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New therapies and gene target advance the treatment and understanding of hard-to-treat leukemias
Date:12/6/2010

(ORLANDO, December 4, 2010) Over the past decade, significant advances have been made in the treatment of leukemia through the ongoing development of gene-based targeted therapies. Research that will be presented today at the 52nd Annual Meeting of the American Society of Hematology provides greater understanding of the optimal use of several BCR-ABL inhibitors for the treatment of acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML), and how a new gene target functions for several myeloid malignancies.

"Each year, we continue to make significant strides in better understanding the underlying role certain genes play in the development of various forms of leukemia," said moderator of the press conference Peter Emanuel, MD, Director of the Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock. "These studies underscore the advances we are making to develop a new generation of treatment options that will improve overall outcomes for our patients."

This press conference will take place on Saturday, December 4, at 2:00 p.m.

Imatinib Significantly Enhances Long-Term Outcomes in Philadelphia Positive Acute Lymphoblastic Leukemia; Final Results of the UKALLXII/ECOG2993 Trial [Abstract 169]

Acute lymphoblastic leukemia (ALL), a cancer of the white blood cells, is the most common type of leukemia, with about 3,930 new cases diagnosed each year in the United States.1 According to researchers, approximately 20 to 25 percent of all adults with ALL have a genetic abnormality in which some genetic material from chromosome 9 switches position with some genetic material from chromosome 22. This condition is known as Philadelphia chromosome-positive (Ph+) ALL, which is a rapidly progressive form of leukemia. It is associated with a poor prognosis since
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Contact: Lindsey Love
llove@hematology.org
540-538-9326
American Society of Hematology
Source:Eurekalert

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