Navigation Links
A New Breed Of Mice Might Hold The Key For Depression Treatment

A new research has been published in the journal Nature Neuroscience, states that a new breed of mice, called ‘cheerful mouse’ might hold the key for treatment of// clinical depression.

The researchers had explained that TREK-1 is a gene that might affect transmission of serotonin in the brain. They explained that serotonin is known to play an important role in mood, sleep and sexuality. The researchers had conducted their research by breeding mice without the gene TREK-1, and were able to create a depression-resistant strain.

"Depression is a devastating illness, which affects around 10% of people at some point in their life," says Dr. Guy Debonnel an MUHC psychiatrist, professor in the Department of Psychiatry at McGill University, and principal author of the new research. "Current medications for clinical depression are ineffective for a third of patients, which is why the development of alternate treatments is so important."

Mice without the TREK-1 gene ('knock-out' mice) were created and bred in collaboration with Dr. Michel Lazdunski, co-author of the research, in his laboratory at the University of Nice, France. "These 'knock-out' mice were then tested using separate behavioural, electrophysiological and biochemical measures known to gauge 'depression' in animals," says Dr. Debonnel. "The results really surprised us; our 'knock-out' mice acted as if they had been treated with antidepressants for at least three weeks."

This research represents the first time depression has been eliminated through genetic alteration of an organism. "The discovery of a link between TREK-1 and depression could ultimately lead to the development of a new generation of antidepressant drugs," noted Dr. Debonnel.

According to Health Canada and Statistics Canada, approximately 8% of Canadians will suffer from depression at some point in their lifetime. Around 5% of Canadians seek medical advice for depression each year; a figure that has almost doubled in the past decade. Figures in the U.S. are comparable, with approximately 18.8 million American adults (about 9.5% of the population) suffering depression during their life.

Source: EurekAler.
'"/>




Related medicine news :

1. New Breed Cats Marketed
2. Breeding Mosquitoes Soon to be a Criminal Offence
3. AIIMS Campus - A Breeding Ground for Mosquitoes
4. Breeding success by delving into the honey bee sex gene
5. Public Urged To Prevent Mosquito Breeding
6. Anemia Treatment for Cancer Patients Might Not be a Good Idea.
7. Tomatoes Might Inhibit the Development Of Prostate Cancer
8. Mad Cow Disease Might Be Linked to Blood Transfusions
9. Strategies That Might Lower Blood Pressure Questioned
10. Factors That Might Increase The Risk Of Schizophrenia
11. A Drug That Might Relieve Chronic Cough
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/21/2017)... MALO, FRANCE (PRWEB) , ... January 21, 2017 , ... ... of the Indian Ocean, isolated from the rest of the world with ZANZIBAR SHOWER ... East Africa, Phytocéane used key ingredients, Virgin Coconut Oil and moisturizing vegetal coral to ...
(Date:1/21/2017)... ... January 21, 2017 , ... Northern California Medical Associates (NCMA) ... their multi-specialty medical group. The dermatology practice provides general dermatologic treatment, outpatient surgery, ... add this excellent dermatology practice to our group’s medical services,” explains NCMA CEO, ...
(Date:1/21/2017)... , ... January 21, 2017 , ... In the United ... individuals experience the freedom of recovery, they often feel shame for having struggled with ... stress disorder (PTSD). In the workshop, “Rising Strong in Life After an Eating Disorder” ...
(Date:1/20/2017)... ... ... ADA Portable Motion Trek BP 300 Lift. Built for durability, this pool lift is easy ... wheeled out of the way and stored when not in use. It is freestanding and ... from customers into specific enhancements and created a new product that is built directly on ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... bible in homes across the world. Yisrayl says this generation is a time like no ... to turn to the Bible. , Yisrayl says he does not want to sound like ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Many patients don,t ... their medication when a pharmacy just a few blocks ...  To alleviate this problem Medicationdiscountcard.com has created ... see exactly how much their medication will cost at ... Easy Medicationdiscountcard.com takes ...
(Date:1/19/2017)... Jan. 19, 2017 Accuray Incorporated (Nasdaq: ... TomoTherapy® Systems continue to set the bar for excellence ... composite overall user satisfaction rating among radiation treatment delivery ... MD Buyline Market Intelligence Briefing™. The most recent ratings ... ratings among industry peers for 11 of the past ...
(Date:1/19/2017)... , Jan. 19, 2017 ViewRay, Inc. (Nasdaq: ... federal institution supporting research in Germany ... patient treatments at the University Clinic Heidelberg as part ... The MRIdian Linac program will be headed by Medical ... heads radiation oncology at the German Cancer Research Center ...
Breaking Medicine Technology: