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A Basic Symptom Index For Early Detection Of Ovarian Cancer

An index comprising of the basic symptoms associated with ovarian cancer may aid clinicians detect ovarian cancer in its early stages, according to a new study.// This index is expected to serve as a rapid, cost-effective screening tool.

The details of this study is published in the January 15, 2007 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, the study reveals that early ovarian cancer may be distinguished from other causes by a specific set of symptoms and their frequency and duration.

Physicians generally consider ovarian cancer to be a "silent killer." That is, it develops asymptomatically or with symptoms easily attributable to benign causes until diagnosed late in the course of disease and well after a cure is likely. There is no effective screening test to detect early stage disease in the general population or even high-risk groups. Consequently, no professional gynecology association or public health agency recommends routine screening. The lack of a recognized index of early clinical signs and symptoms,delays diagnosis until disease has advanced. These factors combine to make ovarian cancer one of the deadliest malignancies in the world.

Recent evidence suggests that early-stage symptoms may be recognizable and could be used to develop a symptom index for early disease. Led by Barbara A. Goff, M.D. of the University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center in Seattle, researchers compared the clinical history of women at high risk for developing ovarian cancer and women already diagnosed with ovarian cancer to develop a basic symptom index to screen for ovarian cancer.

They found "that a relatively simple evaluation of symptoms of recent onset and significant frequency" was sufficient to be a potential screening tool. Any complaint of pelvic/abdominal pain, increased abdominal size/bloating,
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