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d’Oliveira & Associates Seeks Clients That Have Been Affected by the Prescription Drug Topamax
Date:3/23/2013

(PRWEB) March 23, 2013

Topamax is a popular anticonvulsant prescription drug manufactured by the Johnson & Johnson subsidiary Ortho-McNeil Pharmaceutical. Originally approved by The U.S. Food and Drug Administration (FDA) in 1996 to treat persons experiencing epileptic seizures, the drug has since been approved as an anti-migraine drug and has thus become a popular drug for both combating epileptic seizures and migraines*. In just 2007 to 2010 alone, nearly 4.3 million patients filled prescriptions to Topamax*. However, in March 2011, the FDA warned that pregnant users of Topamax are at an increased risk that their children will develop birth defects as a result of the drug use*.

Specifically, the FDA's recent study into Topamax revealed that pregnant woman using the migraine and seizure drug exposed their children to an increased risk of developing cleft lip and cleft palate*. Cleft lip is a birth defect where the infant lacks the tissue needed to correctly form the upper lip during pregnancy and results in vertical gaps remaining in the child's lip. Similarly, cleft palate is a birth defect where the child is left with gaps in the back portions and sides of the mouth due to a lack of tissue required for formation during the pregnancy. Both conditions put the child at risk for chronic hearing loss, eating and drinking problems, speech development problems, and even poor overall growth.

In its warning, the FDA has cited a recent study by The Northern American Antiepileptic Drug Pregnancy Registry, which concluded that infants exposed to Topamax (topiramate) during pregnancy are three times more at risk of developing these defects than infants exposed to competing seizure and migraine drugs. According to the study, only 0.38% of infants exposed to other various
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