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A less painful colonoscopy
Date:4/27/2011

n the journal Optical Engineering.

Using a prototype, the Tufts engineers embedded quantum dots -- nano-sized crystals of semiconductor material -- circumferentially at intervals along the length of an optical fiber. The researchers stretched the fiber around a metal cylinder to create a bending effect. They then injected a laser light beam into the fiber's inner core from one end.

The fiber's core released light as it is bent. This activated the quantum dots. Instantly, the dots reemitted light signals of varying intensity to a spectrometer. With this data, the researchers were able to measure the degree of curvature in the fiber. From the position of the activated dots, the researchers were also able to calculate the direction of the bend. "The greater the bend, the more intense the light emissions," says Cao.

In a separate experiment, the team used an inanimate model colon made of polyurethane foam.. They inserted the modified fiber inside an endoscope and then threaded the device into the model. The researchers were able to produce a video image by sending the data through a digital processor which created a real-time image of the scope in the model colon.

Cao notes, "Physicians can use the image on the monitor to guide them. They'll know exactly where the end of the point is, as well as the shape of the scope inside the colon."

Colorectal cancer is the third leading cause of cancer-related deaths in the United States, with 102,900 new cases diagnosed in 2010, according to most recent estimates from the American Cancer Society.

Colon cancer has a high cure rate provided it is detected early. Most men and women are advised to undergo periodic colonoscopies beginning at age 50.

The commercialization of EFOST is being managed by Tufts University's Office for Technology Licensing and Industrial Collaboration. There are currently patents s pending in the USA, Canada, Europe, Japan and Austr
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Contact: Alex Reid
alexander.reid@tufts.edu
617-627-4173
Tufts University
Source:Eurekalert

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