Navigation Links
A New Gene to Contribute in Insulin Metabolism

blood sugar level. Via a complicated sequence of reactions it ensures that muscles and other organs absorb blood sugar. What is more, however, the cascade of insulin signals also determines size and number of the body cells during growth. Apparently, 'Titch' plays a key role in this shower of signals. 'The fruit fly larvae increase their weight 200-fold in the first three days after hatching,' Michael Hoch explains. 'If their 'Titch gene' has mutated, they grow visibly more slowly.' A series of additional observations support the thesis that 'Titch' is extremely important for the metabolism of insulin in drosophila. If there were a cytohesin with a similar function in mammals, this would, for instance, be of great interest for research into diabetes.

In parallel to Michael Hoch's research, Professor Michael Famulok produced an active substance that inhibits cytohesins, known as SecinH3. 'We fed this inhibitor to mice,' he explains. Unlike fruit flies, the rodents do not have just one cytohesin at their disposal, they have four. Professor Famulok wanted to find out whether they play a similar crucial role in the insulin metabolism of mice as 'Titch' does in the fly and discovered the following: 'Liver cells of the animals treated with SecinH3 reacted to insulin not nearly as strongly as they should.' Medical people know this effect: this insulin resistance is regarded as a warning signal for the onset of Type II diabetes.

Six million people suffer from this type of diabetes in Germany alone. It is triggered by an unhealthy diet and lack of exercise, and the tendency is rising. Michael Famulok now thinks new drugs are on the cards. 'There is a class of switch molecules which are activated by cytohesins. This activation is apparently necessary to pass on the signals. If we manage to stimulate the switch molecules with a suitable active substance, we might possibly be able to thereby reverse the resistance to insulin.' A new method described by Mich
'"/>




Page: 1 2 3

Related medicine news :

1. Railway Station Contributes to Create Awareness on AIDS
2. Fruits And Vegetables Contribute To Memory
3. Record Number of Countries Contributed to UNFPA in 2005
4. Blood Transfusion May Have Contributed Towards Hepatitis C
5. Parental Domestic Violence Contributes To Adolescent Depression
6. Increase in Waist Size Contributes To Increased Risk of Heart Disease
7. Abnormal Glucose Metabolism May Contribute to Chronic Nerve Disorder
8. Stereotypes Contribute to Older Men Seeking, Receiving Depression Care Less Frequently
9. Outbreaks of Whooping Cough Contributed by Vaccine Exemptions
10. China Contributes Billions to Root Out Animal Diseases
11. Smog in Warm Weather may Contribute to Stroke Risks in Elderly: Study
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Gene Contribute Insulin Metabolism

(Date:4/18/2015)... April 18, 2015 "I recognized the ... in healthcare facilities," said an inventor from Cincinnati, Ohio. ... system." , He developed the Slyde Door to offer ... in healthcare facilities. It provides convenient storage space for ... more stretchers available for patients. , This offers ...
(Date:4/18/2015)... 2015 Lowcostcarinsuranceprice.com has released a new ... on auto insurance prices . , Drivers ... vehicle theft may have to pay more for auto ... insurance policies can also offer protection against vehicle theft. ... compared online on a single website: http://lowcostcarinsuranceprice.com/ ...
(Date:4/18/2015)... April 18, 2015 In the past ... couple of changes. , "We had to run maintenance ... needed changes," said Jennifer Ramirez, the PR Director. "It ... to say that we are back on track after ... the process of changing phone systems which has not ...
(Date:4/18/2015)... “ ArcAngel ” was featured on NewsWatch as part of ... and coolest applications on the market for iOS, ... technology expert, conducted the app review and shared with viewers ... a turbulent world, people may find themselves in dangerous situations ... first move, but some situations can be avoided if there ...
(Date:4/17/2015)... John Evans, a Gardant affordable assisted living ... 2 p.m. to 3 p.m. on April 24. , ... in Pekin, Illinois, serves older adults of all incomes, ... maintain their independence. , Becky Baker will entertain guests ... served during the luau. , For more information, call ...
Breaking Medicine News(10 mins):Health News:High Rates Of Car Theft Can Have An Impact on Auto Insurance Prices! 2Health News:TheBeautyPlace.com Temporary Number Available 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2
... Superior Side-Effect Profile Earns Vesicare Gold Standard Status Over, ... ... Decision Resources, WALTHAM, Mass., April 3, 2008 ... focusing on,pharmaceutical and healthcare issues, finds that a drug,s effect on ...
... 32 Dallas-area students will be participating in the American ... Program. The program is held in conjunction with the ... Anatole Hotel. , The students are from the High ... School, and the Business and Management Cluster School. The ...
... Medical Mutual of Ohio,announced the acquisition of Premier ... network headquartered in Columbia,South Carolina., PHS was ... Palmetto,Health., The acquisition expands Medical Mutual,s presence ... Carolina Care Plan, a Columbia-based health,plan that serves ...
... N.C., and SAN DIEGO, April 3, 2008 ... and development organization, and,Advanced Targeting Systems, Inc. ... a new strategic alliance focused on development,and ... for chronic,pain. Advanced Pain Therapeutics LLC (APT), ...
... ,MemorialCare is joining forces with its physician partners ... to the hard hits health care,providers have been ... Medi-Cal reimbursement cuts to physicians, as well as ... inpatient,services., In efforts to continue to build ...
... ANA, Calif., April 2, 2008 Grubb &,Ellis Healthcare ... in Lakeland, Fla., Located at 3035, 3037, 3131, ... complex is comprised of four identical buildings. Each,building has ... square feet. Built in 1996 and 1998 on approximately ...
Cached Medicine News:Health News:Astellas/GlaxoSmithKline's Vesicare Has Advantages Over Pfizer's Detrol LA/Detrusitol XL in Reducing Episodes of Urge Urinary Incontinence 2Health News:Cato Research Ltd. and Advanced Targeting Systems, Inc. Partner to Develop SP-SAP for Chronic Pain 2Health News:Cato Research Ltd. and Advanced Targeting Systems, Inc. Partner to Develop SP-SAP for Chronic Pain 3Health News:MemorialCare Joins Forces with Physician Partners to Advocate for a Balanced, Fiscally Responsible Healthcare System 2Health News:Grubb & Ellis Healthcare REIT Acquires Vista Professional Center in Lakeland, Fla. 2Health News:Grubb & Ellis Healthcare REIT Acquires Vista Professional Center in Lakeland, Fla. 3Health News:Grubb & Ellis Healthcare REIT Acquires Vista Professional Center in Lakeland, Fla. 4
(Date:4/17/2015)... 2015  AbbVie Inc. ("AbbVie") (NYSE / CHX / Euronext ... the expiration of its exchange offer to acquire all of ... 5 p.m., New York City time, ... 2015, AbbVie also voluntarily withdrew its initial Notification and Report ... provide the FTC with additional time to review the proposed ...
(Date:4/17/2015)... Inivata, a Cambridge, England -based ... the 2015 American Association for Cancer Research (AACR) Annual Meeting ... and a poster presentation. Michael Stocum , CEO ... nd . The presentation, entitled Monitoring the ... part of a session on Recent Advances in Diagnostics ...
(Date:4/17/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/lmsnqn/medical_equipment ... Equipment Rental and Leasing - Global Strategic Business Report" ... analyzes the worldwide markets for Medical Equipment Rental and ... analytics for the US, Japan , ... Annual estimates and forecasts are provided for ...
Breaking Medicine Technology:AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 2AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 3AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 4Inivata Co-founder Nitzan Rosenfeld to Present at AACR Annual Meeting 2Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2
For the quantitative in vitro determination of Carbamazepine in human serum...
For the quantitative in vitro determination of Phenobarbital in human serum....
Determination of the Thrombin Time by STA Analyzers. Freeze-dried human thrombin (1.5NIH units/mL) with calcium....
Determination of Activated Partial Thromboplastin Time (APTT) by STA Analyzers. Cephalin reagent with particulate (silica) activator....
Medicine Products: