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Scientists crack medieval bone code
Date:1/3/2012

ntury to the 13th century had significant lesions, leading the researchers to theorize the boys had suffered from tuberculosis.

Samples of the ancient bone were sent to the forensic DNA lab in East Lansing, which is headed by David Foran, director of MSU's Forensic Science Program. Foran and his team of graduate students took tiny portions of the bone, extracted DNA and tested it for any residual DNA that might still exist from the expected pathogen.

But the results came back negative for tuberculosis.

Fenton's team re-examined the bones that tested negative for tuberculosis and concluded the disease might instead be brucellosis. The infection from brucellosis and tuberculosis causes similar damage basically eating away the bone although no one had ever confirmed brucellosis in human bone recovered from an archaeological site.

Foran's team then developed a different set of tests for detecting the brucella bacteria and undertook a new round of testing on the diseased vertebrae.

This time the results came back positive for brucellosis.

Foran said the collaboration on the project highlights the benefits of modern science and interdisciplinary research, even when the respective research teams are some 5,000 miles apart.

"In this case it was a combination of inquisitiveness, persistence and of course collaboration," Foran said. "It is amazing to find something brand new in something that is a thousand years old."


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Contact: David Foran
foran@msu.edu
517-432-5439
Michigan State University
Source:Eurekalert  

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