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HIV rate in SF could be cut sharply with expanded treatment, study predicts
Date:4/13/2011

idual, HIV treatment can reduce the likelihood of HIV transmission to other persons. We found that, just by changing the strategy of when to start treatment in individuals already in care, our model predicts significant reductions in new HIV infections among men who have sex with men in San Francisco."

In addition, the study found that adding annual HIV testing for men who have sex with men in the city to universal treatment could bring the reduction in new infections down by 75 percent, the researchers report in their paper. "Our findings show that we can obtain even greater reductions in new HIV infections if we do a better job of encouraging people to get tested, continue to improve our linkages to care and offer treatment to all HIV patients," said study co-author, Diane V. Havlir, MD, chief of the UCSF Division of HIV/AIDS at San Francisco General Hospital.

Researchers modeled three expanded antiretroviral treatment scenarios in San Francisco: one being the current standard of care where treatment is offered to HIV-infected patients with CD4 cell counts below 500, the second offering treatment to all HIV patients receiving care and the third strategy combining intensified annual HIV testing for men who have sex with men with treatment for all HIV-infected patients.

The model predicts that the implementation of the third strategya full "test and treat" approachin San Francisco would cut in half the percentage of men who have sex with men living with HIV in the city from its current level of about one in four to one in eight in twenty years.

"Our clinicians recommended initiating antiretroviral therapy to all of our HIV positive patients based on our assessment that delaying treatment allows the virus to do damage to major organs systems and would lead to poorer outcomes for patients. It is too early to tell if this shift in treatment strategy last year by our clinic and the Department of Public Health has had any impact in
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Contact: Jeff Sheehy
jsheehy@ari.ucsf.edu
415-597-8165
University of California - San Francisco
Source:Eurekalert

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