Navigation Links
A New Approach In Treatment Neurogenic Detrusor Overactivity In Children

Many reports have dealt with the outcome of botulinum-a toxin (BTX-A) detrusor injections in patients with neurogenic or nonneurogenic detrusor overactivity. BTX-A detrusor injections have been described in adult// patients with neurogenic detrusor overactivity due to spinal cord injury.

Researchers from Germany were able to carry out the same experiments successfully in children with a neurogenic bladder. After many reports of this “wonder drug,” several questions have arisen, including what this injection treatment means for neurourologic patients in the longer term; whether bladder function changes after repeated BTX-A injections, and whether this procedure has a proper place in the treatment algorithm of young patients with neurogenic bladder. In an extension of their previous studies, the authors, set out o assess the long-term success of treatment with repeated botulinum-A toxin (BTX-A; Botox) injections into the detrusor muscle for neurogenic detrusor overactivity in children.

In their study published in the October issue of Urology, the researchers reviewed the charts of 10 children (average age at first injection 11.2 years) with neurogenic detrusor overactivity who had received at least three BTX-A detrusor injections; four had received five or more injections. The total dose of BTX-A was 85 to 300 U. They measured the urodynamic outcomes 6 months after each injection and compared the results after the first injection with the results after the third and fifth injections (in the children who had five or more injections).

The relative changes - each in comparison with the value before injection therapy - after the first versus the fifth injection were as follows: the reflex volume increased by 81% versus 88%, maximal detrusor pressure decreased by 7% versus 39%, maximal cystometric bladder capacity increased by 88% versus 72%, and bladder compliance showed no change at the 6-month follow-up visit after the first injection a nd an increase of 109% after the fifth injection. The results after the third injection were generally similar to those after the fifth injection. No major side effects occurred.

Patients with difficult bladder conditions refractory to anticholinergic drugs have traditionally undergone immediate surgical procedures, such as bladder augmentation. However, according to this new study, BTX-A detrusor injection offers a reliable alternative and protects some of those difficult-to-treat patients for years.
'"/>




Related medicine news :

1. New Dietary Approach To Manage Kidney Stones
2. Approaching through Telemedicine benefits patients
3. Gel Offers A More Targeted Approach
4. New Cost Effective Approach To Promote Sun Protection
5. Treatment Of Brain Aneurysms By A New Non-Surgical Approach
6. A New Diagnostic Approach To Pediatric Interstitial Lung Disease
7. Lazy Eye Can Be Effectively Treated By New Approach
8. Novel Approach to Identify Protein Links with Genetic Disorder
9. NHS To Be Reformed By Using A Hybrid Approach
10. Two-In One Approach To Prevent Incontinence After Prolapse Surgery
11. Women Afflicted With Dry Eyes As They Approach Menopause
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... May 31, 2016 , ... Fire Door Solutions, ... joined the Fire Door Solutions’ team. Keith will serve Fire Door Solutions ... in-field re-labeling. He will be instrumental in developing educational curriculum and leading ...
(Date:5/31/2016)... ... 31, 2016 , ... More than 80 representatives of the Hepatitis B ... Cancer Foundation held an event on National Hepatitis Testing Day outside of Philadelphia City ... the leading cause of liver cancer. , Foundation leaders and the citywide coalition they ...
(Date:5/31/2016)... TEXAS (PRWEB) , ... May 31, 2016 , ... ... live in Greater Houston Healthconnect’s (Healthconnect) regional health information exchange, which enables physicians ... medical records for their patients from other participating organizations in the exchange. SJMC’s ...
(Date:5/31/2016)... ... May 31, 2016 , ... When ... he knew it was something that contractors should have at their disposal on ... gets,” says Butch, CertainTeed’s Director of Contractor Programs. , As a result, ...
(Date:5/31/2016)... ... May 31, 2016 , ... Spartan Bioscience today introduced ... portability and convenience. , The Cube is exceptionally small—it takes up the space ... fits easily into any space, whether in a hospital, doctor’s office, or pharmacy. ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... According to a new market ... by Type (Human, Animal Pathology), by End User (Pharmaceutical ... - Global Forecasts to 2021", published by MarketsandMarkets, studies ... of 2016 to 2021. This market is expected to ... Million in 2016, at a CAGR of 12.1%. ...
(Date:5/31/2016)... May 31, 2016 Aloe vera ... food, cosmetics and pharmaceuticals, with global volume to surpass ... 1.6 Bn. Demand for aloe vera extracts ... yogurts will continue its upward momentum in 2016 as ... boost positive sentiment on aloe vera, with wide-ranging applications ...
(Date:5/31/2016)... , May 31, 2016 ... World Health Assembly zur Eliminierung von viraler Hepatitis ... Mitgliedsstaaten eine historische Verpflichtung eingegangen, virale Hepatitis bis ... . World Health Assembly haben sich die ... bzgl. viraler Hepatitis (Global Viral Hepatitis Strategy) zu ...
Breaking Medicine Technology: