Navigation Links
mTOR Signaling and Depression Published by Dove Medical Press
Date:12/8/2015

The Journal of Receptor, Ligand and Channel Research has published the review “mTOR signaling in the neuropathophysiology of depression: current evidence”.

As corresponding author Dr Ana Lúcia Rodrigues says “The review by Reus et al deals with the role of mammalian target of rapamycin (mTOR) signaling in the neuropathophysiology of depression. A special focus is given to ketamine, a fast-acting antidepressant that elicits its antidepressant effect by activating this pathway in prefrontal cortex and hippocampus. This forms the basis for the review which evaluates mTOR as a neurobiological feature of depression and as a target for antidepressant treatment.”

Dr Rodrigues continues “It is concluded that a better understanding on the role of mTOR signaling in different brain regions and its upstream and downstream targets may provide novel insights into the development of therapeutic approaches for the management of depression.”

As Professor Trevor W. Stone, Editor-in-Chief, explains “The search for effective but safe anti-depressant drugs continues in parallel with studies of dietary influences and the use of lifestyle factors such as exercise. In this short review Rodrigues and colleagues summarise key findings on these topics and draw together the evidence that they may act via a common pathway known as mTOR (mammalian Target Of Rapamycin). A more intensive investigation into this target could yield the more selective and useful drugs that are urgently needed.”

The Journal of Receptor, Ligand and Channel Research is an international, peer-reviewed, open access, online journal. The journal welcomes laboratory and clinical findings in the fields of biological receptors, ligands, channel and signal transduction research.

Dove Medical Press Ltd is a privately held company specializing in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine.

Read the full story at http://www.prweb.com/releases/2015/12/prweb13118848.htm.


'/>"/>
Source: PRWeb
Copyright©2015 Vocus, Inc.
All rights reserved


Related medicine news :

1. MAD: Scientists shed light on braking mechanisms in cellular signaling
2. Signaling pathway may explain the body clocks link to mental illness
3. Cell signaling pathway linked to obesity, type 2 diabetes
4. Artesyn Embedded Technologies Launches New COTS Fail-Safe System Designed to be Certified to SIL4 for Train Control and Rail Signaling
5. Dialogic’s Next Generation Diameter Signaling Controller Helps DOCOMO PACIFIC Implement 4G Roaming
6. Dialogic’s Integrated Signaling Controller Helps IT&E Replace Its SS7 Network and Prepare for 4G Roaming
7. Advera Health Analytics Launches RxSignal® 3.0, the Only Post-Marketing Signaling System to Predict FDA Action on Label Changes
8. Cell Signaling Technology Webinar Underscores Importance of AMPK in studies for Cancer and Diabetes
9. Diet Doc Hormone Diets & Weight Loss Plans Announce New Hormone Diets to Help New Mothers Lose Weight and Avoid Post Pregnancy Depression
10. Studies pinpoint specific brain areas and mechanisms associated with depression and anxiety
11. Are probiotics a promising treatment strategy for depression?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... ... August 16, 2017 , ... ... through affiliations and de novo development, today announced Cumberland Skin Surgery and ... Skin Surgery and Dermatology, with offices in both Hermitage and Lebanon, Tennessee, provides ...
(Date:8/16/2017)... Kansas City, KS (PRWEB) , ... August 16, ... ... announced the latest beneficiary of their recently launched community enrichment program. Partnering once ... fundraising for the KC Superstar competition to help find the area’s very own ...
(Date:8/16/2017)... ... 16, 2017 , ... Maury Regional Health has announced a large-scale adoption of ... AccuVein devices, Maury Regional Medical Center is making vein visualization part of their standard ... stick and more importantly, helps our staff members locate a vein that will provide ...
(Date:8/16/2017)... ... 16, 2017 , ... The Southeastern Telehealth Resource Center at ... renewing its funding from the Health Resources and Services Administration (HRSA), part of ... fourth time the HRSA administration has renewed its financial support to GPT since ...
(Date:8/16/2017)... ... ... Paul Vitenas, MD, FACS , is honored to announce that he has ... nation’s top physicians, in a variety of specialties. This marks the fourth year in ... coveted ranking. , Castle Connolly is the nation’s trusted provider of information on the ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... HOUSTON , Aug. 15, 2017   Mostyn Law ... in Houston, Texas . The Mostyn Law ... the past 2 years. That is why Mostyn Law ... Texas to show its appreciation. Blood supplies ... to fall 5% short of hospital needs in August. That is ...
(Date:8/15/2017)... Aug. 15, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Michigan residents. Naloxone is ... retail pharmacy, G-3320 Beecher Road. ... Food and Drug Administration, is intended to block or ... breathing, and loss of consciousness. The medication is often ...
(Date:8/15/2017)... , Aug. 15, 2017  Axium Pharmaceuticals Inc., the creator of ... to be in the beginning stages of an IPO. ... epilepsy medications with the average cost of a prescription epilepsy drug being ... AXIUM ... Another staggering figure is the fact that ...
Breaking Medicine Technology: