Navigation Links
Gene researchers make Malaria-resistant mosquito

A team of German and American researchers have used enetic engineering techniques to develop mosquitoes with a severely impaired ability to transmit malaria--at least to mice, new study findings show. The research is a "first step in the right direction" towards combating malaria in humans, study author Dr. Marcelo Jacobs-Lorena, of Case Western Reserve University in Ohio. "We now know it is possible to genetically modify mosquitoes to block the development of the (malaria) parasite. If the parasite cannot develop, it's not transmitted," Jacobs-Lorena explained.//

Malaria causes up to an estimated 1.5 million deaths per year. Vaccine development has so far proven unsuccessful since the malaria parasite lives in the bloodstream and therefore "evolves all the tricks to escape the body's immune defenses," Jacobs-Lorena said.

While pesticides have been used to kill the mosquitoes that carry malaria, the insects can develop resistance to pesticides. And the malaria parasites can become resistant to drugs used in humans, which requires the constant development of newer and consequently more expensive drugs.

As an alternative approach to combating malaria spread, Jacobs-Lorena and his colleagues attempted to genetically modify mosquitoes by introducing foreign genes into their germ line, or the genes that are passed on to future generations.

Once a mosquito consumes malaria-infected blood, the malaria parasite needs to cross over from the mosquito's gut into the blood in order to fully develop. In their research, published in the May 23rd issue of the journal Nature, Jacobs-Lorena and his team identified a snippet of protein called SM1 that attaches itself to the gut wall of the mosquito, essentially blocking the parasite.

The gene's activity is triggered when the mosquito feeds on blood, churning out SM1 "so when the parasite arrives, it doesn't find the right molecule," or any space to fit into, Jacobs-Lorena explain
'"/>




Page: 1 2

Related medicine news :

1. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
2. Calcium Supplementation May Not Actually Prevent colon cancer say researchers
3. Lung cancer molecular profile discovered by researchers.
4. A great hope for quitters of smoking by researchers
5. Vitamins may not protect against cancer say researchers
6. Autoimmune disorders studied in detail by U-M researchers.
7. A high BMI may not determine obesity, researchers say
8. Medical researchers being stifled by NHS Red tape
9. Dartmouth researchers zero-in on a gene that heightens muscle performance
10. Malaria-resistant Mosquito Developed
11. New initiative launched to fight malaria by repelling mosquitoes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene researchers make Malaria resistant mosquito

(Date:9/1/2014)... (HealthDay News) -- You may be able to convince your ... research suggests. The study included eight overweight and obese ... meant to change how people react to different foods. These ... and obese people who weren,t in the program. Both ... study and again six months later. The scans revealed that ...
(Date:9/1/2014)... September 01, 2014 Liver is the largest ... organ that helps the body in barring itself from poisons, ... of energy. Liver also plays many important functions such as ... glucose. , Many illnesses can affect the liver, an ... rib cage on the right side of the abdomen, reducing ...
(Date:9/1/2014)... 01, 2014 An operating theatre or ... for performing surgical operations. An operating room comprises a ... booms, operating room lights, imaging displays as well as ... by Transparency Market Research, a U.S.-based market research firm, ... USD 4.5 billion by 2019. , According to ...
(Date:9/1/2014)... 2014 "Women struggle with weight gain ... changes begin as early as 15, if not earlier. ... the ups and downs of hormone related weight gain. ... healthy sizes seems to rage against the hidden and ... in her 40's begin to face menopause and related ...
(Date:9/1/2014)... By Dennis Thompson ... -- An experimental Ebola drug previously given to two American ... the deadly virus in laboratory tests, researchers report. The ... it, even if they didn,t get the medication until five ... cases of Ebola who were days or even hours away ...
Breaking Medicine News(10 mins):Health News:Train Your Brain to Choose Fruit Salad Over French Fries 2Health News:Global Liver Diseases and Therapies Market- The Key Basics by Transparency Market Research 2Health News:Global Liver Diseases and Therapies Market- The Key Basics by Transparency Market Research 3Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 3Health News:Female Hormonal Imbalances - Can’t Seem to Shed Those Extra Pounds? Discussion with Medical Expert Dr. Clairborne on Dr. Carol Francis Talk Radio Today 2Health News:Female Hormonal Imbalances - Can’t Seem to Shed Those Extra Pounds? Discussion with Medical Expert Dr. Clairborne on Dr. Carol Francis Talk Radio Today 3Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 2Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 3
... - A recent study found no significant difference in the ... more than 30 days post-transient ischemic attack (TIA) or stroke ... post-event. Surgical literature recommends that the removal of ... of a TIA or stroke for the best outcomes. However, ...
... News) -- Sleep problems are associated with an increased risk ... older, a new study says. Fibromyalgia is a chronic ... in the United States. Women account for up to 90 ... age. Previous research has found that insomnia, nighttime awakening ...
... increasing evidence that repeated occupational exposure to certain ... Researchers analyzed the occupational histories of twins in ... disorder, and assessed that twin,s likelihood of exposure ... the six chemicals investigated, researchers concluded that two ...
... HealthDay Reporter , SUNDAY, Nov. 13 (HealthDay ... then exercised regularly for six weeks reported improved memory ... study. While the finding is encouraging, it does ... fibromyalgia patients, the study authors stressed. Senior author ...
... major international study has identified a novel gene mutation ... and sporadic cases of malignant melanoma, the most deadly ... in the gene encoding MITF, a transcription factor that ... the cells in which melanoma originates. While previous ...
... --,Girls who are severely physically and sexually abused may be ... as adults, according to a new study. Researchers ... among 67,100 women. Forced sexual activity during their childhood or ... and 9 percent reported severe physical abuse. , , Women ...
Cached Medicine News:Health News:Impact of timing on carotid artery stenting after stroke or transient ischemic attack 2Health News:Poor Sleep May Lead to Fibromyalgia in Women 2Health News:NIH-funded twin study finds occupational chemical exposure may be linked to Parkinson's risk 2Health News:NIH-funded twin study finds occupational chemical exposure may be linked to Parkinson's risk 3Health News:Study Suggests Exercise May Help Memory of Fibromyalgia Patients 2Health News:Study Suggests Exercise May Help Memory of Fibromyalgia Patients 3Health News:Newly identified gene mutation adds to melanoma risk 2Health News:Newly identified gene mutation adds to melanoma risk 3Health News:Abused Girls at Greater Risk for Heart Disease as Adults: Study 2
(Date:8/29/2014)... The clinical and medical insights provided by ... a product,s success or failure. Despite this, many biopharmaceutical ... – and then to coordinate activities and outreach over ... which successful KOL engagement rests. According ... inconsistencies in their KOL management systems and are working ...
(Date:8/29/2014)... WILSONVILLE, Ore. , Aug. 29, 2014 /PRNewswire-iReach/ ... its Accessory (Axilla) Strap for the SAM Junctional ... SAM Medical Products announced ... a voluntary recall to address a potential issue ... strap used for the Axilla application of the ...
(Date:8/29/2014)... , Aug. 29, 2014  A Boston Scientific ... study on stent removability and preliminary long term ... published in the August issue of the peer-reviewed ... 1 is being conducted in 11 countries ... covered self-expanding metal stents (FCSEMS) after extended indwell ...
Breaking Medicine Technology:Implementing a Strategic Thought Leader Management & Engagement System 2SAM Medical Products Implements Voluntary Recall of its Accessory (Axilla) Strap for the SAM Junctional Tourniquet. 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4
... Delcath Systems, Inc. (Nasdaq: ... its proprietary Percutaneous Hepatic Perfusion ("PHP(TM)") System for ... today that Dr. James F. Pingpank will present ... Therapies, to be held February 21-23, 2009. ...
... Mass., Feb. 18 ,Abbott ( NYSE: ABT ) ... Hepatitis C (HCV) collaboration with a first-in-human study,evaluating ... of chronic,HCV. The objectives of the trial ... was discovered as part of a worldwide alliance,between ...
Cached Medicine Technology:Dr. James F. Pingpank to Present at Leading Regional Therapies Conference 2Dr. James F. Pingpank to Present at Leading Regional Therapies Conference 3Dr. James F. Pingpank to Present at Leading Regional Therapies Conference 4Abbott and Enanta Initiate Phase 1 Clinical Trial on ABT-450 HCV Protease Inhibitor 2Abbott and Enanta Initiate Phase 1 Clinical Trial on ABT-450 HCV Protease Inhibitor 3
The LM-990A is the most completely automatic lensemeter ever created. It even measured monocular and binocular PD automatically....
... EyeSys Vista brings new freedom and ... the quality and excellence that are ... Vista offers eyecare practitioners a simple, ... topography that utilizes the same proven ...
... NEW Evolution electronic refractor to its line ... the convenience of a wireless, infrared remote ... automated refraction systems. The Evolution gives the ... through the handheld remote control. With the ...
Uniquely designed, the wheelchair table has dual purposes. Not only does it add a modern look to any office, it is also a heavy-duty table that will support multiple instruments, and/or easily accomm...
Medicine Products: