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Novel immunotherapy drug receives FDA approval for the treatment of metastatic melanoma
Date:3/25/2011
patients as we now build on the success of ipilimumab with novel combination therapies."
"The success of ipilimumab underscores the importance of basic research to clinical achievement," Dr. Allison added. "The concept came directly out of our studies on fundamental mechanisms of regulation of T cell responses."
In addition, researchers at the Center are studying biomarkers to help identify those patients who could benefit most from therapies like ipilimumab, and they have received a National Institutes of Health Grand Opportunity Stimulus award to study how the immune response to the NY-ESO-1 antigen is related to clinical outcome for ipilimumab therapy. This work, which is being conducted in several large clinical trials, is also supported by grants from the Melanoma Research Alliance and the Cancer Research Institute.
According to the National Cancer Institute, 68,130 new cases of melanoma were diagnosed in the United States in 2010, and 8,700 Americans died from the disease. Melanoma is the least common form of skin cancer, but is considered the most serious.
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| Contact: Jeanne DAgostino dagostij@mskcc.org 212-639-3573 Memorial Sloan-Kettering Cancer Center Source:Eurekalert |
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