is to outfit every healer around ...
(Date:11/28/2015)... ... ... at 6:00 a.m. EST until 11:59 p.m. EST, customers will be racing ... off orders $80 or more to free gifts with purchases, there will be a new ... e-commerce website for skin care and cosmetic needs, customers will save on already discounted prices. ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published ... that they are handling security in light of the recent terrorist attacks in Paris, ... attempt to stop an attack from reaching U.S. soil. Especially around special events that ...
(Date:11/27/2015)... ... 27, 2015 , ... Lizzie’s Lice Pickers just announced a special promotion that ... of their purchase of lice treatment product. In addition, customers will receive a complimentary ... spokesperson. “Finding lice is a sure way to ruin the holidays, so we encourage ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... DUBLIN , Nov. 25, 2015 /PRNewswire/ ... announced the addition of the "Global ... to their offering. --> ... "Global Brain Monitoring Devices Market 2015-2019" ... Research and Markets ( ) ...
(Date:11/25/2015)... , Nov. 25, 2015  Amgen (NASDAQ: ... License Application (BLA) with the United States ... ABP 501, a biosimilar candidate to Humira ® ... biosimilar application submitted to the FDA and represents Amgen,s ... Sean E. Harper , M.D., executive vice president ...
(Date:11/25/2015)... 2015  Linden Care, LLC, a retail specialty pharmacy ... patients suffering from chronic pain, said today that it ... Order (TRO) enjoining Express Scripts from unilaterally terminating the ... --> --> The company said ... options. --> --> ...
Breaking Medicine Technology: