Navigation Links
A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity

f years of evolutionary history, an indication that it performs a biologically important function. But sometime after the human lineage diverged from its last common ancestor with chimpanzees 5 to 7 million years ago, HAR1 began to change rather dramatically.

"We found 18 differences between chimps and humans, which is an incredible amount of change to have happened in a few million years," Pollard said.

The researchers obtained preliminary evidence that HAR1F was active in the brain. Around that time, Pierre Vanderhaeghen, a neuroscientist at the University of Brussels, visited UCSC to give a seminar. Salama convinced him to include the new gene in a set of experiments he was planning, which would screen for active genes in a series of human embryonic brain sections.

"I had a half-hour meeting with him and gave him a DNA probe for HAR1 to take back to Belgium. I didn't hear anything for a few months, and then I got an e-mail from him saying that it gave a really interesting pattern of expression in the brain," Salama said.

HAR1F was first detected at seven and nine gestational weeks in the part of the embryonic brain that gives rise to the cerebral cortex. In subsequent experiments, collaborators in France looked at the corresponding gene in another primate, a macaque, and found a very similar pattern of expression in the developing macaque brain.

Unlike most known genes, HAR1F does not encode instructions for making a protein to carry out its function. Researchers are discovering a growing number of such "noncoding" genes, many of which produce functional RNA molecules. HAR1F appears to be a novel type of RNA gene, Salama said.

In the typical process by which genes are expressed or activated, the gene's DNA sequence is transcribed to produce a messenger RNA molecule, which then guides the synthesis of a specific protein. The encoded protein carries out the gene's function. Some genes, however,
'"/>




Page: 1 2 3 4

Related medicine news :

1. Human Genome Project Achieves Technological Triumph
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. Human gene number increases
4. Scientists found ancient Human Germ Killer
5. New standards for Human Research Safety
6. Human wasting disease linked to a gene
7. The Human Mad Cow Case
8. Human Growth Hormone Found To be Dangerous For Human Use
9. Human Antibody That Can Block SARS
10. Human immunity system can battle HIV.
11. Two New Human Papilloma virus (HPV) vaccines to prevent cervical cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Human Brain Gene Could Hold Clues The Evolution Brain Capacity

(Date:8/31/2014)... 31, 2014 Just in time for Washington’s ... only wild, sustainable Alaska Salmon, award winning chowder ... Duke's Green Lake location , Sunday, September 28, 2014 ... sample several ethnic salmon BBQ culinary delights. Live music will ... from Hawaii, Puerto Rico and Mexico will be featured. ...
(Date:8/31/2014)... Recently, BambooIndustry.com, one of the most popular suppliers of ... of bamboo veneers . Additionally, it has deiced offer ... high quality products. The promotion will last from today until ... its top quality veneers are hot in the global market. ... bamboo veneers. All these items are made according to our ...
(Date:8/31/2014)... Mesa, AZ (PRWEB) August 31, 2014 ... in Mesa, Arizona, prescribes sublingual immunotherapy to help his ... includes tree nut allergies. Dr. Agren said that it ... nut-based foods and, in many cases, restored peace of ... can lead to a host of symptoms, including rashes, ...
(Date:8/31/2014)... With years of hard work, Delta has now ... machines. Recently, the company has updated its wheel loader ... loaders. All these items are guaranteed to be great. Additionally, ... , It is true that all items in Delta’s ... machine specialists. The firm is making full efforts to help ...
(Date:8/31/2014)... (PRWEB) August 31, 2014 1Heart Caregiver ... Clarito and brain fitness expert Tee Barr conducted a ... Ventura City. Activities Director Virginia Ayala and Social Services ... and patients attend this brain fitness session. , Research ... and slowing down the development of dementia and memory ...
Breaking Medicine News(10 mins):Health News:Seattle Seafood Restaurant Duke's Chowder House on Green Lake Will Celebrate The Long Anticipated Indian Summer With First Annual Sizzling BBQ Salmon Tasting Event. 2Health News:High Quality Bamboo Veneers from Bambooindustry.com Receive International Attention 2Health News:Family Allergy Clinic Announces Q4 2014 Release of Oral Drops for Tree Nut Allergies 2Health News:Family Allergy Clinic Announces Q4 2014 Release of Oral Drops for Tree Nut Allergies 3Health News:Delta Updates Its Wheel Loader Assortment With A Lot Of Cheap Used Cat 966 Loaders 2Health News:1Heart Caregiver Services Director Randy Neil Clarito Brings Brain Fitness Education to Victoria Care Center Ventura 2Health News:1Heart Caregiver Services Director Randy Neil Clarito Brings Brain Fitness Education to Victoria Care Center Ventura 3Health News:1Heart Caregiver Services Director Randy Neil Clarito Brings Brain Fitness Education to Victoria Care Center Ventura 4
... Georgia Tech Research Institute (GTRI) have developed a sensor ... to asthma attacks. Worn in the pockets of a ... causes of asthma attacks. , We are investigating whether ... see what was going on environmentally when the attack ...
... The use of regular, long-term aspirin and non-steroidal ... cancer, according to a study published in Gastroenterology ... (AGA) Institute. However, the use of aspirin for chemoprevention ... doses that are higher than recommended over a long ...
... prescription drugs so that the system more closely resembles ... drug use without altering patients out-of-pocket spending, health plan ... RAND Corporation study. , Researchers propose that consumers pay ... a years worth of medicine for each prescription they ...
... need to be monitored closely, study says , , TUESDAY, Jan. ... of patients with kidney or liver cancer also increases the ... Nexavar (sorafenib) need to be carefully monitored and treated, said ... online issue of Lancet Oncology . , Nexavar is ...
... Medicine (IGM) at Johns Hopkins will join other national ... ambitious effort that will involve sequencing the genomes of ... most detailed and medically useful picture to date of ... in creating a map of common DNA variation in ...
... Same-sex couples are just as committed in their ... have studied the quality of adult relationships and ... couples in same-sex relationships are not as committed ... as psychologically healthy. , These results are from ...
Cached Medicine News:Health News:Investigating causes of asthma attacks: New sensor system monitors environmental exposure 2Health News:Regular, long-term aspirin use reduces risk of colorectal cancer 2Health News:Researchers propose consumers buy yearly 'drug licenses' as new way to pay for prescriptions 2Health News:Researchers propose consumers buy yearly 'drug licenses' as new way to pay for prescriptions 3Health News:Liver Cancer Drug Raises Blood Pressure 2Health News:Johns Hopkins to participate in 1000 Genomes Project 2Health News:Equal level of commitment and relationship satisfaction found among gay and heterosexual couples 2Health News:Equal level of commitment and relationship satisfaction found among gay and heterosexual couples 3
(Date:8/29/2014)... 29, 2014 Diseases largely eradicated in ... are returning. Measles was declared eliminated in 2000, yet ... of August 15—the highest incidence in 20 years. In ... declared whooping cough a problem of "epidemic proportions." ... and dying from these preventable diseases—in part because some ...
(Date:8/29/2014)... 29, 2014  Abaxis, Inc. (NasdaqGS: ABAX ... and consumables to the medical, research and veterinary markets, ... Chief Executive Officer, will present at the CL King ... Tuesday, September 9, 2014 at 12:30 p.m. ET. The ... Hotel in New York City . ...
(Date:8/29/2014)... -- , Industry professionals and media ... taking place in real-time at CPhI Worldwide  ... UBM Live , announces the launch of #CPhIChat ... its kind global industry-wide Tweetchat for pharma professionals ... to stimulate conversations on key industry issues and ...
Breaking Medicine Technology:Vaccines at the Crossroads: Outbreaks On the Rise Across America 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 3Abaxis, Inc. to Present at CL King's 12th Annual Best Ideas Conference 2014 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 3
... Unilife Corporation ("Unilife" or "Company") (NASDAQ: ... the three months ended September 30, 2011 (Fiscal Year ... Following the commencement of initial supplies of ... progressively increased production capacities at its York, PA facility. ...
... Calif., Nov. 9, 2011 diaDexus, Inc. (OTC Bulletin Board: ... development and commercialization of patent-protected in vitro diagnostic ... results for the third quarter of 2011. Total ... million, representing 38% growth over total revenues of $3.2 million ...
Cached Medicine Technology:Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 2Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 3Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 4Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 5Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 6Unilife Corporation Announces Financial Results for Fiscal Year 2012 First Quarter 7diaDexus, Inc. Reports 38% Year-Over-Year Revenue Growth for 2011 Third Quarter 2diaDexus, Inc. Reports 38% Year-Over-Year Revenue Growth for 2011 Third Quarter 3diaDexus, Inc. Reports 38% Year-Over-Year Revenue Growth for 2011 Third Quarter 4diaDexus, Inc. Reports 38% Year-Over-Year Revenue Growth for 2011 Third Quarter 5diaDexus, Inc. Reports 38% Year-Over-Year Revenue Growth for 2011 Third Quarter 6
... Central Blood Pressure/Pulse Wave Velocity System is an ... system enables the measurement of the velocity of ... The velocity of the pressure wave along the ... artery. This system is most commonly used to ...
Used to remove wrinkles from sections and for reorientating embedded tissue....
Liquichek Blood Gas Plus CO-Oximeter Control (Radiometer) is a combination control for use in monitoring the performance of blood gas, ion-selective electrode, biosensor and CO-Oximeter (Radiometer) ...
Liquichek Blood Gas Plus E Control is an aqueous product used to monitor the measurement of pH, pCO2, pO2 and electrolytes. Available in four levels....
Medicine Products: