Navigation Links
“Erectile Dysfunction” Drugs Heighten Natural Anti-Cancer Activiy

Sildenafil and other “impotence drugs” that boost the production of a gassy chemical messenger to dilate blood vessels and produce an erection now also show promise in unmasking// cancer cells so that the immune system can recognize and attack them, say scientists at the Johns Hopkins Kimmel Cancer Center.

Tests at Hopkins on mice with implanted colon and breast tumors showed that tumor size decreased two- and threefold in sildenafil-treated animals, compared to mice that did not get the drug. In mice engineered to lack an immune system, tumors were unaffected, proof of principle, the scientists say, that the drug is abetting the immune system’s own cellular response to cancer.

In a report published in the Nov. 27 issue of the Journal of Experimental Medicine, the Hopkins team says boosted levels of the chemical messenger nitric oxide appear to dampen the effects of a specialized cell that diverts the immune system away from tumors, allowing swarms of cancer-attacking T-cells to migrate to tumor sites in the rodents.

Lab-grown cancer cells treated with sildenafil showed similar results, as did tissue samples taken from 14 head and neck cancer and multiple myeloma patients.

Sildenafil, marketed under the trade name Viagra, is one of a class of drugs used to treat erectile dysfunction in millions of men, and in recent years, its ability to stimulate the production of NO has been investigated by experts in diseases linked to the activity of blood vessels and blood components.

The new Hopkins study homes in on a tactic used by cancers to avoid detection by the immune system by turning elements of that system to its own advantage, says Ivan Borrello, M.D., assistant professor at the Johns Hopkins Kimmel Cancer Center.

Borrello and his colleagues found that tumors exploit nitric oxide-producing immune cells to create a sort of “fog” that keeps them hidden from white blood cells (T-cells) that mount
'"/>




Page: 1 2

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
3. Nasal Spray Could Take Drugs Direct to Brain.
4. Emphasis to ban Drugs ads by Doctors
5. Osteoporosis Drugs: right time to take-off
6. Drugs disrupt formation of blood vessels
7. Drugs to stop burgeon of HIV
8. Misleading Advertisements for Prescription Drugs
9. Drugs For Anthrax May Interfere With Oral Contraceptives
10. Over-The-Counter Drugs May Prevent Alzheimers
11. Steps To Improve Quality Of Plant-Based Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Dysfunction Drugs Heighten Natural Anti Cancer Activiy

(Date:4/26/2015)... April 26, 2015 Forbes Living ... city is one which is synonymous with clean beaches, sparkling ... and education are major economic influencers in the city on ... dynamic talk show are pleased to announce the show will ... 26 at 3:00 PM PDT. Tune in to find out ...
(Date:4/26/2015)... Memphis, TN (PRWEB) April 26, 2015 ... plans to grow throughout the Southeast. MidSouth Pain Treatment ... clinic locations in Cordova, Southaven, Oxford and Jackson, two ... CLIA-certified laboratory in the Southaven and Cordova locations. , ... said ”I went into medicine to help people, ...
(Date:4/25/2015)... Portland, ME (PRWEB) April 26, 2015 ... a Canadian based integrative healthcare event. The Integrative ... taking place October 23-24, 2015 at the Sheraton ... Healthcare Symposium Canada is one of the most ... a clinically relevant, evidenced-based CME program. The event ...
(Date:4/25/2015)... In observance of World Malaria Day, today thousands ... a two-year pledge by the United Nations Foundation’s Nothing ... million bednets by 2016. This ambitious $10 million pledge ... protect children, refugees, and families displaced by conflict in ... a large surge in refugee families displaced by conflict ...
(Date:4/25/2015)... 2015 In the United States alone, ... needed treatment for an illicit drug or ... and Mental Health Services Administration’s Survey on Drug Use ... numbers are harrowing stories of men and women whose ... David H. Kerr , founder and retired president ...
Breaking Medicine News(10 mins):Health News:Forbes Living TV Will Air in San Diego, California 2Health News:Growing Pains for MidSouth Pain Treatment Center 2Health News:Integrative Healthcare Event launching in Canada 2Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 2Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 3Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 4Health News:New Book Features Powerful Stories of People Who Overcame Addiction 2Health News:New Book Features Powerful Stories of People Who Overcame Addiction 3
... guard this hospital, but I can,t afford to see ... at Kaiser Sunset Medical Center in Los Angeles OAKLAND, ... against unfair labor practices and slashed health benefits by ... Oakland and Los Angeles today. Workers chanted, marched, and ...
... Issued in Massachusetts General Hospital LawsuitVANCOUVER, May 21 /PRNewswire-FirstCall/ ... QLT) announced that on May 21, 2009, the District ... on QLT,s Motion to Dismiss all the claims filed ... General Hospital ("MGH") in its lawsuit against QLT. In ...
... Action to Improve Delivery of PMTCTGENEVA, May 21 ... in Geneva, members of the International Treatment Preparedness Coalition ... approximately 100 staff members of UNAIDS and WHO to ... Failing Women, Failing Children: HIV, Vertical Transmission and ...
... 21 As a health care practitioner, Trina Hammack ... with ovarian cancer, she knew her prognosis was bleak. ... Mexico offering effective new treatments for ovarian cancer. ... thousands of Americans diagnosed with cancer will travel to ...
... YORK, May 21 Immtech Pharmaceuticals, Inc. (OTC: IMMP) ... its common stock on the Pink OTC Markets quotation ... the ticker symbol "IMMP".As announced previously, on March 27, ... (the "Exchange") of its intention to initiate proceedings to ...
... MarketBERKELEY, Calif., May 21 In spite of fewer openings ... economic recession -- there is still a nursing shortage, according ... Institute for Nursing & Health Care (CINHC)."About half of all ... is just one factor in the job market for registered ...
Cached Medicine News:Health News:Security Officers Who Protect Kaiser Hospitals Rally With Community Supporters for Access to Affordable Healthcare 2Health News:QLT Announces Court Response to Motion to Dismiss and Removal of Case to Federal Court 2Health News:QLT Announces Court Response to Motion to Dismiss and Removal of Case to Federal Court 3Health News:AIDS Treatment Activists Push UNAIDS and WHO to Meet Commitments to Reduce HIV in Women and Newborns 2Health News:AIDS Treatment Activists Push UNAIDS and WHO to Meet Commitments to Reduce HIV in Women and Newborns 3Health News:The Diagnosis Every Woman Dreads - Ovarian Cancer 2Health News:The Diagnosis Every Woman Dreads - Ovarian Cancer 3Health News:Immtech to be Listed on OTC Market 2Health News:Hard Times for Nursing Hires Doesn't Signal End to Shortage According to California Institute for Nursing & Health Care 2
(Date:4/25/2015)... April 25, 2015  With the introduction of Elekta,s ... cranial radiosurgery are now available for more patients with ... latest generation stereotactic radiosurgery system for the brain, integrates ... increasing the versatility of Gamma Knife radiosurgery. Elekta unveiled ... ESTRO Forum in Barcelona . ...
(Date:4/24/2015)... 2015 Today, humanity takes a massive step toward ... fat-free cronuts: 1-800 CONTACTS announces their new Apple Watch app ... taps. Two taps. New contacts. From your watch. ... app also features LensGauge which helps keep track of how ... to reorder. "Since our inception, we,ve been dedicated ...
(Date:4/24/2015)... , April 24, 2015  Perrigo Company plc ("Perrigo" ... rejection of the unsolicited offer from Mylan NV ("Mylan") ... outstanding shares of Perrigo for $60.00 per share in ... Perrigo share (the "Offer").  The Board ... share significantly undervalued the Company and its future growth ...
Breaking Medicine Technology:New Leksell Gamma Knife to benefit more patients with brain disease 2New Leksell Gamma Knife to benefit more patients with brain disease 3Attention: We live in the future. Order contact lenses from your wrist with the 1-800 CONTACTS app for Apple Watch 2Perrigo Rejects Mylan Unsolicited Offer 2Perrigo Rejects Mylan Unsolicited Offer 3Perrigo Rejects Mylan Unsolicited Offer 4
... ZMH ; SIX: ZMH), a global leader in musculoskeletal care, ... Natural Nail Cephalomedullary Nail in the United States since ... Natural Nail system features an innovative design focused on restoring ... Nail Cephalomedullary Nail is designed to help address fractures of ...
... Mo., Oct. 13 The Keepsake exam at Prenatal ... the opportunity to evaluate fetal anatomy and environment, as ... fingers 10 toes, see their baby smile, frown and ... by a credential sonographer is the most important aspect ...
Cached Medicine Technology:Zimmer® Announces 1000th Implantation of Its Natural Nail™ Cephalomedullary Nail 2Zimmer® Announces 1000th Implantation of Its Natural Nail™ Cephalomedullary Nail 3Prenatal Imaging Centers, LLC Finds the 3D/4D Keepsake Exam an Opportunity to Screen Pregnancy 2
... Unparalleled Comfort Pick one of our pipettors ... the trigger and ejector positionsright where they should ... are ergonomically designed to help avoid repetitive stress ... Productivity In The Palm Of Your Hand ...
... for Unparalleled Comfort Pick one of our ... Notice the trigger and ejector positionsright where they ... pipettors are ergonomically designed to help avoid repetitive ... Productivity In The Palm Of Your Hand ...
... Ergonomic Design for Unparalleled Comfort Pick ... Notice the balance. Notice the trigger and ejector ... Thats because our pipettors are ergonomically designed to ... hours of pipetting. Productivity In The Palm ...
... The total ergonomic solution and best value ... feather touch action and ultra lightweight design ... tip ejection with long, lever tip ejector ... , Accepts universal tips or for greater ...
Medicine Products: