Navigation Links
"Umbrella" Valve Provides Potential Alternative to Lung Surgery

A new umbrella-like valve may help patients with emphysema breathe easier and may ultimately provide a noninvasive alternative to lung reduction surgery. // In a new study presented at CHEST 2006, the 72nd annual international scientific assembly of the American College of Chest Physicians (ACCP), the IBV? Valve, a nonsurgical, investigational device, was shown to be safe and effective for patients with emphysema.

Emphysema — a subtype of chronic obstructive pulmonary disease (COPD) — is a progressive and debilitating lung disorder, characterized by irreversible airflow obstruction. Current management for emphysema includes medication and/or supplemental oxygen, pulmonary rehabilitation, and, in rare cases, lung volume reduction surgery (LVRS) to remove the most diseased portions of the lung.

“The IBV? Valve is similar in concept to LVRS in that it aims to make the lungs work more efficiently, thereby decreasing shortness of breath,” said the study’s lead author Daniel H. Sterman, MD, FCCP, University of Pennsylvania Medical Center, Philadelphia, PA. “Unlike lung reduction surgery, valve treatment has fewer complications and a shorter hospital stay. For example, most valve-treated patients have a one-night observational hospital stay while surgical patients average a week or more in the hospital.” The one-way IBV? Valve limits ventilation in diseased areas of the lungs and redirects ventilation to the remaining healthier portions of the lung while allowing for normal clearance of secretions.

In a multicenter preliminary pilot study, Dr. Sterman and researchers from the Cleveland Clinic Foundation, Cleveland, OH, University of Washington, Seattle, WA, and six additional US medical centers examined the safety and effectiveness of the IBV? Valve on patients with severe upper-lobe emphysema. Over a 27-month period, 520 valves were implanted in 75 patients across the nine medical centers. The valves were implanted in the upper lobes o f the lung using flexible bronchoscopy, with an average of 6 to 7 valves implanted per patient. Researchers used quantitative software and multidetector CT scans to measure the physical effects of the valves and the St. George Respiratory Questionnaire (SGRQ) to assess how patients felt after treatment.

Of the patients who received valve treatment, 46 patients (group A) had reduced complications and retained efficacy compared with the remaining patients (group B). In responding patients, valve treatment transferred an average of 20 percent ventilation and perfusion to healthier regions of the lung. Two thirds of patients in group A also had a 4-point or more SGRQ improvement at 6 months and showed significant improvements in oxygen use and DLCO. Compared with patients in group B, patients in group A were less than 75 years old, did not have lingular treatment, and had fewer lung segments treated. The 90-day serious complications were one bronchospasm and one COPD flare in the A group and two bronchospasm and one death with pneumothorax in group B.

“Patients responding to valve treatment may now be able to do simple, everyday activities, such as bathe or shower independently, walk around the house without stopping, talk without trouble breathing, and can go out for shopping or entertainment,” said study coauthor Atul C. Mehta, MD, FCCP, Cleveland Clinic Foundation. “Although valve treatment is still investigational, it may offer an alternative treatment for patients with emphysema who are not good candidates for LVRS.” Researchers stress that valve treatment is not yet approved by the US Food and Drug Administration and is only available as part of a research trial that is currently sponsored by the developer of the IBV? Valve, Spiration, Inc.

“Although there is no cure for emphysema, proper treatment can improve a patient’s exercise capacity, overall quality of life, and may result in longer survival,” said Mark J. Rosen, MD, FC CP, President of the American College of Chest Physicians. “Valve treatment may represent a valuable option for the palliative treatment of patients with emphysema.”

Source-ewswise
SRM
'"/>




Related medicine news :

1. Cardiac Valve Disease Linked To Genes
2. ResQ-Valve With CPR In Cardiac Arrest Patients To Be Assessed By National Study
3. Valve Disease Study Suggests New Public Health Concern
4. First Keyhole Heart Valve Surgery Scheduled in Britain
5. Drug Spironolactone Provides Renal And Cardioprotection In Diabetic Patients
6. Neurobiology Provides Answers To Block Memory-Related Drug Cravings
7. London Hospital Provides Specialized Care For Pregnant Women
8. Breastfeeding Provides Added Protection To Babies
9. Far East Provides A Path To Contain Bird Flu
10. Direct To Home: Television Provides Powerful Fillip to Smoking Cessation Campaigns.
11. Latest Version of Echocardiography Provides Improved Pictures of the Heart
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... Maryland (PRWEB) , ... October 12, 2017 , ... ... magnetic drug delivery system that we intend to develop to enable prevention of ... can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... FL (PRWEB) , ... October 12, 2017 , ... On ... holding a treadmill relay – Miles by Moonlight to raise money for the American ... $300 or more. , Teams will work together to keep their treadmills moving ...
(Date:10/12/2017)... ... 12, 2017 , ... Health Literacy Innovations (HLI), creator of ... and the Cancer Patient Education Network (CPEN), an independent professional organization that shares ... strategic alliance. , As CPEN’s strategic partner, HLI will help support CPEN ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
(Date:9/19/2017)... --  ZirMed Inc ., a recognized leader in cloud-based revenue ... been ranked #1 by its users for the seventh consecutive ... Survey. ZirMed was recognized as the top-ranked end-to-end revenue cycle ... over 200 beds and holds one of the longest #1 ... ...
(Date:9/12/2017)... Sept. 12, 2017  Consumer reviews on the independent review site ... the number one company for hearing aids, ranking it higher than ... brands. ... #1 by Consumers For Hearing Aids ... Hearing is an online store that provides high performance, state-of-the-art, German-engineered ...
Breaking Medicine Technology: