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A New Drug That Could Revolutionize Management Of Heart Disease

and repairs the damaged enzyme. And as the number of free radicals increases, the drug starts working harder," says Dr. Schmidt. The results have been published in the Journal of Clinical Investigation and the September issue of Nature Reviews/Drug Discovery.

Dr. Schmidt, together with clinical and basic science colleagues, is creating a new research centre at Monash with the aim of challenging orthodox thinking on heart disease and stroke.

"Vascular diseases are the number one cause of death worldwide. Yet we don't know enough about the causes to reliably identify and treat cases, let alone prevent these diseases," he says. "In up to 95 per cent of cases, the root causes of vascular diseases are still unknown. So clinicians have to rely on 'lifestyle' indicators and 'risk factors' such as high blood pressure and high cholesterol.

"However, not all people with high blood pressure or high cholesterol experience heart attack or stroke At the same time, many people without any apparent risk factors have unexpected heart attacks and strokes. We need a revolution in vascular diagnosis, treatment and prevention. This discovery is an important step along the way."

Source-Eurekalert
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