Navigation Links
deCODE discovers genetic markers that improve the power of PSA testing for detecting prostate cancer
Date:12/15/2010

ting portfolio," said Kari Stefansson, CEO of deCODE and senior author on the study.

The paper, entitled "Genetic correction of PSA values using sequence variants associated with PSA levels," is published today online in Science Translational Medicine at www.ScienceTranslationalMedicine.org and will appear in an upcoming print edition of the journal. The study was conducted in several stages and involved tens of thousands of men with and without prostate cancer. First, more than 300,000 SNPs were analyzed in 16,000 Icelandic men with PSA measurements but who had never been diagnosed with prostate cancer. SNPs that correlated with PSA levels were identified and then validated in a cohort from the UK. These SNPs were then studied in large case-control cohorts from Iceland, the Netherlands, Spain, Romania and the US to establish the association with PSA levels independent of risk of prostate cancer itself. The authors then demonstrated how measuring four SNPs correlated with PSA levels can be used to obtain a personalized threshold for when to biopsy, and that using such thresholds improves the ratio of positive to negative biopsies. The greatest improvement in prediction accuracy was seen when men are tested both for the PSA correction SNPs as well as a panel of prostate cancer risk SNPs detected by the deCODE ProstateCancer test.


'/>"/>

Contact: Edward Farmer
edward.farmer@decode.is
354-863-1923
deCODE genetics
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientists decode secrets of a very common virus that can cause cancer
2. Physicists use graphene to decode DNA
3. The language of RNA decoded: Study reveals new function for pseudogenes and noncoding RNAs
4. UT professor defines play, discovers even turtles need recess
5. Research discovers how the deaf have super vision
6. Colorado researcher discovers mechanism for changing adult cells into stem-like cells
7. Researcher at Childrens Hospital LA discovers way to overcome radiation resistance in leukemia
8. TGen-Mayo Clinic study discovers role of DNA methylation in multiple myeloma blood cancer
9. Virginia Tech professor discovers new TB pathogen
10. UCSF-led team discovers familial link in rare childhood leukemia
11. UR discovers new way to boost vaccines, seeks patent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... Medicine scientists could lead to potential new treatments for ... scleroderma. , Fibrosis, or scarring, is a hallmark ... and lungs can lead to serious organ damage and, ... therapeutic options centers on findings made by Swati Bhattacharyya, ... role that a specific protein plays in promoting fibrosis. ...
(Date:4/17/2014)... identified new pain relief targets that could be ... researchers at King,s College London made the discovery ... the periphery of the body. , Dr Marzia ... mechanisms underlying pain generation and our findings could ... effects." , One potential side effect of some ...
(Date:4/17/2014)... at the University of California, San Diego School of ... who have suffered a recent major loss are more ... adults. , The study is published in this month,s ... . , Because compassionate behaviors are associated with better ... offer insights into ways to improve the outcomes of ...
(Date:4/17/2014)... synthetic biology team has created a new technology ... that could travel the body and selectively target ... cell-based, biological devices that monitor and modify human ... biology. However, no existing technology enabled bioengineers to ... state and respond in a customized fashion. , ...
(Date:4/17/2014)... NY (April 16, 2014) The cause of neuronal ... new study proposes that neurons may be mistaken for ... system, similar to the way autoimmune diseases like type ... body,s cells. The study was published April 16, 2014, ... new, and likely controversial, idea in Parkinson,s disease; but ...
Breaking Medicine News(10 mins):Health News:New clues on tissue scarring in scleroderma 2Health News:New pain relief targets discovered 2Health News:The ilk of human kindness 2Health News:Building 'smart' cell-based therapies 2Health News:Is Parkinson's an autoimmune disease? 2
... ... relax patients, treat TMJ disorders and improve dental procedures. , ... Miami, FLA. (PRWEB) -- In addition to cosmetic dentistry services, ... at Miami Beach Dental Institute now offer dental massage to patients. Dr. Nassery teams up ...
... who have been treated for breast cancer can choose to ... put them at higher risk of dying from their cancer, ... of 14 trials, presented today (Friday) at the seventh European ... that, not only was pregnancy safe for breast cancer survivors, ...
... of prescription drugs skyrocketing in the United States, the ... for Social Policy and Management at Brandeis University to ... of these drugs: the PMP Center of Excellence. ... from DOJ,s Bureau of Justice Assistance (BJA), the Center ...
... more women are delaying motherhood, researchers say , THURSDAY, March ... become pregnant after having had breast cancer may actually improve ... experts had thought. , The finding is significant, given ... decline and more women are delaying pregnancy until later in ...
... SoCal Cleanse, a company focused ... Best of Show Award from VegNews at the 2010 Natural Products Expo West show. SoCal ... cleansing line. , ... -- SoCal Cleanse was tapped as winner of the VegNews Best of Show Award ...
... of children and up to 70 percent of adults in ... In recent years, doctors have come to believe that this ... that generate the immature blood cells characteristic of leukemia and ... Hospital Boston have found a possible way to kill off ...
Cached Medicine News:Health News:Top Miami Dentist, Dr. Hamid Nassery, Offers Dental Massage Services For Patients 2Health News:Pregnancy for breast cancer survivors: Meta-analysis reveals it is safe and could improve survival 2Health News:Pregnancy for breast cancer survivors: Meta-analysis reveals it is safe and could improve survival 3Health News:A prescription for excellence 2Health News:Pregnancy May Protect Breast Cancer Survivors 2Health News:Pregnancy May Protect Breast Cancer Survivors 3Health News:SoCal Cleanse Wins 2010 VegNews Best of Show Award 2Health News:Targeting cell pathway may prevent relapse of leukemia 2Health News:Targeting cell pathway may prevent relapse of leukemia 3
(Date:1/15/2014)... PALM BEACH GARDENS, Fla. , Jan. 15, 2014  In an ... C. difficile and TB in ambulances and other transport vehicles, an ... being used by rescue personnel for the first time. ... coming in contact with these deadly pathogens, West Palm ...
(Date:1/15/2014)... 2014 The Cadence Fitness & Health Center has ... Medical Fitness Association, a non-profit organization assisting medically integrated ... The Cadence Fitness & Health Center is the only ... in the Chicagoland area. "The certification means ...
(Date:1/15/2014)... 2014  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 ... by its indirect wholly-owned subsidiary, Sapphire Subsidiary Corp. ("Purchaser"), ... of Solta Medical, Inc. (NASDAQ: SLTM ) ...
Breaking Medicine Technology:Superbugs No Longer Ride In Rescue Vehicles 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... , HOPKINTON, Mass., Nov. 2 Caliper Life Sciences, Inc. ... tools, presented at a training session for reviewers from the ... of the LabChip GX platform for high throughput screening and ... accept the FDA,s invitation to present our LabChip platform to ...
... This week begins American Diabetes Month® - a ... the launch of a new campaign by the American Diabetes ... and one of its National Strategic Partners, Liberty Medical Supply, ... give diabetes patients practical tips and advice for living with ...
Cached Medicine Technology:Caliper Life Sciences Presents LabChip(R) Platform to the U.S. Food and Drug Administration 2Educational Video Series Released for American Diabetes Month 2Educational Video Series Released for American Diabetes Month 3Educational Video Series Released for American Diabetes Month 4
... In the way it implements the ... 510 Meta system is unmatched. It allows ... compromising resolution and efficiency. Unprecedented flexibility for ... functions that guarantee fast and efficient structural ...
... first inverted microscope to take full advantage ... design enables optical input/output of light and ... and detector equipment. Extendable "Stratum Structure" configuration ... source and other attachments within the infinity ...
... with direct digital output. Three-chip color camera ... wide array of high-quality color video cameras ... flexibility you need for an efficient viewing ... real-time image of your specimen that can ...
... The PM30 is a premium photomicrography ... quality photomicrographs of even the most difficult ... the new PM30 system provide solution to ... addition to their automatic exposure control, the ...
Medicine Products: