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"Beach to Bedside" Study Focuses on Effects of Inhaled Toxins

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This study is one of the most far-reaching and inclusive in the history of red tide research. Working together across disciplines, oceanographers, chemists, toxicologists, public health specialists, physicians and biomedical scientists approach the problem in a "beach to bedside" manner, emulating the "bench to bedside" mantra of current National Institutes of Health-funded research that leads to clinical intervention. By measuring red tide cells in the water, the toxin they contain, the airborne toxin in sea spray, the toxin transported ashore by wind and the amount people inhale, the team is rapidly increasing understanding about one of the most far-reaching human exposures to a natural toxin.

Florida red tide toxins affect the pulmonary, nervous, immune and genetic systems in animal models and may similarly affect humans. The study, beginning its sixth year, has presented its findings to the Society of Toxicology, to the International Society on Exposure Analysis, to the CDC and Florida DOH and to scientific and lay audiences alike. More than 80 published articles detail findings to date, and three patents dealing with seafood poisoning and pulmonary therapeutics have resulted from the work.

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