Navigation Links
JCI online early table of contents: July 18, 2011
Date:7/18/2011

EDITOR'S PICK: IDOLizing low cholesterol

High levels of 'bad' cholesterol (LDL cholesterol) are a risk factor for developing atherosclerotic cardiovascular disease (ASCVD) a disease of the major arterial blood vessels that is one of the major causes of heart attack and stroke. Although the use of statins and the adoption of lifestyle changes to reduce LDL cholesterol levels have decreased the incidence of and mortality from ASCVD, many individuals fail to reach target levels of LDL cholesterol. Researchers are therefore seeking new targets for LDL cholesterollowering therapeutics. Human genetic and mechanistic studies by a team of researchers, led by Pivi Pajukanta, at the David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, has now identified the protein MYLIP (also known as IDOL) as a potential new target in this context.

TITLE: The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans

AUTHOR CONTACT:
Pivi Pajukanta
David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Phone: 310.267.2011; Fax: 310.794.5446; E-mail: ppajukanta@mednet.ucla.edu.

View this article at: http://www.jci.org/articles/view/45504?key=d5edfd2925fed609d5f4

ONCOLOGY: Platinum-based drugs: double trouble for tumors

One of the reasons that tumors are able to grow rapidly is that they actively prevent immune cells from generating effective antitumor immune responses. Researchers are developing approaches to combat the mechanisms used by tumors to inhibit immune responses, but such approaches don't kill tumor cells directly. A team of researchers, led by Jolanda de Vries and Joost Lesterhuis, at Radboud University Nijmegen Medical Centre, Netherlands, has ide
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5 6 7

Related medicine news :

1. TheReliefPlace.com Launches Online Store “The Relief Shop” - What Does this Medical Supply Store Carry and How Can They Help You?
2. Web Content Management Enables Government Transparency, Participation, and Collaboration Online
3. DavisPTnetwork Partners with the New York Physical Therapy Association to Provide Online Continuing Education
4. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
5. Pharmahelper Pleased To Recognize Online Pharmacy Practice Standards Announced By Google Adwords
6. Online Dating Reinvents Itself with the Recent Roll-Out of Teacherhookup.com, a Free Website that Focuses on a Person's Career in Education!
7. EdenHome.com Adds Aventura Organic Clothes to Site and Announces Largest Online Selection of Stylish Organic Clothes for Men, Women and Children
8. Fire Protection Online Resolves Safety Concerns with CO2 Fire Extinguishers
9. JCI online early table of contents: Feb. 15, 2010
10. Fitness Trend Towards Online Personal Training Gets Real-World Weight Loss Results on FitOrbit.com
11. New Online Store Makes Buying Cosmetics a Healthy Choice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2013)... Keith Chertok now provides gum disease patients with a new ... chance of a healthier smile. Laser gum surgery ... removes diseased gum tissue in patients, but it also stimulates ... implants. , LANAP uses a laser to successfully treat ... the healthy tissue as well as encourage new bone growth. ...
(Date:5/19/2013)... Nevada (PRWEB) May 19, 2013 Vegas ... , is proud to announce the launch it's all ... at the MGM Grand on 5/19/2013. Consumers traveling to ... new special pricing available on VegasHotelEscapes.com's website. Travelers will ... they beat any competitors price. , Vegas Hotel Escapes ...
(Date:5/19/2013)... Agora Health Limited developed by Rachael Linkie ... how to increase memory power naturally and effectively. ... helps people re-new their entire health from the inside out. ... by a fatigued mind. In addition, the program helps people ... lifetime. The author claimed that this program can help people ...
(Date:5/19/2013)... Passages Malibu, the leading non-12 step, holistic, and ... the launch of a “Sobriety, Health, and Wellness” survey ... “We are always looking for new ways to engage ... regarding sobriety, what’s working for people, and what isn’t,” ... Passages Addiction Treatment Centers located in Malibu and ...
(Date:5/19/2013)... Argentina: Yoga classes ( clases de Yoga ) will ... Sivananda Yoga Vedanta Center. The center is located ... are 90 minutes and are offered all week long. ... environment, allowing visitors to enjoy the benefits of Yoga, ... , The Yoga classes follow the following principles: , ...
Breaking Medicine News(10 mins):Health News:Berkeley, CA Periodontist, Dr. Keith Chertok Now Treats Gum Disease Patients With Laser Gum Surgery Prior to Placing Dental Implants 2Health News:How To Increase Memory Power | How “Agora Health Limited” Helps People Improve Their Memory Naturally And Effectively – Health Review 2Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 2Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 3Health News:Clases de Yoga in Buenos Aires, Argentina (Yoga Classes) Now Offered by Sivananda Yoga Vedanta Center 2
... UTRECHT, The Netherlands, November 2 InteRNA Technologies,B.V. ... entered into a,research agreement to develop microRNA (miRNA)-based ... Under the research collaboration with Associate Professor William ... unique,lentiviral-based miRNA overexpression library will be applied in,multi-parametric, ...
... ... cigarette cartridge, may prevent pneumonia, influenza, and other respiratory diseases. These findings are based ... of Chicago,s Billings Hospital in 1942 on inhalation of vaporized propylene glycol in laboratory ... (PRWEB) ...
... Driving Prevention Week(R) to Prevent Fall-Asleep Crashes With Tips and Countermeasures ... as a major contributor to vehicle crashes. The National Sleep Foundation,s ... as many as 1.9 million drivers have had a car crash ... Even more surprising, 54% of drivers (105 million) have driven while ...
... 5, 2009, at 8:30 a.m. Eastern/2:30 p.m. Central European/5:30 a.m. ... CTIC) management team will host a conference call to discuss ... Conference Call Numbers, Thursday, November ... a.m. Pacific Time, 1-877-941-6010 (US Participants), ...
... England, Nov. 1 THURSDAY saw over 100 people, ... Celebrity MasterChef winner Liz McClarnon and model Charlotte Mears, ... cosmetic surgery clinic from Transform. The new state of ... now the 22nd cosmetic surgery clinic by Transform - ...
... , SUNDAY, Nov. 1 (HealthDay News) -- Dialysis patients with very ... people on dialysis, even those with the highest levels of body ... percentage in 671 dialysis patients in California. In the next five ... body fat was 2½ to three times higher than it was ...
Cached Medicine News:Health News:InteRNA Technologies and Dana-Farber Cancer Institute to Collaborate on the Role of microRNAs in Cancer Pathways 2Health News:Vaporized Propylene Glycol, a Key Ingredient in Electronic Cigarettes, May Prevent Pneumonia, Influenza, and Other Respiratory Diseases 2Health News:1.9 Million Drivers Have Fatigue-Related Car Crashes or Near Misses Each Year 2Health News:1.9 Million Drivers Have Fatigue-Related Car Crashes or Near Misses Each Year 3Health News:1.9 Million Drivers Have Fatigue-Related Car Crashes or Near Misses Each Year 4Health News:Nicky Hambleton-Jones Supports Launch of State-of-the-Art London Cosmetic Surgery Clinic 2
(Date:5/17/2013)... , May 17, 2013  Sony Biotechnology Inc. ... SP6800 Spectral Analyzer (SP6800).  Sony will be exhibiting and ... will be held at the San Diego ... California , from May 20 - 22.  ... analytical system, incorporating commercial audio-visual technologies into new and ...
(Date:5/17/2013)... announced that it will report its 2013 first quarter earnings on Wednesday, ... Ed Borkowski , CFO, will host an analyst and investor ... participate in the conference call within the U.S. and Canada ... call outside the U.S. and Canada , dial (760) ... should dial in 10 minutes prior to the start of the call. ...
(Date:5/17/2013)... , May 17, 2013  Boehringer Ingelheim will ... disease at the American Thoracic Society International Conference ... , May 17 – 22. Data ... for the treatment of chronic obstructive pulmonary disease ... well as investigational compounds for asthma, idiopathic pulmonary ...
Breaking Medicine Technology:Sony Biotechnology Inc.'s New Technology for Science Provides Researchers Results in Color 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 3Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 4Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 5Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 6Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 7Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 8
... Influenza Conference, HIGH WYCOMBE, England, June 18, 2007 ... new flu vaccine has the,potential to protect against ... presented today by PepTcell, at the 2007,Options for ... Canada. , The pre-clinical results, which will be ...
... 18, 2007-Active Biotech (OMX Nordic: ACTI),has presented ... the 8th,World Congress on Inflammation (<a target="_blank" ... "The results strengthen the further clinical development ... show the possibility to reduce,the use of ...
Cached Medicine Technology:New Flu Vaccine From PepTcell Could Provide Immunity Against All,Strains of Influenza Virus 2New Flu Vaccine From PepTcell Could Provide Immunity Against All,Strains of Influenza Virus 3New Flu Vaccine From PepTcell Could Provide Immunity Against All,Strains of Influenza Virus 4Active Biotech presents new pre-clinical data for the 57-57 project,at the 8th World Congress on Inflammation 2
The Antibacterial Personal Catheter® features a unique silicone composition that provides an antibacterial coated soft outer layer of silicone combined with a firm inner layer....
... on delicate urethral tissues. The ... coating provide nearly friction-free movement, ... easy to maintain sterility. You ... its own sterile water, avoiding ...
The Gizmo male external catheter is a latex catheter that uses a single-sided adhesive strip....
... Pak Seven Starter Kit: a ... of Freedom Clear catheters and ... 100% latex-free along with ... convenience and comfort. Plus each ...
Medicine Products: