Navigation Links
Researchers discover link between obesity gene and breast cancer
Date:5/23/2011

New research aimed to better identify the genetic factors that lead to breast cancer has uncovered a link between the fat mass and obesity associated gene (FTO) and a higher incidence of breast cancer. According to the study conducted at Northwestern Memorial Hospital, people who possess a variant of the FTO gene have up to a 30 percent greater chance of developing breast cancer. Research to identify why the link exists is ongoing, but experts say the finding takes us one step closer to personalized medicine based on genetic risk which would allow for better monitoring and prevention of illness, as well as targeted treatment.

"This is a fascinating early finding, which fits with the known connections between obesity and breast cancer," said Virginia Kaklamani, MD, oncologist at Northwestern Memorial, co-director of the Cancer Genetics Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and lead author of the study.

Each individual carries the FTO gene, but only 18 percent have this variant of the gene. Kaklamani, who specializes in cancer genetics, says testing for the FTO variant is not available currently, but it may be available in the future, similar to how genetic testing for the BRCA gene mutation exists today.

"Ten years ago we didn't know about the BRCA gene mutation which has been linked to breast and ovarian cancer. Today, we offer genetic testing and a specialized clinic for those at risk in order to minimize their risk and detect any indication of cancer early," said Kaklamani, who is also an associate professor of medicine at Northwestern University Feinberg School of Medicine. "This knowledge helps us better identify who is at an increased risk so one day, we can counter that risk through preventative measures and advanced screening."

The research, published in BMC Medical Genetics is part of an ongoing group of studies to further knowledge of genetic ris
'/>"/>

Contact: Angela Salerno
asalerno@nmh.org
312-926-8327
Northwestern Memorial Hospital
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2013)... published an original art book for iPad with tango as ... who share their creations based on the traditional music genre ... iPad . , This work gathers more than 150 ... signature idiosyncrasy and passion of tango. Such book is ... it includes a free trailer of the book for readers ...
(Date:5/18/2013)... There are significant cost and risk factors ... or treat gastrointestinal problems, according to research presented ... study by New York Presbyterian Hospital and Weill-Cornell ... substantially reduce the cost and risk of managing ... to affect nearly 25 percent of adults, researchers ...
(Date:5/18/2013)... In a May 14, 2013 article entitled ... Discovering Cancer Gene,” Fox News reported the movie star ... she carried a gene that doctors estimated gave her ... 50 percent risk of ovarian cancer (go to: goo.gl/5JHBP). ... 2013 with a blog post entitled “A Patient’s Journey: ...
(Date:5/18/2013)... Orlando, FL (May 18, 2013) A ground-breaking ... colorectal care, according to research presented today at ... optimizing the minimal withdrawal time for colonoscopies and ... , During colonoscopy, doctors use a device called ... test for colorectal cancer allows a doctor to ...
(Date:5/18/2013)... York (PRWEB) May 18, 2013 ... mesh products continue to move forward in a consolidated ... Bernstein Liebhard LLP reports. According to a notice on ... the Ethicon pelvic mesh litigation will be held on ... complaints have been filed in the proceeding on behalf ...
Breaking Medicine News(10 mins):Health News:New Art Book for iPad: Tango Art 2Health News:New research identifies practice changes to improve value and quality of GI procedures 2Health News:Angelina Jolie – Scarless Breast Augmentation Surgery 2Health News:New colonoscope provides ground-breaking view of colon 2Health News:New colonoscope provides ground-breaking view of colon 3Health News:New colonoscope provides ground-breaking view of colon 4Health News:Transvaginal Mesh Lawsuits: Bernstein Liebhard LLP Notes Upcoming Case Management Conference in New Jersey Ethicon Pelvic Mesh Litigation 2Health News:Transvaginal Mesh Lawsuits: Bernstein Liebhard LLP Notes Upcoming Case Management Conference in New Jersey Ethicon Pelvic Mesh Litigation 3
... 29 Increasing literacy and,curbing HIV/AIDS is the centerpiece ... effort designed to stabilize parts of,Haiti plagued by community ... $19 million investment -- will,target public and private primary ... to Rebecca Adams, who manages a worldwide education and,health ...
... 29 Medial Saude S/A,(BOVESPA: MEDI3) (MEDIAL SAUDE) announces the following webcast:, ... Conference Call, When: Thursday, August 7, 2008 @ ... http://prnewswire.isat.com.br/?palestra_id=380 ... Internet -- Simply log on to the web at the ...
... WHITE PLAINS, NY Babies born too soon and too ... to new statistics released today from the National Center for ... causes accounted for 36.5 percent of infant deaths in 2005, ... Statistics from the 2005 Period Linked Birth/Infant Death Data Set," ...
... 29 Many parents may not realize that,their preteens ... a serious,disease that spreads easily. Whooping cough can cause ... more, and may lead to vomiting, pneumonia and,missed school ... http://media.medialink.com/WebNR.aspx?story=35397 , Registered journalists can access video, audio, ...
... picket outside Sutter Medical Center of Santa Rosa, ... issued by SEIU United Healthcare Workers - West:, ... to demonstrate their alarm at a growing healthcare crisis ... Sutter hospital workers next,month. The announced elimination of 120 ...
... international standards to ensure safety, reliable results , , TUESDAY, ... a common part of cancer care and research, but ... guidelines, say Duke University Medical Center researchers. , In ... pre-surgical fitness of lung cancer patients. In cancer research, ...
Cached Medicine News:Health News:Three Rs and HIV/AIDS Mark New Haiti Literacy Plan 2Health News:Preterm birth contributes to growing number of infant deaths 2Health News:Workers Denounce Sutter Health's Disregard for Community Interests 2Health News:Exercise Testing for Cancer Fails to Follow Guidelines 2
(Date:5/17/2013)... May 17, 2013 Research ... and outcomes research also   to   be presented ... SHPG ), the global specialty biopharmaceutical company, announces ... presentations at the American Psychiatric Association (APA) 166th Annual ... 18-22. The data being presented represent Shire,s ongoing commitment ...
(Date:5/17/2013)... LAKES, Fla. , May 17, 2013 Fuse ... and delivery technology company that is developing new, patent-pending technologies ... minerals, announced today that it will hold a business update ... Wednesday, May 22 nd , 2013 at 4:30 PM ET. ... Tuffin will host the call and will be ...
(Date:5/17/2013)... 2013 Oramed Pharmaceuticals Inc. (NASDAQCM: ... delivery systems, announced today that the United States Food ... New Drug application(IND) for ORMD-0801, its oral insulin capsule. ... FDA clearance to proceed," stated Nadav Kidron ... a major milestone for Oramed and we look forward ...
Breaking Medicine Technology:Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 2Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 3Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 4Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 5Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 6Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 7Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 8Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 9Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 10Fuse Science, Inc. to Hold Business Update Webcast and Teleconference on May 22nd 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 3
Nidek offers 3-Dx Digital stereo camera to provide a complete and comprehensive digital imaging platform....
Measurement of progressive multi-focal lenses is fast and easy with the CLM-3000 auto-lensmeter. The data is represented in a simple to understand bar graphic display....
Auto Lensmeter LM-970...
Autolensmeter with black/white monitor and no internal printer....
Medicine Products: