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Genes, environment, or chance?
Date:2/18/2010

gh of the protein to activate the final gene. Others made too few transcripts and the final gene stayed off.

DNA winds tightly around proteins, like thread around a spool, and must uncoil for the transcriptional machinery to access a gene.

Some proteins unwind the DNA; others wind it up again. In the mutant worms, the balance shifted to favor the proteins that keep DNA wound. But in some of the worms, the DNA stayed uncoiled long enough to generate sufficient numbers of transcripts to activate the final gene. And so, by chance, those worms developed a gut.


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Contact: Scott Rifkin
scinews@ucsd.edu
University of California - San Diego
Source:Eurekalert  

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