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Infection linked to dangerous blood clots in veins and lungs, U-M study shows
Date:4/3/2012

Research shows iOlder adults who get infections of any kind such as urinary, skin, or respiratory tract infections are nearly three times more likely to be hospitalized for a dangerous blood clot in their deep veins or lungs, University of Michigan Health System research shows.

The most common predictor of hospitalization for venous thromboembolism a potentially life-threatening condition that includes both deep-vein and lung blood clots was recent exposure to an infection, according to the study released April 3 ahead of print in Circulation.

"Over half of older Americans who were hospitalized for such blood clots had an infection in the 90 days prior to the hospitalization," says lead author Mary Rogers, Ph.D., M.S., research assistant professor in Internal Medicine at the University of Michigan Medical School and research director of the Patient Safety Enhancement Program at the U-M Health System and the VA Ann Arbor Healthcare System.

"This is important because infections are common and many people do not link infections with developing blood clots. In fact, many educational websites do not list infections as a risk factor for blood clots but they are."

The study comes as the rate of hospitalization for venous thromboembolism steadily increases in the United States, with more than 330,000 hospital admissions for this condition a year.

"We would like to decrease the number of preventable hospitalizations, both for the benefit of the patient and to help bring down the cost of medicine," says Rogers, pictured left. "We wanted to study the triggers of hospitalization to help us understand what is driving such admissions and to think about actions we can take in order to prevent these hospitalizations."

If the infection occurred during a previous hospital or nursing home stay, patients were nearly seven times more likely to be admitted for a blood clot. Those who got the infection at home were nea
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Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

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