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A Better Way to Deliver Cancer Drugs

plaining that an implant could be placed within an area of the body without the need for surgery--ideal for treating prostate, breast, and other forms of cancer. "It's a liquid gel at room temperature, and it forms an implant once it is injected into the body and reaches 37 degrees Celsius," she says.

For the past three years, the team has been testing the system on different strains of mice to determine the efficacy of certain drug concentrations. Two weeks ago the researchers received funding to carry out a series of toxicity studies on mice before beginning human testing. Christine Allen, codeveloper and University of Toronto chemical engineer, says the film has been designed to be flexible enough that it won't puncture internal organs. It's also completely biocompatible. "One of the problems with past systems like this is they're seen as foreign by the body, and tissue grows around it," Allen explains. In this situation, called fibrous encapsulation, the surrounding tissue can often prevent proper drug release or keep the drug from reaching the tumor. "We haven't had this problem," she says.

Source-Bio-Bio Technology
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