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IBD, LCPD health research in 'Westie' dogs may hold answers to similar human diseases
Date:7/18/2011

rly 127,000 points in the dog genome. The goal of this project is to identify genes that contribute to the development of LCPD.

Preliminary study findings show LCPD may be inherited in much the opposite way previous studies have shown. Eariler studies suggested LCPD is transmitted in an autosomal recessive pattern. "Our current data suggest the LCPD is inherited in either a dominant or complex fashion," said Keith E. Murphy, PhD of Clemson University. "Only with more samples will we begin to understand the genetics controlling LCPD." The investigators currently have samples from 58 Westies, 23 of which have LCPD. One candidate gene identified in humans was investigated in canine LCPD, but was not associated with LCPD in Westies. The results of the candidate gene analysis will be published later this year.

"We are pleased to see such progress in the study of Westies and are even more excited that our work may contribute to human disease research, as well," said Bebe Pinter, president of WFA. "We anxiously await final results in these studies and in other studies currently being funded by WFA and CHA and look forward to continuing our commitment to research and funding for Westie health."


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Contact: Teresa Barnes
TeresaRBarnes@gmail.com
303-521-4080
Westie Foundation of America
Source:Eurekalert

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