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A Mushroom Extract May Impact the Body’s Immune Syste

ectrometry (MS). Statistical analyses of low- and high-resolution MS data were cross-validated to determine whether changes in immunologically relevant proteins occurred that were attributable to treatment with the mushroom extract.

Results Statistical analysis of the spectra showed significant differential post-translational modification or expression of proteins, in the range of 1-30 kilodalton (kDa – a unit of measure of the atomic mass of the proteins), in the treated sets of cell cultures, as compared to untreated, negative control samples. Many immunologically relevant proteins, including many known to regulate immune responses, fall within the 1-30 kDa range.

Conclusions The findings from this research study suggest that protein-bound, polysaccharide-rich fractions of Trametes versicolor PSK may modulate the post-translational modification or expression of proteins in healthy human immune cells. The next step is to extract and sequence the proteins of interest to determine their specific function in immune cells. The results invite further research to determine how selected extracts of medicinal mushrooms may be effective in strengthening the body’s immune system against diseases, such as cancer.

(Source: Newwise)
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