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Tests showing smokers their individual risk of future disease will help them quit, says paper
Date:2/4/2010

ular risk assessment and treatment.

According to studies cited in the article, genetic testing for smoking-related disease demonstrated utility for all smokers and found no evidence of fatalism in higher risk people or reduced motivation for those at lower risk levels.

Smokers' attitudes about whether to carry on smoking are based on how they balance the perceived "benefits" against their understanding about the harm it causes, and their individual vulnerability to this harm, according to studies cited in the PMJ article. The "Editor's Choice" paper says even relatively small triggers can change this balance, prompting a quit attempt.

Currently, the smoking quit rate remains discouragingly low. Smokers try to quit on average 12 to 14 times before they succeed, and only about 5% of cold-turkey tries work. Every year about 41% of smokers try to quit but only 10% succeed. Drugs and nicotine replacement help, but still achieve one-year quit rates of only up to 30%.

The paper says recent research shows says smoking cessation 'interventions' by doctors that give both a trigger for action and also provide support such as medication or anti-smoking counselling may be the most effective way to help smokers quit.

A similar approach works for coronary artery disease, where cholesterol testing to personalise an individual's risk helps give doctors a way to encourage patients to make lifestyle changes or take medications. "The recent reduction in coronary artery disease mortality has, in part, been attributed to this approach," the paper says.

For smokers, both spirometry and genetic testing appear to improve quit rates, it says.

Dr Young, an Associate Professor in the Schools of Biological Sciences and Medicine at the University of Auckland in New Zealand, has led the research program underpinning a test called Respiragene which combines genetic and non-genetic factors to show smokers and ex-smokers their ow
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Contact: Ken Li
media@respiragene.com
312-532-4675
Chempetitive Group
Source:Eurekalert

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