Navigation Links
“Provenge”, Dendritic cell vaccine for Prostate Cancr

An experimental dendritic vaccine has shown significant prognosis and extension of lifetime of men with prostate cancer. The vaccine Provenge is based on dendritic cells, which help the immune system recognize tumors. // “If these results are true, this represents the first proof of principle of a dendritic cell vaccine altering the natural history of a solid tumor”, says Philip Kantoff, Chief of solid tumor oncology at the Dana-Farber Cancer Institute in Boston.

Provenge carries the patients own dendritic cells engineered to express a protein found on about 95% of prostate cancer cells. It is one of more than 15 vaccines in trials for a range of cancers, including lymphoma, melanoma, breast, lung and colorectal cancers, but the first to increase lifespan in advancer cancer patients.

There are also questions about which cells are antigens to use in vaccines and the mode and frequency with which they should be administered. For example, mature dendritic cell vaccines seem to produce the best immune response when given either subcutaneously or intradermally, but not intravenously. Researchers are trying to determine whether vaccines will be need to be designed for specific cancers, or whether a universal vaccine could produce a robust immune response.

The provenge trial has raised several questions of its own: 34% of men given provenge, compared with 11% on placebo, were alive three years on, and lived 4.5 months on average longer. “Because of this, we were all somewhat pleasantly surprised that Provenge showed a survival benefit, says E. Roy Berger, director of the Prostate Cancer Consultation and Treatment service in East Setauket, New York.

“Cancer vaccines prime the immune system to attack cancer, a slower, more indirect process,’ he says. This may mean that survival, and not time to progression is a better measure of efficacy for cancer vaccines, Berger suggests.

Source: Nature Medcine
'"/>




Page: 1

Related medicine news :

1. New hope for cancer victims – will vaccine cure the deadly bug
2. New vaccine helps allergy and asthma patients
3. Man against HIV – new vaccine ready for human trials
4. New vaccine helps allergy and asthma patients
5. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
6. HIV did not arise from polio vaccine
7. Double impact vaccine
8. High Demand for a child vaccine
9. A new vaccine for leukemia
10. Shortage of MMR vaccine
11. Anthrax vaccine produced
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/17/2017)... ... 17, 2017 , ... Peoples Health is pleased to announce ... Dec. 1, 2016. Peoples Health, a Metairie-based Medicare Advantage company, serves more than ... to our provider network, and the addition will benefit our members in the ...
(Date:1/17/2017)... ... January 17, 2017 , ... A prescription medication bottle, pocket knife, luggage and ... to Cradle Product Design Challenge , the Cradle to Cradle Products Innovation Institute ... design challenges scheduled to run through early 2018. The challenges are presented by the ...
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... Neil H. ... financial planning assistance to communities throughout the region, is launching a charity drive to ... disease is by far the deadliest killer in America, and is responsible for 1 ...
(Date:1/17/2017)... ... January 17, 2017 , ... SC&H Group, a leading ... a Principal in its IT Advisory Services practice . Rossi is the third ... market demand for strategic IT guidance grows, and the practice continues to expand.     , ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... and eliminate cyber threats in real-time, today announced a strategic partnership with ... Selangor, Malaysia. Joining other Seceon partners, TechLab Security has become a strategic partner ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... -- Edwards Lifesciences Corporation (NYSE: EW ), the ... and critical care monitoring, plans to announce its operating ... the market closes on Wednesday, February 1, 2017, and ... that day to discuss those results. To ... (201) 689-8037.  For 72 hours following the call, an ...
(Date:1/17/2017)... PUNE, India , Jan. 17, 2017  Market Research Future ... Global Endoscopy Devices Market is expected to reach USD 33.6 million ... 2016. Market Highlights ... The Global Endoscopy Devices Market has been examined as ... rate. Globally there is huge demand for endoscopy device in various ...
(Date:1/17/2017)... Research and Markets has announced the addition of the ... offering. ... global fluoropolymer market in the healthcare industry to grow at a ... Fluoropolymer Market in the Healthcare Industry 2016-2020, has been prepared based ... report covers the market landscape and its growth prospects over the ...
Breaking Medicine Technology: