Navigation Links
New Technique To Test Stem Cells That Heal The Heart

Researchers from the Johns Hopkins Department of had discovered a new way to test the stem cells journey in the heart after a heart attack. //

The researchers had used a non-invasive imaging technique, called SPECT/CT, to successfully trace stem cells’ destinations after being injected into the body to treat animal hearts damaged by myocardial infarction, or heart attack.

In the study, researchers surgically induced acute myocardial infarctions in seven dogs, six of which later received canine mesenchymal stem cells (MSCs) labeled with a radioactive tracer and magnetic resonance imaging (MRI) contrast agent to enhance image quality. Both the tracer and contrast agent are widely used in research and routine clinical practice.

The internal distribution of the injected stem cells was tracked with SPECT/CT and MRI scanners immediately after injection as well as at multiple time points over seven days to assess whether the MSCs preferentially migrated or “homed” in on damaged cardiac tissue. Previous studies in animals were only able to demonstrate homing by examining the tissue microscopically after death.

The team’s results, reported in the latest issue of Circulation, revealed redistribution of the radio-labeled MSCs from the initial localization in the lungs to the target organ, the heart, at 24 hours post-injection. Moreover, the cells remained visible in SPECT/CT images until seven days after the injection.

SPECT/CT also found redistribution of the MSCs to non-target organs, such as the liver, kidney and spleen. Measuring the radiation levels in tissues obtained from the animals after their death validated these findings.

MRI, because of its lower sensitivity, was unable to demonstrate targeted cardiac localization of MSCs.

Page: 1

Related medicine news :

1. New Laser Techniques cure degeneration of the eye
2. New Technique to Study Infants Brain.
3. New Technique For Benign Breast Tumors
4. Preventing Strokes Using Less Invasive Techniques
5. New Technique To Detect Activity Of Drugs In The Body
6. A New Technique For Prediction Of Adult Height
7. Novel Technique For Targeting Small-Cell Lung Cancer
8. Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus
9. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins
10. New Technique Enables Better Nursing Of Robin Sequence Infants
11. Novel Technique Can Enhance Stem Cell Multiplication By 30 Fold
Post Your Comments:

(Date:11/24/2015)... ... November 24, 2015 , ... Cancer patients, ... and experiences at a live taping of the next CURE Connections® ... of Gastrointestinal Cancers 2015 Symposium at Georgetown University Hotel & Conference Center in ...
(Date:11/24/2015)... ... 2015 , ... With Thanksgiving right around the corner, holiday travel season is ... your family and vehicle. , According to the National Highway Traffic Safety Administration, 301 ... sharing the following safety tips from the NHTSA: , ...
(Date:11/24/2015)... ... November 24, 2015 , ... Chiropractic student Katie Benson received ... in Overland Park, Kansas. Benson, a fifth-trimester student in the university’s College of ... on October 16. , “Katie is very excited and greatly appreciative to receive ...
(Date:11/24/2015)... ... November 24, 2015 , ... Bibliomotion is thrilled to announce ... about Reinvention and Diversity by Nancy M. Schlichting, Chief Executive Officer of ... to adequately address the needs of patients and their families, shaped my desire to ...
(Date:11/24/2015)... ... ... All her life, Don Peck’s mother wondered if she was a descendant of Samuel Fuller, ... After a 25-year search for information, Don and his aunt discovered that she was not, ... Turns out, it was Don’s father who was descended from not one, but four passengers ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... PUNE, India , November 24, 2015 ... new market research report "Spine Biologics Market by Product Type ... Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), ... by MarketsandMarkets, the global market was valued at $1.90 Billion ... 2020, at a CAGR of 4.4% during the forecast period ...
(Date:11/24/2015)... , Nov. 24, 2015 Avery Biomedical Devices ... pleased to announce the appointment of Anders Jonzon ... Dr. Jonzon is ... at Children,s Hospital, Uppsala University, Uppsala and Children,s Hospital, ... he was a fellow at the Cardiovascular Institute (UCSF). ...
(Date:11/24/2015)... 24, 2015 . ... adds Latest Guidebook for Chinese Medical Device ... published in November 2015 to the medical devices ... library at . ... growing global economies with a fifth population in ...
Breaking Medicine Technology: