Navigation Links
New Drug May Relieve Severe, Tough-to-Treat Gout
Date:8/16/2011

grams of pegloticase bi-weekly; a second to receive the drug once a month; and the third placed on injectable saline (a placebo).

The result: all patients receiving pegloticase experienced a rapid drop in their uric acid levels to ranges considered normal. However, in some cases the uric acid decline was temporary, the investigators found.

The study indicated that the new treatment will not help all of the estimated 120,000 to 180,000 Americans with this most severe type of gout. In fact, the medication appeared to elicit an all-or-nothing response, greatly helping some patients while having almost no effect on others.

Ultimately, the research team found that 42 percent of the bi-weekly pegloticase patients maintained normal uric acid levels for a minimum of 80 percent of the half-year study period. The same was true among 35 percent of the monthly pegloticase patients. Those given saline solutions saw no improvement at all.

Overall, the quality of life went up among both sets of pegloticase patients, as did mobility and function; there was also a reduction in pain. What's more, many of the lumps typically associated with long-term gout (called "tophi") resolved in roughly 40 percent and 20 percent of the bi-weekly and monthly pegloticase patients, respectively.

However, the authors said 90 percent of pegloticase patients experienced at least one side effect, most commonly a brief flare-up of gout. Such flare-up side effects are also a common feature among allopurinol patients in the immediate period following treatment launch.

More seriously, about one-quarter of the bi-weekly pegloticase patients and 42 percent who had monthly injections experienced infusion-related immune responses at the drug injection site. In 5 percent to 8 percent of patients, the reaction was serious, and five patients experienced anaphylaxis.

Dr. Tuhina Neogi, an associate professor of medicine at Boston University School of Medicine, said: "The va
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Hypnosis can relieve symptoms in children with respiratory diseases
2. Acupuncture may relieve joint pain caused by some breast cancer treatments
3. Hormone Replacement Might Relieve Arthritis
4. Botox Injections May Relieve Tennis Elbow Pain
5. Non-medical treatment may rapidly relieve severe IBS symptoms
6. Nonmedical treatment may rapidly relieve severe IBS symptoms
7. Local Anesthetic May Relieve PTSD Symptoms
8. Talking to Mom by Phone May Relieve a Daughters Stress
9. Self-directed behavioral IBS treatment rapidly relieves even the most severe symptoms
10. Choir Singing May Relieve Irritable Bowel Syndrome
11. New drugs to relieve cancer pain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Drug May Relieve Severe, Tough-to-Treat Gout
(Date:5/25/2013)... Actos lawsuit claims pending ... Court, Western District of Louisiana, continue to move forward, ... Management Order issued on May 21st, the Court has ... in the Actos bladder cancer litigation, as well as ... Liability Litigation, MDL No. 2299) , “We continue to ...
(Date:5/25/2013)... 2013 Radius Engineering International Inc., ... in the US and has been building concrete, ... 35 years. M.E. and President, Walton McCarthy, author ... Weapon Fundamentals and Shelter Engineering Standards, Sixth Edition, ... shelter engineering. McCarthy is considered the leading expert ...
(Date:5/25/2013)... NY (PRWEB) May 25, 2013 On May ... many people do not wish to discuss or plan for ... life. FuneralFinancials.com released a Must-Do List to ... 1. Funeral Financials recommends, “Creating a personal fact sheet.” , ... to organize financial information and personal data. It may ...
(Date:5/25/2013)... New York, NY (PRWEB) May 25, 2013 ... organization dedicated to brain cancer research and advocacy, comments ... for Extraterrestrial Physics, that shows incorporating cold atmospheric plasma ... glioblastoma cells. , According to a Science ... for Extraterrestrial Physics (MPE), biologists and physicians demonstrated the ...
(Date:5/25/2013)... According to world-renowned scholars, Queen Cleopatra VII was ... ever lived. Cleopatra’s legendary beauty moved nations and her ... men in her time. Cleopatra was also a scientist ... glowing and fresh, from her legendary milk baths to ... cyprus grass. , Cleopatra was said to possess the ...
Breaking Medicine News(10 mins):Health News:Actos Lawsuit News: Bernstein Liebhard LLP Notes New Case Management Order in Federal Actos Bladder Cancer Litigation 2Health News:Actos Lawsuit News: Bernstein Liebhard LLP Notes New Case Management Order in Federal Actos Bladder Cancer Litigation 3Health News:Radius Engineering International Inc. Offers Tools to Stay Safe and Recover From Any Disaster 2Health News:Radius Engineering International Inc. Offers Tools to Stay Safe and Recover From Any Disaster 3Health News:FuneralFinancials.com Releases Last Wishes Must-Do List 2Health News:Voices Against Brain Cancer Comments on Study that Shows Cold Plasma’s Success Against Brain Cancer Cells 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 3
... Caregivers say it,s time for Sal Rosselli and others to admit they ... , , Ousted officials have now been rejected ... Sept. 15 Home care workers demanded today that an organization created by ... new union election. The San Francisco workers say they overwhelmingly want to stay ...
... School of Medicine scientists have received more than ... economic stimulus legislation, funding that has bolstered both ... center campus. More than 40 researchers have ... from a $1.4 million National Science Foundation grant ...
... BETHPAGE, N.Y., Sept. 15 The Lustgarten Foundation, the nation,s ... of pancreatic cancer, today issued the following statement on the ... , Kerri Kaplan, Lustgarten Foundation Executive Director, said: ... His courageous, public battle with pancreatic cancer serves as an ...
... , PHILADELPHIA, Sept. 15 Come rejuvenate your ... Saturday, September 19, 11 a.m. to 4 p.m., at the Pennsylvania ... The Wellness of You, Inc., and Universal Companies , ... presentation of the Tree of Life Award to nationally ...
... , , , DULUTH, Ga., ... chemicals that act as endocrine disruptors, which hinder the normal functions ... added to plastics to make them flexible to mold into shapes ... Parabens are added to personal care products, such as cosmetics, to ...
... HOUSTON, Sept. 15 A research project looking for ways ... the bone health of cancer patients undergoing radiation treatment. , ... microgravity environment of space causes bone loss in astronauts, but until ... bones. Dr. Ted Bateman leads a project funded by the ...
Cached Medicine News:Health News:San Francisco Home Care Workers Demand that Former Union Officials Come Clean 2Health News:San Francisco Home Care Workers Demand that Former Union Officials Come Clean 3Health News:Indiana U medical researchers boost research and jobs with stimulus legislation grants 2Health News:Indiana U medical researchers boost research and jobs with stimulus legislation grants 3Health News:Indiana U medical researchers boost research and jobs with stimulus legislation grants 4Health News:The Lustgarten Foundation Says Patrick Swayze's Death Highlights the Need for Increased Research into Early Diagnosis and Treatment of Pancreatic Cancer 2Health News:The Celebrate Wellness Expo Presents Motivational Speaker & Author Dr. Robin L. Smith and Spiritual Teacher & Author Rev. Michael Bernard Beckwith 2Health News:Metametrix Announces Availability of Phthalates & Parabens Profile to Help Identify Everyday Exposures 2Health News:Metametrix Announces Availability of Phthalates & Parabens Profile to Help Identify Everyday Exposures 3Health News:Space-Related Radiation Research Could Help Reduce Fractures in Cancer Survivors 2Health News:Space-Related Radiation Research Could Help Reduce Fractures in Cancer Survivors 3Health News:Space-Related Radiation Research Could Help Reduce Fractures in Cancer Survivors 4
(Date:5/23/2013)... y PARÍS, 24 de mayo de 2013 /PRNewswire/ ... destacado desarrollador y fabricante de herramientas de precisión ... y tratamiento de la enfermedad vascular periférica y ... ADVISE ( Ad enosine V asodilator ... II durante la sesión de ensayo clínico hot ...
(Date:5/23/2013)... health affects a man,s lifestyle, and if he wants to ... he should address any hearing loss he may be experiencing. ... Institute (BHI) is delivering to men around the country ... leads up to and includes Father,s Day. This year, National ... To help men address their hearing health ...
(Date:5/23/2013)... May 23, 2013 More than half of ... benefit from chemotherapy and still have excellent outcomes. To ... one of the largest sources of online consumer information ... interactive Facebook page provide recently diagnosed women with information ... avoid chemotherapy. "We anticipate these innovative social ...
Breaking Medicine Technology:Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3
... Five years after the identification of,the gene responsible ... ageing, a team of Spanish and French researchers ... and Nicolas Levy and coll. -,Inserm/AP-HM, Marseille, France) ... mice. This treatment, combining two existing,pharmacological molecules, should ...
... At its annual R&D,event being held today ... ) will,provide an update on progress in all ... marketing rollout for its growing range of,DNA-based diagnostic ... recent progress in its drug development,programs; and how ...
Cached Medicine Technology:Hope for Progeria - Successfully Validated on Mice, a Treatment Could Soon be Tested on Children 2Marketing of Diagnostics and deCODEme(TM), Recent Progress in Drug Development to be Highlighted at deCODE R&D Event 2Marketing of Diagnostics and deCODEme(TM), Recent Progress in Drug Development to be Highlighted at deCODE R&D Event 3
An easy-to-fit high water content spherical soft lens manufactured using cast molding technology, and designed for use in the correction of myopia on a daily wear or extended wear basis....
Hertel exophthalmometer...
1-Day Acuvue brand contact lenses offer the healthiest, most convenient way to wear contact lenses. There's no lens care or messy solutions required, just wear them one day and throw them away....
... connects via a USB port ... computer featuring Windows 2000 or ... the art corneal topography software ... projection and easy alignment reduce ...
Medicine Products: