Navigation Links
Genetic variant and autoantibodies linked to having a child with autism
Date:10/19/2011

A study by researchers at UC Davis has found that pregnant women with a particular gene variation are more likely to produce autoantibodies to the brains of their developing fetuses and that the children of these mothers are at greater risk of later being diagnosed with autism.

The finding is the first to demonstrate a genetic mechanism at play in the development of the neurodevelopmental disorder among some children -- offering the possibility of a genetic test for some women at risk for having a child with autism, said Judy Van de Water, an immunologist and the study's co-principal investigator.

"Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression," is published online today in the journal Translational Psychiatry, a Nature publication.

"Our study gives strong support for the idea that, in at least some cases, autism results from maternal immunity gone overboard," said Judy Van de Water, a professor of internal medicine and a researcher affiliated with the UC Davis MIND Institute. "This is the first time that a genetic factor known to be important in autism and its effects have been demonstrated."

Autism is a neurodevelopmental disorder that affects a child's ability to learn and communicate socially. It affects an estimated 1 in 110 children in the United States, according to the U.S. Centers for Disease Control and Prevention.

For the study, Van de Water and her colleagues examined the action of the MET gene, which has a known association with autism, among 200 mothers of children with autism and 150 mothers of typically developing children enrolled in the Northern California-based Childhood Autism Risks from Genetics and the Environment (CHARGE) Study. All of the study participants were between 24 and 60 months of age at the time of study enrollment, lived with one biological parent, and spoke either English or Spanish
'/>"/>

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. Obstructive Sleep Apnea in Kids May Have Genetic Cause
3. Epigenetic signals differ across alleles
4. Study reveals genetic link between mammographic density and breast cancer
5. Genetic Risk Score Doesnt Spot Heart Trouble in Women
6. Penn researchers find genetic link to leukemias with an unknown origin
7. Scientists Spot Genetic Fingerprints of Individual Cancers
8. Genetic health risks in children of assisted reproductive technology
9. Genetic Mutation Linked to Prostate Cancer in Blacks
10. Protecting the brain from of a deadly genetic disease
11. Protecting the brain from a deadly genetic disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... it when a woman harried by hot flashes says ... study published online in Menopause , the journal ... with objective tests that what these women say about ... studies showed that hot flashes were related to memory ... though there was a relationship between hot flashes and ...
(Date:5/23/2013)... Susquehanna Health is now a ... training course for adolescents age 11 and up. ... Dr. Patricia Keener after a colleague’s toddler choked to ... who didn’t know how to provide first aid. Safe ... medical basis that aims to reduce the number of ...
(Date:5/23/2013)... An anti-cancer drug about to be tested in a ... a possible treatment for Alzheimer,s disease has failed to ... plague Alzheimer,s patients, according to results of a study ... a professor of neuroscience affiliated with the Evelyn F. ... of Florida, emphasized the importance of verifying promising research ...
(Date:5/23/2013)... The Rottenstein Law Group LLP, a New ... Tylenol Lawsuit Information Center at http://www.rotlaw.com/tylenol , dedicated ... who are considering filing lawsuits. , The painkiller ... liver damage, according to a 2009 report from the ... communication,” the FDA warned consumers against using more than ...
(Date:5/23/2013)... Former United States Vice President Dick Cheney served as ... Luncheon. , In front of 1,500 guests yesterday ... saying, "I am delighted to be here to have ... the Year Award. I think it's a tremendous recognition; ... a company like this because there are obviously a ...
Breaking Medicine News(10 mins):Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 3Health News:Anti-cancer drug viewed as possible Alzheimer's treatment doesn't work in UF study 2Health News:Anti-cancer drug viewed as possible Alzheimer's treatment doesn't work in UF study 3Health News:Rottenstein Law Group LLP Now Accepting Tylenol Cases, Announces New Tylenol Lawsuit Information Center 2Health News:Acadian Ambulance Honors Paramedic of the Year at Annual Luncheon 2
... this summer and a friend dares you to eat a raw ... hospital with a severe parasitic infection. Physicians at Washington University ... infection in six people who had consumed raw crayfish from streams ... years, but three have been diagnosed since last September; the latest ...
... ... statistics on the top-performing companies for the past six months, Jusuru International is the fastest ... ... has just released its statistics on the top-performing companies for the past six months, Jusuru ...
... Massachusetts Medical School report in the journal Nature Medicine ... malignant glioma, a pathway essential to the cancer,s ability ... that would stop the cancer,s ability to thrive. ... RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway ...
... infection improves patient outcomes, researchers say , TUESDAY, May ... ailment chronic obstructive pulmonary disease (COPD) do better when ... , COPD patients who were given antibiotics early in ... ventilation and less likely to have to be readmitted ...
... ... Version of Pearson Author Elana Zucker’s Best-selling Textbook, Being a Home Health Aide , ... Indianapolis, IN (PRWEB) May 25, 2010 ... decade, the Indiana Home and Hospice Care (IHHC) Foundation needed to quickly overhaul its outdated ...
... suggest that bacteria residing in the the human intestinal ... developing colon cancer. Scientists from the University of Florida ... of the American Society for Microbiology in San Diego, ... are more frequently detected in subjects with polyps, early ...
Cached Medicine News:Health News:Dangerous lung worms found in people who eat raw crayfish 2Health News:Dangerous lung worms found in people who eat raw crayfish 3Health News:Dangerous lung worms found in people who eat raw crayfish 4Health News:,Jusuru Tops New Company Launch Rankings, 2Health News:Novel RNA interference screening technique identifies possible path for malignant glioma treatment 2Health News:Quick Use of Antibiotics Best for COPD Flare-Ups 2Health News:Quick Use of Antibiotics Best for COPD Flare-Ups 3Health News:Indiana Home and Hospice Care Foundation Selects Pearson to Bolster Workforce Training Initiatives 2Health News:Indiana Home and Hospice Care Foundation Selects Pearson to Bolster Workforce Training Initiatives 3
(Date:5/23/2013)... May 23, 2013  BioElectronics Corporation (OTC Pink: BIEL), ... comments on the FDA panel meeting for non-thermal shortwave ... – Pulsed Shortwave Therapy Meeting was held on May ... USA.  The focus of the meeting was very narrow, ... focus solely on the application of non-thermal shortwave diathermy ...
(Date:5/23/2013)... May 23, 2013 Halozyme Therapeutics, Inc. ... appointment of David A. Ramsay ... most recently Vice President, Corporate Development at Halozyme. ... "With his established financial management experience and ... working in our commercial group for the last ...
(Date:5/23/2013)... , May 23, 2013 Isis Pharmaceuticals, Inc. ... today announced that management will present a company overview at ... Conference on Thursday, May 30, 2013 at 8:40 a.m. ET ... live audio webcast of the presentation will be available on ... www.isispharm.com .  A replay will be available on the ...
Breaking Medicine Technology:BioElectronics and Pulsed Shortwave Therapy Make Progress 2Halozyme Therapeutics Names David A. Ramsay Chief Financial Officer 2Isis Pharmaceuticals to Present at the Deutsche Bank 38th Annual dbAccess Health Care Conference 2
... Pfizer Inc. (NYSE: PFE ) today announced, at the ... the chronic low back pain and painful diabetic peripheral neuropathy studies in ... continues in some areas of high unmet medical need, including cancer pain. ... (Logo:   http://photos.prnewswire.com/prnh/20100416/PFIZERLOGO ...
... Heslin , MD of Bridge Street Medical Group will discuss use of health IT ... 20 , , , ... July 19 If a small general medical practice in ... health care for its patients, so can practices across the nation. That is the ...
Cached Medicine Technology:Pfizer Suspends Chronic Pain Studies in Tanezumab Clinical Trial Program; Some Studies Continue in Areas of Unmet Medical Need 2Hudson Valley Physician Testifies Before House Health Subcommittee Tuesday About Incentives for Adoption of Health Information Technology 2Hudson Valley Physician Testifies Before House Health Subcommittee Tuesday About Incentives for Adoption of Health Information Technology 3
... The FLU OIA test is a ... diagnosis of Influenza A and B with ... answer in just over 15 minutes. Assay ... specimen flexibility, and performance equivalent to 14-day ...
The CdTOX A OIA gets the results you need without specimen extraction or instrumentation. Results are available in minutes vs hours or days for EIA or other methods. The combination of performance, ...
... provides superior performance for the diagnosis ... that provides an answer in 6 ... will convince you of this tests ... deliver improved patient care with a ...
... for Botox therapy and nerve block ... injectable needle has a precisely machined ... with an attached 61-cm (24-in) lead ... insertion. Single patient use only. A ...
Medicine Products: